acompound

Showing entry for 2'-hydroxyflavone

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0025368
Compound Name	2'-hydroxyflavone
Structure
Formula	C15H10O3
InchiKey	ZZLQHXCRRMUGQJ-UHFFFAOYSA-N
SMILES	Oc1ccccc1c1cc(=O)c2c(o1)cccc2
Inchi	InChI=1S/C15H10O3/c16-12-7-3-1-5-10(12)15-9-13(17)11-6-2-4-8-14(11)18-15/h1-9,16H
IUPAC	2-(2-hydroxyphenyl)chromen-4-one
Molecular Weight	238.06
Pubchem Id	161860
Chembl Id	CHEMBL144278

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT008644	Amine oxidase [flavin-containing] A	reviewed		MAOA	520	-	-	-
reviewed	BXGT009172	Amine oxidase [flavin-containing] B	reviewed		MAOB	5980	-	-	-
reviewed	BXGT010301	Aldo-keto reductase family 1 member C3	reviewed	Enzyme	AKR1C3	-	300	-	-
reviewed	BXGT010961	Aldo-keto reductase family 1 member C2	reviewed	Enzyme	AKR1C2	-	47100	-	-
reviewed	BXGT012787	Aldo-keto reductase family 1 member C1	reviewed	Enzyme	AKR1C1	-	6200	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P42330	BXGT010301	Aldo-keto reductase family 1 member C3	reviewed	Enzyme	AKR1C3	IC50	'='	300	nM
P52895	BXGT010961	Aldo-keto reductase family 1 member C2	reviewed	Enzyme	AKR1C2	IC50	'='	47100	nM
Q04828	BXGT012787	Aldo-keto reductase family 1 member C1	reviewed	Enzyme	AKR1C1	IC50	'='	6200	nM
P10275	BXGT007552	Androgen receptor	reviewed	Nuclear receptor	AR	IC50	'>'	10000	nM
P10275	BXGT007552	Androgen receptor	reviewed	Nuclear receptor	AR	IC50	'<'	1000	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00046	Roman camomile	Chamaemelum nobile	Herbs and Spices
BXGF02518	Schkuhria multiflora	Schkuhria multiflora	Others
BXGF03734	Anthocleista grandiflora	Anthocleista grandiflora	Medicinal Plant
BXGF03743	Helleborus caucasicus	Helleborus caucasicus	Others
BXGF03758	Lespedeza homoloba	Lespedeza homoloba	Medicinal Plant
BXGF03780	Lolium perenne	Lolium perenne	Medicinal Plant
BXGF03793	Hypoestes serpens	Hypoestes serpens	Medicinal Plant
BXGF03806	Primula farinosa	Primula farinosa	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}