Showing entry for Collagenase 3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010462
Protein NameCollagenase 3
Uniport IdP45452
GeneMMP13
Gene Id4322
DomainHemopexin; Peptidase_M10; PG_binding_1
Pfam PF00045   PF00413   PF01471  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.1 Immune system hsa04657 IL-17 signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04926 Relaxin signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030282 bone mineralization
Biological Process GO:0060349 bone morphogenesis
Biological Process GO:0044267 cellular protein metabolic process
Biological Process GO:0030574 collagen catabolic process
Biological Process GO:0001958 endochondral ossification
Biological Process GO:0022617 extracellular matrix disassembly
Biological Process GO:0030198 extracellular matrix organization
Biological Process GO:0003417 growth plate cartilage development
Biological Process GO:0006508 proteolysis
Biological Process GO:1904645 response to amyloid-beta
molecular function GO:0005509 calcium ion binding
molecular function GO:0005518 collagen binding
molecular function GO:0004175 endopeptidase activity
molecular function GO:0004222 metalloendopeptidase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0031012 extracellular matrix
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
Reactome
Pathway Id Pathway Name
R-HSA-1442490 Collagen degradation
R-HSA-1442490 Collagen degradation
R-HSA-1474228 Degradation of the extracellular matrix
R-HSA-1474228 Degradation of the extracellular matrix
R-HSA-1474244 Extracellular matrix organization
R-HSA-1474244 Extracellular matrix organization
R-HSA-1474290 Collagen formation
R-HSA-1592389 Activation of Matrix Metalloproteinases
R-HSA-2022090 Assembly of collagen fibrils and other multimeric structures
R-HSA-212436 Generic Transcription Pathway
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-8878166 Transcriptional regulation by RUNX2
R-HSA-8941332 RUNX2 regulates genes involved in cell migration
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0000846 BXGD000015 Agenesis
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001815 BXGD000078 Primary Myelofibrosis Hemic and Lymphatic Diseases
C0002382 BXGD000109 Alveolar Bone Loss Musculoskeletal Diseases; Stomatognathic Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003504 BXGD000202 Aortic Valve Insufficiency Cardiovascular Diseases
C0003507 BXGD000203 Aortic Valve Stenosis Cardiovascular Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004763 BXGD000289 Barrett Esophagus Digestive System Diseases; Neoplasms
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005937 BXGD000350 Bone Cysts Neoplasms; Musculoskeletal Diseases
C0005940 BXGD000352 Bone Diseases Musculoskeletal Diseases
C0006079 BXGD000365 Bowen's Disease Neoplasms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007124 BXGD000437 Noninfiltrating Intraductal Carcinoma Neoplasms
C0007130 BXGD000440 Mucinous Adenocarcinoma Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007138 BXGD000446 Carcinoma, Transitional Cell Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007786 BXGD000486 Brain Ischemia Nervous System Diseases; Cardiovascular Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008312 BXGD000527 Primary biliary cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0008479 BXGD000544 Chondrosarcoma Neoplasms
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010709 BXGD000689 Cyst Pathological Conditions, Signs and Symptoms; Neoplasms
C0011334 BXGD000716 Dental caries Stomatognathic Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0012813 BXGD000791 Diverticulitis Digestive System Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0014170 BXGD000902 Endometrial Neoplasms Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015302 BXGD000974 External exotoses Musculoskeletal Diseases
C0016057 BXGD001042 Fibrosarcoma Neoplasms
C0017574 BXGD001122 Gingivitis Infections; Stomatognathic Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021818 BXGD001514 Intervertebral Disk Displacement Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0022408 BXGD001544 Arthropathy Musculoskeletal Diseases
C0022548 BXGD001551 Keloid Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0022572 BXGD001553 keratoacanthoma Skin and Connective Tissue Diseases
C0023051 BXGD001602 Laryngeal Diseases Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0023531 BXGD001684 Leukoplakia Pathological Conditions, Signs and Symptoms; Neoplasms
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023891 BXGD001714 Liver Cirrhosis, Alcoholic Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Chemically-Induced Disorders
C0023892 BXGD001715 Biliary cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0024003 BXGD001726 Lordosis Musculoskeletal Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024198 BXGD001743 Lyme Disease Infections
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0024796 BXGD001806 Marfan Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Cardiovascular Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0025294 BXGD001854 Meningococcal meningitis Infections; Nervous System Diseases
C0026618 BXGD001909 Dental Fluorosis, Acquired Stomatognathic Diseases
C0026640 BXGD001912 Mouth Neoplasms Neoplasms; Stomatognathic Diseases
C0026691 BXGD001917 Mucocutaneous Lymph Node Syndrome Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027830 BXGD002046 neurofibroma Neoplasms; Nervous System Diseases
C0027831 BXGD002047 Neurofibromatosis 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029410 BXGD002138 Osteoarthritis of hip Musculoskeletal Diseases
C0029421 BXGD002141 Osteochondritis Dissecans Musculoskeletal Diseases
C0029443 BXGD002152 Osteomyelitis Infections; Musculoskeletal Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0031029 BXGD002271 Periapical Granuloma Stomatognathic Diseases
C0031090 BXGD002280 Periodontal Diseases Stomatognathic Diseases
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0032131 BXGD002330 Plasmacytoma Neoplasms; Immune System Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0034543 BXGD002483 Radicular Cyst Neoplasms; Musculoskeletal Diseases; Stomatognathic Diseases
C0035579 BXGD002560 Rickets Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0036220 BXGD002587 Kaposi Sarcoma Neoplasms; Infections
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037116 BXGD002666 Silicosis Respiratory Tract Diseases; Occupational Diseases
C0038220 BXGD002740 Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038358 BXGD002748 Gastric ulcer Digestive System Diseases
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0039103 BXGD002791 Synovitis Musculoskeletal Diseases
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0041330 BXGD002917 Tuberculosis, Spinal Infections; Musculoskeletal Diseases
C0042344 BXGD002976 Varicose Ulcer Skin and Connective Tissue Diseases; Cardiovascular Diseases
C0042345 BXGD002977 Varicosity Cardiovascular Diseases
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0042870 BXGD003008 Vitamin D Deficiency Nutritional and Metabolic Diseases
C0079293 BXGD003069 Epidermolysis Bullosa Acquisita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0079474 BXGD003077 Hallopeau-Siemens Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085109 BXGD003125 Corneal Neovascularization Pathological Conditions, Signs and Symptoms; Eye Diseases
C0085110 BXGD003126 Severe Combined Immunodeficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C0086692 BXGD003306 Benign Neoplasm Neoplasms
C0149521 BXGD003328 Pancreatitis, Chronic Digestive System Diseases
C0151650 BXGD003454 Renal fibrosis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0151936 BXGD003505 Disorder of tendon Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0153690 BXGD003684 Secondary malignant neoplasm of bone Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0155072 BXGD003768 Mooren's ulcer Infections; Eye Diseases
C0157946 BXGD003873 Osteoarthrosis, localized, not specified whether primary or secondary Musculoskeletal Diseases
C0158252 BXGD003877 Intervertebral disc disorder Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0158266 BXGD003878 Intervertebral Disc Degeneration Musculoskeletal Diseases
C0158646 BXGD003897 Cleft palate with cleft lip Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0162298 BXGD003933 Joint stiffness Musculoskeletal Diseases
C0162678 BXGD003974 Neurofibromatoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0162810 BXGD003982 Cicatrix, Hypertrophic Pathological Conditions, Signs and Symptoms
C0162871 BXGD003996 Aortic Aneurysm, Abdominal Cardiovascular Diseases
C0178664 BXGD004032 Glomerulosclerosis (disorder) Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Cardiovascular Diseases
C0202117 BXGD004074 Low density lipoprotein cholesterol measurement
C0202236 BXGD004086 Triglycerides measurement
C0205622 BXGD004092 Microinvasive tumor
C0205748 BXGD004117 Dysplastic Nevus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
C0206638 BXGD004203 Giant Cell Tumor of Bone Neoplasms
C0206650 BXGD004214 Fibroadenoma Neoplasms
C0206677 BXGD004234 Adenomatous Polyps Neoplasms
C0206696 BXGD004247 Carcinoma, Signet Ring Cell Neoplasms
C0206727 BXGD004272 Nerve Sheath Tumors Neoplasms; Nervous System Diseases
C0220620 BXGD004299 Gastrointestinal Carcinoid Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0221775 BXGD004480 Lumbar disc disease Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0231586 BXGD004501 Joint function disorder
C0231712 BXGD004519 Waddling gait Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0232197 BXGD004536 Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0234985 BXGD004708 Mental deterioration Mental Disorders
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238461 BXGD004936 Anaplastic thyroid carcinoma Neoplasms
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0238790 BXGD004956 bone destruction
C0239138 BXGD004966 Hip joint varus deformity - observation Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242362 BXGD005155 Disk, Herniated Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0263630 BXGD005335 Hypertrophic disorder of skin, unspecified Skin and Connective Tissue Diseases
C0263874 BXGD005352 Degeneration of lumbar intervertebral disc Musculoskeletal Diseases
C0265289 BXGD005502 Metaphyseal chondrodysplasia Schmid type Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0265290 BXGD005503 Metaphyseal chondrodysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0271862 BXGD006273 Idiopathic parathyroidism Endocrine System Diseases
C0278488 BXGD006515 Carcinoma breast stage IV
C0278595 BXGD006545 Adult Fibrosarcoma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279680 BXGD006680 Transitional cell carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280313 BXGD006737 Squamous cell carcinoma of oropharynx Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0280324 BXGD006740 Laryngeal Squamous Cell Carcinoma Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0333297 BXGD006945 Chronic ulcer Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Skin and Connective Tissue Diseases
C0333307 BXGD006946 Superficial ulcer Pathological Conditions, Signs and Symptoms
C0333519 BXGD006958 Caries (morphologic abnormality) Pathological Conditions, Signs and Symptoms
C0334424 BXGD007064 Nodular melanoma Neoplasms; Skin and Connective Tissue Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0341038 BXGD007385 Jaw Keratocyst Neoplasms; Musculoskeletal Diseases; Stomatognathic Diseases
C0345958 BXGD007751 Large cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349489 BXGD007911 Fetal Hypoxia Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0349588 BXGD007933 Short stature
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376634 BXGD008006 Craniofacial Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0391826 BXGD008013 Lhermitte-Duclos disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
C0392885 BXGD008071 High density lipoprotein measurement
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0409952 BXGD008399 Idiopathic osteoarthritis Musculoskeletal Diseases
C0409959 BXGD008400 Osteoarthritis, Knee Musculoskeletal Diseases
C0410606 BXGD008437 Cervical Disc Degenerative Disorder Musculoskeletal Diseases
C0426901 BXGD008597 Short leg
C0428472 BXGD008630 Serum HDL cholesterol measurement
C0428474 BXGD008631 Serum LDL cholesterol measurement
C0432211 BXGD008737 Spondyloepimetaphyseal disorder Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0432225 BXGD008743 Metaphyseal chondrodysplasia Spahr type Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0432226 BXGD008744 Metaphyseal anadysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0520463 BXGD009085 Chronic active hepatitis Digestive System Diseases
C0520947 BXGD009126 Clumsiness - motor delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0541764 BXGD009259 Delayed bone age
C0544755 BXGD009310 Genu varum Musculoskeletal Diseases
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0553694 BXGD009409 Oropharyngeal disorders Digestive System Diseases; Respiratory Tract Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0553723 BXGD009416 Squamous cell carcinoma of skin Neoplasms; Skin and Connective Tissue Diseases
C0558353 BXGD009451 Tongue Carcinoma Neoplasms; Stomatognathic Diseases
C0559470 BXGD009471 Allergy to peanuts Immune System Diseases
C0575081 BXGD009512 Gait abnormality Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0576093 BXGD009525 Knee joint valgus deformity Musculoskeletal Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598608 BXGD009668 Hyperhomocysteinemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0687720 BXGD009844 Central Diabetes Insipidus Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700635 BXGD009897 Strudwick syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0733682 BXGD009968 Hypophosphatemic Rickets, X-Linked Dominant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases
C0747845 BXGD010184 early pregnancy
C0751688 BXGD010551 Malignant Squamous Cell Neoplasm Neoplasms
C0751690 BXGD010553 Malignant Peripheral Nerve Sheath Tumor Neoplasms; Nervous System Diseases
C0795864 BXGD010754 Smith-Magenis syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0850666 BXGD010901 Infection caused by Helicobacter pylori Infections
C0854135 BXGD011002 Pseudomonas aeruginosa infection Infections
C0856738 BXGD011110 Triple vessel disease Cardiovascular Diseases
C0858004 BXGD011168 Influenza A virus infection Infections; Respiratory Tract Diseases
C0876973 BXGD011322 Infectious Lung Disorder Infections; Respiratory Tract Diseases
C0877008 BXGD011325 Enzyme inhibition disorder
C0878659 BXGD011380 Disproportionate short stature Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0917996 BXGD011425 Cerebral Aneurysm Nervous System Diseases; Cardiovascular Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1096086 BXGD011601 Deformity of lower limb
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1168327 BXGD011787 High-Grade Prostatic Intraepithelial Neoplasia Neoplasms; Male Urogenital Diseases
C1260954 BXGD011845 Morphologically altered structure
C1269955 BXGD012005 Tumor Cell Invasion
C1302401 BXGD012303 Adenoma of large intestine Digestive System Diseases; Neoplasms
C1306068 BXGD012354 After-cataract Eye Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1318485 BXGD012394 Liver regeneration disorder Digestive System Diseases
C1328407 BXGD012465 Hip Dysplasia Musculoskeletal Diseases; Wounds and Injuries
C1332271 BXGD012519 Perianal Squamous Intraepithelial Neoplasia
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1335710 BXGD012803 Recurrent Malignant Peripheral Nerve Sheath Tumor Neoplasms; Nervous System Diseases
C1378703 BXGD012933 Renal carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1384584 BXGD012943 Generalized osteoarthritis Musculoskeletal Diseases
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1568272 BXGD013421 Tendinopathy Musculoskeletal Diseases; Wounds and Injuries
C1608408 BXGD013434 Malignant transformation
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1704356 BXGD013549 Enchondroma Neoplasms
C1704436 BXGD013564 Peripheral Arterial Diseases Cardiovascular Diseases
C1719498 BXGD013657 Generalized chronic periodontitis Stomatognathic Diseases
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1837081 BXGD014193 Tibial bowing Musculoskeletal Diseases
C1837082 BXGD014194 Metaphyseal cupping
C1844704 BXGD014665 Platyspondyly
C1846803 BXGD014840 Small epiphyses
C1849039 BXGD014999 Metaphyseal widening
C1850135 BXGD015112 Flared metaphysis
C1854301 BXGD015391 Motor delay Mental Disorders
C1855191 BXGD015471 Progressive leg bowing
C1855340 BXGD015490 Bowing of the long bones
C1857108 BXGD015677 Limitation of joint mobility
C1857527 BXGD015714 Flattened epiphysis
C1859399 BXGD015886 Radial bowing
C1859461 BXGD015895 Femoral bowing Musculoskeletal Diseases
C1861305 BXGD016027 TARSAL-CARPAL COALITION SYNDROME Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1865832 BXGD016341 Spondyloepimetaphyseal Dysplasia, Missouri Type Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1865833 BXGD016342 Flared, irregular rib ends
C1865841 BXGD016343 Flared iliac wings
C1865847 BXGD016344 Ulnar bowing
C1866730 BXGD016419 Rhizomelia
C1866731 BXGD016420 Pear-shaped vertebrae
C1867103 BXGD016438 Limited elbow extension
C1868554 BXGD016505 Irregular sclerotic endplates
C1956089 BXGD016615 Osteophyte Musculoskeletal Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2062441 BXGD016897 Influenza A
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2674432 BXGD017246 Reduced bone mineral density
C2748495 BXGD017589 Metaphyseal Anadysplasia 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C2749463 BXGD017620 Aplasia/Hypoplasia of the radius
C2894027 BXGD017850 Post traumatic osteoarthritis
C2919142 BXGD017867 Short Stature, CTCAE
C2931073 BXGD017952 Collagenopathy, type 2 alpha 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3536984 BXGD019079 Vitamin D-Resistant Rickets, X-Linked Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3552526 BXGD019156 Metaphyseal sclerosis
C3665629 BXGD019297 Dental fluorosis
C3811653 BXGD019662 Experimental Organism Basal Cell Carcinoma Neoplasms
C3826476 BXGD019726 Dental caries in children
C3887524 BXGD019892 Skin Erosion Skin and Connective Tissue Diseases
C3899234 BXGD020076 Experimental Organism Benign Keratoacanthoma
C4016643 BXGD020353 METAPHYSEAL ANADYSPLASIA 1, AUTOSOMAL DOMINANT
C4021611 BXGD020697 Abnormality of epiphysis morphology
C4021812 BXGD020798 Abnormality of the head
C4025424 BXGD021661 Abnormality of ulnar metaphysis
C4025814 BXGD021806 Abnormality of the metaphysis
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4551649 BXGD023382 Congenital Dysplasia Of The Hip Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C4551915 BXGD023441 Gait Disturbance, CTCAE
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4721806 BXGD023772 Carcinoma, Basal Cell Neoplasms
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722419 BXGD023802 Extrapulmonary Small Cell Carcinoma Neoplasms
C4725861 BXGD023840 Metastatic Malignant Neoplasm in the Viscera
C4727169 BXGD023859 Metastatic Gastric Carcinoma
C4727838 BXGD023874 Advanced Melanoma
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000932 (+)-Secoisolariciresinol 362.42
BXGC0002586 Calcium 40.08
BXGC0003004 3-Methylpyridine 93.13
BXGC0003705 Chloride 35.45
BXGC0004178 R-2-Hydroxy-3-methylbutanoic acid 3-Methylbutanoyl 202.25
BXGC0005683 Quercetin 302.24
BXGC0006368 Formic acid 46.03
BXGC0006635 Luteolin 286.24
BXGC0013582 Curcumin 368.13
BXGC0017022 Dimethyl Lithospermate 566.14
BXGC0021396 8(14)-Podocarpen-13-On-18-Oic Acid 276.17
BXGC0021834 Methyl Rosmarinate 374.1
BXGC0023687 (S)-(+)-1,2-Propanediol 76.05
BXGC0024810 curcumin 368.13
BXGC0025529 Norathyriol 260.03
BXGC0039172 Oxyresveratrol 244.07
BXGC0042270 acetohydroxamic acid 75.03
BXGC0043125 Taxifolin 304.06
BXGC0044075 Macrathoin F 530.14
BXGC0048764 Isoacteoside 624.21
BXGC0052080 Daphnodorin F 542.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein