Showing entry for Anacardic Acid


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0024070
Compound NameAnacardic Acid
Structure
FormulaC22H30O3
InchiKeyQUVGEKPNSCFQIR-UTOQUPLUSA-N
SMILESC=CC/C=C\C/C=C\CCCCCCCc1cccc(c1C(=O)O)O
InchiInChI=1S/C22H30O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-17-15-18-20(23)21(19)22(24)25/h2,4-5,7-8,15,17-18,23H,1,3,6,9-14,16H2,(H,24,25)/b5-4-,8-7-
IUPAC2-hydroxy-6-[(8Z,11Z)-pentadeca-8,11,14-trienyl]benzoic acid
Molecular Weight342.22
Pubchem Id9875131
Chembl IdCHEMBL455368
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50292429
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT012241 Decaprenyl diphosphate synthase reviewed uppS - 280000 - -
reviewed BXGT019380 Histone acetyltransferase KAT2B reviewed KAT2B - 33900 - -
reviewed BXGT006736 Seed linoleate 13S-lipoxygenase-1 reviewed LOX1.1 - >250000 - -
reviewed BXGT019380 Histone acetyltransferase KAT2B reviewed KAT2B - 1000000 - -
reviewed BXGT008777 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal reviewed - - 28000 - -
reviewed BXGT008777 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal reviewed - 4000 - - -
reviewed BXGT008777 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal reviewed - 6000 - - -
reviewed BXGT008777 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal reviewed - 2000 - - -
reviewed BXGT019403 Histone acetyltransferase KAT5 reviewed KAT5 - 64000 - -
reviewed BXGT019380 Histone acetyltransferase KAT2B reviewed KAT2B - 8500 - -
reviewed BXGT013038 Histone acetyltransferase p300 reviewed EP300 - 5000 - -
reviewed BXGT020493 Histone acetyltransferase KAT8 reviewed KAT8 - 43000 - -
reviewed BXGT019403 Histone acetyltransferase KAT5 reviewed KAT5 - 9000 - -
reviewed BXGT019403 Histone acetyltransferase KAT5 reviewed KAT5 - 374590 - -
reviewed BXGT013038 Histone acetyltransferase p300 reviewed EP300 - >1000000 - -
reviewed BXGT019380 Histone acetyltransferase KAT2B reviewed KAT2B - 667050 - -
CHEMBL CHEMBL455368
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q92993 BXGT019403 Histone acetyltransferase KAT5 reviewed - KAT5 Inhibition - - -
P22513 BXGT008777 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal reviewed - Ki '=' 2000 nM
P22513 BXGT008777 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal reviewed - Ki '=' 4000 nM
Q09472 BXGT013038 Histone acetyltransferase p300 reviewed - EP300 IC50 '>' 1000000 nM
Q09472 BXGT013038 Histone acetyltransferase p300 reviewed - EP300 Activity '=' 53 %
Q92830 BXGT019379 Histone acetyltransferase KAT2A reviewed - KAT2A Activity '=' 112 %
Q92831 BXGT019380 Histone acetyltransferase KAT2B reviewed - KAT2B Activity '=' 52 %
Q09472 BXGT013038 Histone acetyltransferase p300 reviewed - EP300 IC50 '=' 5000 nM
Q99MK2 BXGT019992 Histone acetyltransferase KAT5 reviewed - Kat5 Inhibition - - -
Q9H7Z6 BXGT020493 Histone acetyltransferase KAT8 reviewed - KAT8 IC50 '=' 43000 nM
Q92793 BXGT019374 CREB-binding protein reviewed - CREBBP Activity '=' 44 %
Q2V0Y6 BXGT014239 Beta-lactamase unreviewed - pse-1 IC50 '=' 1100 ug.mL-1
P62593 BXGT011438 Beta-lactamase TEM reviewed - bla; IC50 '=' 800 ug.mL-1
P24735 BXGT008991 Beta-lactamase reviewed - ampC IC50 '=' 7200 ug.mL-1
Q92793 BXGT019374 CREB-binding protein reviewed - CREBBP Inhibition '=' 62 %
Q92831 BXGT019380 Histone acetyltransferase KAT2B reviewed - KAT2B Inhibition - - -
P05364 BXGT006351 Beta-lactamase reviewed - ampC IC50 '=' 1400 ug.mL-1
P22513 BXGT008777 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal reviewed - Inhibition - - -
Q03330 BXGT012707 Histone acetyltransferase GCN5 reviewed - GCN5 Activity - - -
Q92993 BXGT019403 Histone acetyltransferase KAT5 reviewed - KAT5 IC50 '=' 64000 nM
Q09472 BXGT013038 Histone acetyltransferase p300 reviewed - EP300 Inhibition '=' 40 %
Q92830 BXGT019379 Histone acetyltransferase KAT2A reviewed - KAT2A Activity - - -
Q96GD4 BXGT019667 Aurora kinase B reviewed Kinase AURKB Activity - - -
O14965 BXGT004117 Aurora kinase A reviewed Kinase AURKA Kcat '=' 281 /s
P22513 BXGT008777 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal reviewed - IC50 '=' 28000 nM
Q92793 BXGT019374 CREB-binding protein reviewed - CREBBP Inhibition - - -
Q09472 BXGT013038 Histone acetyltransferase p300 reviewed - EP300 Inhibition - - -
O14965 BXGT004117 Aurora kinase A reviewed Kinase AURKA Activity - - -
P00807 BXGT005664 Beta-lactamase reviewed - blaZ IC50 - - -
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Inhibition '=' 15 %
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Inhibition '=' 45 %
O14965 BXGT004117 Aurora kinase A reviewed Kinase AURKA Km '=' 40250000 nM
Q92831 BXGT019380 Histone acetyltransferase KAT2B reviewed - KAT2B Inhibition '=' 40 %
Q92831 BXGT019380 Histone acetyltransferase KAT2B reviewed - KAT2B IC50 '=' 1000000 nM
O14965 BXGT004117 Aurora kinase A reviewed Kinase AURKA Ka '=' 10 /uM
O14965 BXGT004117 Aurora kinase A reviewed Kinase AURKA Vmax '=' 62 mmol/min/mg
Q09472 BXGT013038 Histone acetyltransferase p300 reviewed - EP300 Inhibition '<=' 20 %
Q92993 BXGT019403 Histone acetyltransferase KAT5 reviewed - KAT5 IC50 '=' 374590 nM
Q92831 BXGT019380 Histone acetyltransferase KAT2B reviewed - KAT2B IC50 '=' 667050 nM
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Activity - - -
Q92993 BXGT019403 Histone acetyltransferase KAT5 reviewed - KAT5 Inhibition '>' 76 %
O14965 BXGT004117 Aurora kinase A reviewed Kinase AURKA Ka '=' 5 /uM
Q92831 BXGT019380 Histone acetyltransferase KAT2B reviewed - KAT2B Inhibition '<=' 20 %
Q92993 BXGT019403 Histone acetyltransferase KAT5 reviewed - KAT5 Inhibition '>' 50 %
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 ID50 '=' 4 mM
O14965 BXGT004117 Aurora kinase A reviewed Kinase AURKA Kcat/Km '=' 6 /s/mM
P08170 BXGT006736 Seed linoleate 13S-lipoxygenase-1 reviewed - LOX1.1 IC50 '>' 250000 nM
P22513 BXGT008777 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal reviewed - Ki '=' 6000 nM
P13661 BXGT007939 Beta-lactamase OXA-1 reviewed - bla IC50 '=' 25000 ug.mL-1
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 ID50 '=' 1 mM
P30897 BXGT009479 Beta-lactamase reviewed - blaP IC50 '=' 31000 ug.mL-1
Q92831 BXGT019380 Histone acetyltransferase KAT2B reviewed - KAT2B IC50 '=' 8500 nM
Q92993 BXGT019403 Histone acetyltransferase KAT5 reviewed - KAT5 IC50 '=' 9000 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF01401 Aronia arbutifolia Aronia arbutifolia Medicinal Plant
BXGF01520 Viscaria viscosa Viscaria viscosa Others
BXGF01532 Clibadium mexiae Clibadium mexiae Others
BXGF02469 Discaria serratifolia Discaria serratifolia Others
BXGF05097 Pteris dactylina Pteris dactylina Medicinal Plant
BXGF06172 Pyrostegia venusta Pyrostegia venusta Others
BXGF06324 Justicia hayatai Justicia hayatai Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease