acompound

Showing entry for Benzidine

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0025066
Compound Name	Benzidine
Structure
Formula	C12H12N2
InchiKey	HFACYLZERDEVSX-UHFFFAOYSA-N
SMILES	Nc1ccc(cc1)c1ccc(cc1)N
Inchi	InChI=1S/C12H12N2/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10/h1-8H,13-14H2
IUPAC	4-(4-aminophenyl)aniline
Molecular Weight	184.1
Pubchem Id	7111
Chembl Id	CHEMBL15901

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	Potency	'='	25118	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	'='	50118	nM
Q9R1A7	BXGT021413	Nuclear receptor subfamily 1 group I member 2	reviewed	-	Nr1i2	Potency	-	44668	nM
P10828	BXGT007624	Thyroid hormone receptor beta	reviewed	Nuclear receptor	THRB	Potency	-	44668	nM
P35503	BXGT009840	UDP-glucuronosyltransferase 1-3	reviewed	-	UGT1A3	Activity	'='	5	pm/min/mg
P22310	BXGT008754	UDP-glucuronosyltransferase 1-4	reviewed	-	UGT1A4	Km	'='	460000	nM
P04637	BXGT006243	Cellular tumor antigen p53	reviewed	Transcription factor	TP53	Potency	'='	7	nM
P00352	BXGT005510	Retinal dehydrogenase 1	reviewed	Enzyme	ALDH1A1	Potency	'='	35481	nM
P22310	BXGT008754	UDP-glucuronosyltransferase 1-4	reviewed	-	UGT1A4	Activity	'='	240	pm/min/mg
P22310	BXGT008754	UDP-glucuronosyltransferase 1-4	reviewed	-	UGT1A4	Activity	'='	204	pm/min/mg
O94925	BXGT005342	Glutaminase kidney isoform, mitochondrial	reviewed	Enzyme	GLS	Potency	-	19952	nM
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	reviewed	-	GNAS	Potency	-	19952	nM
Q9H0H5	BXGT020436	Rac GTPase-activating protein 1	reviewed	Enzyme modulator	RACGAP1	IC50	-	7390	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00040	Pepper (C. annuum)	Capsicum annuum	Vegetables
BXGF00522	Narrowleaf cattail	Typha angustifolia	Vegetables
BXGF04600	Typha orientalis	Typha orientalis	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}