acompound

Showing entry for Norathyriol

General Compound Information
BXGC Id	BXGC0025529
Compound Name	Norathyriol
Structure
Formula	C13H8O6
InchiKey	ZHTQCPCDXKMMLU-UHFFFAOYSA-N
SMILES	Oc1cc(O)c2c(c1)oc1c(c2=O)cc(c(c1)O)O
Inchi	InChI=1S/C13H8O6/c14-5-1-9(17)12-11(2-5)19-10-4-8(16)7(15)3-6(10)13(12)18/h1-4,14-17H
IUPAC	1,3,6,7-tetrahydroxyxanthen-9-one
Molecular Weight	260.03
Pubchem Id	5281656
Chembl Id	CHEMBL187265

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

NRA

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P28482	BXGT009263	Mitogen-activated protein kinase 1	reviewed	MAPK1	Kinase	-	-	-	-

Binding DB

50155447

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT010694	Fatty acid synthase	reviewed	Enzyme	FASN	-	17850	-	-
reviewed	BXGT008644	Amine oxidase [flavin-containing] A	reviewed		MAOA	-	25000	-	-
reviewed	BXGT007849	Angiotensin-converting enzyme	reviewed	Enzyme	ACE	-	530800	-	-
reviewed	BXGT007849	Angiotensin-converting enzyme	reviewed	Enzyme	ACE	250200	-	-	-
reviewed	BXGT011911	Xanthine dehydrogenase/oxidase	reviewed		XDH	-	21730	-	-
reviewed	BXGT006120	Interstitial collagenase	reviewed	Enzyme	MMP1	-	11360	-	-

CHEMBL

CHEMBL187265

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P45452	BXGT010462	Collagenase 3	reviewed	Enzyme	MMP13	IC50	-	-	-
P03956	BXGT006120	Interstitial collagenase	reviewed	Enzyme	MMP1	IC50	'='	11360	nM
P12821	BXGT007849	Angiotensin-converting enzyme	reviewed	Enzyme	ACE	Inhibition	'='	23	%
P49327	BXGT010694	Fatty acid synthase	reviewed	Enzyme	FASN	IC50	'='	17850	nM
P08253	BXGT006757	72 kDa type IV collagenase	reviewed	Enzyme	MMP2	IC50	-	-	-
P80457	BXGT011911	Xanthine dehydrogenase/oxidase	reviewed	-	XDH	IC50	'='	21730	nM
P12821	BXGT007849	Angiotensin-converting enzyme	reviewed	Enzyme	ACE	Ki	'='	250200	nM
P21397	BXGT008644	Amine oxidase [flavin-containing] A	reviewed	-	MAOA	IC50	'='	25000	nM
P14780	BXGT008053	Matrix metalloproteinase-9	reviewed	Enzyme	MMP9	IC50	-	-	-
P12821	BXGT007849	Angiotensin-converting enzyme	reviewed	Enzyme	ACE	IC50	'='	530800	nM
P08254	BXGT006758	Stromelysin-1	reviewed	Enzyme	MMP3	IC50	-	-	-
P03956	BXGT006120	Interstitial collagenase	reviewed	Enzyme	MMP1	Inhibition	'>'	30	%
P12821	BXGT007849	Angiotensin-converting enzyme	reviewed	Enzyme	ACE	Inhibition	'='	15	%
P39900	BXGT010148	Macrophage metalloelastase	reviewed	Enzyme	MMP12	IC50	-	-	-
P12821	BXGT007849	Angiotensin-converting enzyme	reviewed	Enzyme	ACE	Inhibition	'='	40	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00063	Saffron	Crocus sativus	Herbs and Spices
BXGF00093	Black walnut	Juglans nigra	Nuts
BXGF00106	Mango	Mangifera indica	Fruits
BXGF00369	Sacred lotus	Nelumbo nucifera	Vegetables
BXGF00373	Purple mangosteen	Garcinia mangostana	Fruits
BXGF00864	Nicotiana sylvestris	Nicotiana sylvestris	Others
BXGF00927	Dolomiaea souliei	Dolomiaea souliei	Others
BXGF00962	Machilus thunbergii	Machilus thunbergii	Medicinal Plant
BXGF01007	Eucalyptus camaldulensis	Eucalyptus camaldulensis	Medicinal Plant
BXGF01149	Garcinia oblongifolia	Garcinia oblongifolia	Human Edible Plant
BXGF01175	Neomeris annulata	Neomeris annulata	Others
BXGF01639	Mangifera persiciformis	Mangifera persiciformis	Medicinal Plant
BXGF01708	Narcissus concolor	Narcissus concolor	Others
BXGF01856	Aquilaria sinensis	Aquilaria sinensis	Medicinal Plant
BXGF01883	Swertia franchetiana	Swertia franchetiana	Medicinal Plant
BXGF02251	Pyrrosia lingua	Pyrrosia lingua	Medicinal Plant
BXGF02715	Pyrrosia davidii	Pyrrosia davidii	Human Edible Plant
BXGF03479	Bombax ceiba	Bombax ceiba	Medicinal Plant
BXGF03762	Pyrrosia petiolosa	Pyrrosia petiolosa	Medicinal Plant
BXGF03981	Senecio vellereus	Senecio vellereus	Others
BXGF04116	Tripterospermum lanceolatum	Tripterospermum lanceolatum	Others
BXGF04177	Cordylanthus kingii	Cordylanthus kingii	Others
BXGF04213	Trifolium resupinatum	Trifolium resupinatum	Agricultural Plant
BXGF04303	Anemarrhena asphodeloides	Anemarrhena asphodeloides	Medicinal Plant
BXGF04401	Annona impressivenia	Annona impressivenia	Others
BXGF04519	Serpocaulon triseriale	Serpocaulon triseriale	Others
BXGF04728	Alseodaphne corneri	Alseodaphne corneri	Others
BXGF04730	Thymus piperella	Thymus piperella	Human Edible Plant
BXGF04739	Forsteronia refracta	Forsteronia refracta	Others
BXGF04742	Eragrostis viscosa	Eragrostis viscosa	Medicinal Plant
BXGF04747	Nauclea officinalis	Nauclea officinalis	Medicinal Plant
BXGF04753	Grewia mollis	Grewia mollis	Medicinal Plant
BXGF04765	Heterotheca grandiflora	Heterotheca grandiflora	Others
BXGF04771	Croton cumingii	Croton cumingii	Medicinal Plant
BXGF04775	Bersama yangambiensis	Bersama yangambiensis	Others
BXGF04783	Ruta pinnata	Ruta pinnata	Medicinal Plant
BXGF04795	Disynaphia halimifolia	Disynaphia halimifolia	Others
BXGF04821	Kaunia saltensis	Kaunia saltensis	Others
BXGF04826	Heliotropium floridum	Heliotropium floridum	Others
BXGF04835	Castanopsis sclerophylla	Castanopsis sclerophylla	Medicinal Plant
BXGF04839	Gymnocarpium robertianum	Gymnocarpium robertianum	Others
BXGF04846	Oncoba echinata	Oncoba echinata	Others
BXGF04851	Salvia dorrii	Salvia dorrii	Others
BXGF04858	Teucrium depressum	Teucrium depressum	Others
BXGF04866	Aconitum nevadense	Aconitum nevadense	Others
BXGF04871	Trichilia rubescens	Trichilia rubescens	Others
BXGF04874	Conocephalum japonicum	Conocephalum japonicum	Others
BXGF04880	Hovenia acerba	Hovenia acerba	Medicinal Plant
BXGF04885	Stevia polycephala	Stevia polycephala	Others
BXGF04893	Sophora angustifolia	Sophora angustifolia	Others
BXGF04898	Urena lobata	Urena lobata	Medicinal Plant
BXGF04901	Kaempferia marginata	Kaempferia marginata	Medicinal Plant
BXGF05033	garcinia esculenta	garcinia esculenta	Human Edible Plant
BXGF05064	Fridericia chica	Fridericia chica	Medicinal Plant
BXGF05090	Lonicera hypoleuca	Lonicera hypoleuca	Human Edible Plant
BXGF05157	Garcinia morella	Garcinia morella	Medicinal Plant
BXGF05213	Halimodendron halodendron	Halimodendron halodendron	Others
BXGF05245	Doodia picta	Doodia picta	Others
BXGF05269	Hypericum perforatum	Hypericum perforatum	Medicinal Plant
BXGF05387	Garcinia multiflora	Garcinia multiflora	Medicinal Plant
BXGF05434	Zanthoxylum decaryi	Zanthoxylum decaryi	Medicinal Plant
BXGF05715	Cistanche salsa	Cistanche salsa	Medicinal Plant
BXGF05857	Iris domestica	Iris domestica	Medicinal Plant
BXGF06008	Aster bellidiastrum	Aster bellidiastrum	Others
BXGF06188	Swertia mussotii	Swertia mussotii	Medicinal Plant
BXGF06189	Piper wightii	Piper wightii	Others
BXGF06276	Wibelia divaricata	Wibelia divaricata	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}