Showing entry for Aurora kinase A


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004117
Protein NameAurora kinase A
Uniport IdO14965
GeneAURKA
Gene Id6790
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.2 Cell growth and death hsa04114 Oocyte meiosis
5. Organismal Systems 5.2 Endocrine system hsa04914 Progesterone-mediated oocyte maturation
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0031145 anaphase-promoting complex-dependent catabolic process
Biological Process GO:0009948 anterior/posterior axis specification
Biological Process GO:0051301 cell division
Biological Process GO:0051642 centrosome localization
Biological Process GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
Biological Process GO:0000086 G2/M transition of mitotic cell cycle
Biological Process GO:0097421 liver regeneration
Biological Process GO:0000278 mitotic cell cycle
Biological Process GO:0007100 mitotic centrosome separation
Biological Process GO:0007052 mitotic spindle organization
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0010972 negative regulation of G2/M transition of mitotic cell cycle
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0032091 negative regulation of protein binding
Biological Process GO:1990138 neuron projection extension
Biological Process GO:0018105 peptidyl-serine phosphorylation
Biological Process GO:0045840 positive regulation of mitotic nuclear division
Biological Process GO:1900195 positive regulation of oocyte maturation
Biological Process GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0071539 protein localization to centrosome
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0046605 regulation of centrosome cycle
Biological Process GO:0032465 regulation of cytokinesis
Biological Process GO:0010389 regulation of G2/M transition of mitotic cell cycle
Biological Process GO:0031647 regulation of protein stability
Biological Process GO:1901796 regulation of signal transduction by p53 class mediator
Biological Process GO:0009611 response to wounding
Biological Process GO:0007057 spindle assembly involved in female meiosis I
Biological Process GO:0007051 spindle organization
Biological Process GO:0006511 ubiquitin-dependent protein catabolic process
molecular function GO:0005524 ATP binding
molecular function GO:0035174 histone serine kinase activity
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0004672 protein kinase activity
molecular function GO:0019901 protein kinase binding
molecular function GO:0004712 protein serine/threonine/tyrosine kinase activity
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0031625 ubiquitin protein ligase binding
cellular component GO:0043203 axon hillock
cellular component GO:0005814 centriole
cellular component GO:0005813 centrosome
cellular component GO:0032133 chromosome passenger complex
cellular component GO:0005929 cilium
cellular component GO:0000780 condensed nuclear chromosome, centromeric region
cellular component GO:0005829 cytosol
cellular component GO:0042585 germinal vesicle
cellular component GO:0072687 meiotic spindle
cellular component GO:0005874 microtubule
cellular component GO:0015630 microtubule cytoskeleton
cellular component GO:0030496 midbody
cellular component GO:0097431 mitotic spindle pole
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0045120 pronucleus
cellular component GO:0005819 spindle
cellular component GO:0051233 spindle midzone
cellular component GO:0031616 spindle pole centrosome
Reactome
Pathway Id Pathway Name
R-HSA-1640170 Cell Cycle
R-HSA-174143 APC/C-mediated degradation of cell cycle proteins
R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
R-HSA-212436 Generic Transcription Pathway
R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition
R-HSA-2990846 SUMOylation
R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins
R-HSA-3700989 Transcriptional Regulation by TP53
R-HSA-392499 Metabolism of proteins
R-HSA-453274 Mitotic G2-G2/M phases
R-HSA-453276 Regulation of mitotic cell cycle
R-HSA-4615885 SUMOylation of DNA replication proteins
R-HSA-5633007 Regulation of TP53 Activity
R-HSA-597592 Post-translational protein modification
R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes
R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation
R-HSA-69275 G2/M Transition
R-HSA-69278 Cell Cycle, Mitotic
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
R-HSA-8854518 AURKA Activation by TPX2
R-HSA-8854521 Interaction between PHLDA1 and AURKA
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001430 BXGD000054 Adenoma Neoplasms
C0001815 BXGD000078 Primary Myelofibrosis Hemic and Lymphatic Diseases
C0002938 BXGD000155 Aneuploidy Pathological Conditions, Signs and Symptoms
C0003130 BXGD000183 Anoxia Pathological Conditions, Signs and Symptoms
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007112 BXGD000429 Adenocarcinoma of prostate Neoplasms; Male Urogenital Diseases
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007124 BXGD000437 Noninfiltrating Intraductal Carcinoma Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007138 BXGD000446 Carcinoma, Transitional Cell Neoplasms
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008626 BXGD000559 Congenital chromosomal disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0009405 BXGD000607 Hereditary Nonpolyposis Colorectal Neoplasms Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Nutritional and Metabolic Diseases
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0017185 BXGD001104 Gastrointestinal Neoplasms Digestive System Diseases; Neoplasms
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0018133 BXGD001176 Graft-vs-Host Disease Immune System Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019562 BXGD001336 Von Hippel-Lindau Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Cardiovascular Diseases
C0022665 BXGD001573 Kidney Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023461 BXGD001653 Leukemia, Mast-Cell Neoplasms
C0023462 BXGD001654 Acute Megakaryocytic Leukemias Neoplasms
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023827 BXGD001707 liposarcoma Neoplasms
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024143 BXGD001741 Lupus Nephritis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases; Immune System Diseases
C0024232 BXGD001751 Lymphatic Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024305 BXGD001763 Lymphoma, Non-Hodgkin Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024419 BXGD001769 Waldenstrom Macroglobulinemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0024668 BXGD001795 Mammary Neoplasms, Experimental Neoplasms
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025500 BXGD001874 Mesothelioma Neoplasms
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026470 BXGD001903 Monoclonal Gammopathy of Undetermined Significance Immune System Diseases; Hemic and Lymphatic Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026987 BXGD001957 Myelofibrosis Pathological Conditions, Signs and Symptoms; Neoplasms; Hemic and Lymphatic Diseases
C0027022 BXGD001962 Myeloproliferative disease Hemic and Lymphatic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027830 BXGD002046 neurofibroma Neoplasms; Nervous System Diseases
C0027831 BXGD002047 Neurofibromatosis 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0028259 BXGD002073 Nodule
C0028945 BXGD002099 oligodendroglioma Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0030354 BXGD002214 Papilloma Neoplasms
C0032927 BXGD002381 Precancerous Conditions Neoplasms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0034951 BXGD002498 Refractive Errors Eye Diseases
C0035220 BXGD002512 Respiratory Distress Syndrome, Newborn Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0035369 BXGD002543 Retroviridae Infections Infections
C0035920 BXGD002570 Rubella Infections
C0036631 BXGD002626 Seminoma Neoplasms
C0037286 BXGD002681 Skin Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0042138 BXGD002962 Uterine Neoplasms Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079773 BXGD003100 Lymphoma, T-Cell, Cutaneous Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085136 BXGD003131 Central Nervous System Neoplasms Neoplasms; Nervous System Diseases
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0153567 BXGD003665 Uterine Cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0162678 BXGD003974 Neurofibromatoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0205851 BXGD004132 Germ cell tumor Neoplasms
C0206708 BXGD004256 Cervical Intraepithelial Neoplasia Neoplasms
C0206731 BXGD004276 Angiofibroma Neoplasms
C0220605 BXGD004294 Adult Non-Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220612 BXGD004296 Childhood Non-Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220615 BXGD004298 Adult Acute Myeloblastic Leukemia Neoplasms
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0220650 BXGD004310 Metastatic malignant neoplasm to brain Pathological Conditions, Signs and Symptoms; Neoplasms; Nervous System Diseases
C0221023 BXGD004369 Cyclic neutropenia Hemic and Lymphatic Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0262584 BXGD005256 Carcinoma, Small Cell Neoplasms
C0265344 BXGD005527 Donohue Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Endocrine System Diseases
C0268398 BXGD005933 Familial lichen amyloidosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0271084 BXGD006159 Exudative age-related macular degeneration Eye Diseases
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278608 BXGD006549 Adult Liposarcoma Neoplasms
C0278622 BXGD006551 Adult Malignant Peripheral Nerve Sheath Tumor Neoplasms; Nervous System Diseases
C0278678 BXGD006556 Metastatic Renal Cell Cancer
C0278704 BXGD006567 Malignant Childhood Neoplasm Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279628 BXGD006659 Adenocarcinoma Of Esophagus Digestive System Diseases; Neoplasms
C0279629 BXGD006660 Adult Acute Monoblastic Leukemia Neoplasms
C0279645 BXGD006669 Childhood Acute Monoblastic Leukemia
C0279671 BXGD006677 Cervical Squamous Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0279984 BXGD006703 Childhood Liposarcoma Neoplasms
C0279987 BXGD006706 Childhood Malignant Peripheral Nerve Sheath Tumor Neoplasms; Nervous System Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280324 BXGD006740 Laryngeal Squamous Cell Carcinoma Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0280630 BXGD006751 Uterine Carcinosarcoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0282612 BXGD006820 Prostatic Intraepithelial Neoplasias Neoplasms
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0334634 BXGD007144 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0375023 BXGD007970 Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0457334 BXGD008888 Acute monoblastic leukemia Neoplasms
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0521158 BXGD009130 Recurrent tumor
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0595989 BXGD009632 Carcinoma of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677730 BXGD009727 Aggressive Adult Non-Hodgkin Lymphoma
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0677898 BXGD009735 invasive cancer Neoplasms
C0677936 BXGD009737 Refractory cancer Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0685938 BXGD009829 Malignant neoplasm of gastrointestinal tract Digestive System Diseases; Neoplasms
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0730328 BXGD009959 Central Serous Chorioretinopathy Eye Diseases
C0740457 BXGD010000 Malignant neoplasm of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0751396 BXGD010425 Well Differentiated Oligodendroglioma Neoplasms
C0751688 BXGD010551 Malignant Squamous Cell Neoplasm Neoplasms
C0751690 BXGD010553 Malignant Peripheral Nerve Sheath Tumor Neoplasms; Nervous System Diseases
C0812413 BXGD010847 Malignant Pleural Mesothelioma Neoplasms; Respiratory Tract Diseases
C0854924 BXGD011052 Papillary serous endometrial carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0854985 BXGD011055 Adenocarcinoma of lung, stage I
C0856825 BXGD011118 Acute GVH disease Immune System Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0940937 BXGD011490 precancerous lesions
C1134719 BXGD011688 Invasive Ductal Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1257806 BXGD011808 Chromosomal Instability Pathological Conditions, Signs and Symptoms
C1257931 BXGD011815 Mammary Neoplasms, Human Neoplasms; Skin and Connective Tissue Diseases
C1261473 BXGD011855 Sarcoma Neoplasms
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1269955 BXGD012005 Tumor Cell Invasion
C1292778 BXGD012237 Chronic myeloproliferative disorder Neoplasms; Hemic and Lymphatic Diseases
C1302401 BXGD012303 Adenoma of large intestine Digestive System Diseases; Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1319315 BXGD012415 Adenocarcinoma of large intestine Digestive System Diseases; Neoplasms
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1332225 BXGD012515 Aggressive Non-Hodgkin Lymphoma
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1334274 BXGD012695 Invasive Carcinoma Neoplasms
C1335177 BXGD012771 Ovarian Serous Adenocarcinoma Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1512409 BXGD013188 Hepatocarcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1519346 BXGD013235 Skin Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1608408 BXGD013434 Malignant transformation
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1704376 BXGD013552 Uterine Corpus Carcinosarcoma
C1707444 BXGD013586 Columnar Cell Change of the Breast
C1708350 BXGD013598 Hereditary Leiomyomatosis and Renal Cell Cancer Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C1739135 BXGD013733 Progression of prostate cancer
C1827293 BXGD013768 Carcinoma of urinary bladder, invasive Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1851841 BXGD015242 ECTRODACTYLY, ECTODERMAL DYSPLASIA, AND CLEFT LIP/PALATE SYNDROME 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Stomatognathic Diseases
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2145472 BXGD016931 Urothelial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2347761 BXGD017049 Childhood Myelodysplastic Syndrome Hemic and Lymphatic Diseases
C2938924 BXGD018167 Oestrogen receptor positive breast cancer
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3160889 BXGD018491 Node-negative breast cancer
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3544205 BXGD019109 Ovarian clear cell carcinoma
C3642347 BXGD019246 Basal-Like Breast Carcinoma
C3839280 BXGD019772 High grade serous carcinoma
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C3900098 BXGD020106 Adult Myelodysplastic Syndrome Hemic and Lymphatic Diseases
C4016820 BXGD020379 COLON CANCER, SUSCEPTIBILITY TO
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4086152 BXGD022123 Childhood Astrocytoma Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4524268 BXGD023104 Advanced lung cancer
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
C4704874 BXGD023682 Mammary Carcinoma, Human Neoplasms; Skin and Connective Tissue Diseases
C4721413 BXGD023737 Juvenile angiofibroma Neoplasms; Cardiovascular Diseases
C4721414 BXGD023738 Mantle cell lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
C4721532 BXGD023752 Lymphoma, Non-Hodgkin, Familial Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4721579 BXGD023759 Secondary malignant neoplasm of colon and/or rectum Digestive System Diseases; Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4721698 BXGD023763 Metastatic Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722419 BXGD023802 Extrapulmonary Small Cell Carcinoma Neoplasms
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4725076 BXGD023827 Advanced Urothelial Carcinoma
C4725671 BXGD023833 High-Risk Neuroblastoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0001026 Eupatorin 344.32
BXGC0002063 Alternariol 258.23
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
BXGC0002605 Adenosine 267.24
BXGC0002692 Arsenic 77.95
BXGC0003705 Chloride 35.45
BXGC0004115 Norharman 168.19
BXGC0004580 Carbanilide 212.25
BXGC0004705 Diphenylamine 169.22
BXGC0006193 Ellagic acid 302.19
BXGC0006198 Citric acid 192.12
BXGC0012352 Chelerythrine 348.12
BXGC0017701 Altenusin 290.08
BXGC0017933 Sulfuretin 270.05
BXGC0023872 Adenine 135.05
BXGC0024070 Anacardic Acid 342.22
BXGC0024554 D-luciferin 280
BXGC0030612 tetraethylene glycol 194.12
BXGC0034783 Doxorubicin 543.17
BXGC0035685 alternariol monomethyl ether 272.07
BXGC0037687 (4S)-2-methylpentane-2,4-diol 118.1
BXGC0038007 Aristolactam Aiiia 281.07
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
BXGC0049447 acetate 59.01
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
BXGC0051819 Altertoxin I 352.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein