acompound

Showing entry for N-methylpyrrolidone

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0031118
Compound Name	N-methylpyrrolidone
Structure
Formula	C5H9NO
InchiKey	SECXISVLQFMRJM-UHFFFAOYSA-N
SMILES	O=C1CCCN1C
Inchi	InChI=1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3
IUPAC	1-methylpyrrolidin-2-one
Molecular Weight	99.07
Pubchem Id	13387
Chembl Id	CHEMBL12543

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Q8WWQ0	BXGT019003	PH-interacting protein	reviewed	PHIP	Epigenetic regulator	-	-	-	-
Q86U86	BXGT017611	Protein polybromo-1	reviewed	PBRM1	Epigenetic regulator	-	-	-	-
Q92793	BXGT019374	CREB-binding protein	reviewed	CREBBP	-	-	-	-	-
O95696	BXGT005390	Bromodomain-containing protein 1	reviewed	BRD1	-	-	-	-	-
P51532	BXGT010852	Transcription activator BRG1	reviewed	SMARCA4	Epigenetic regulator	-	-	-	-
P25440	BXGT009044	Bromodomain-containing protein 2	reviewed	BRD2	Epigenetic regulator	-	-	-	-
Q6PL18	BXGT016479	ATPase family AAA domain-containing protein 2	reviewed	ATAD2	Epigenetic regulator	-	-	-	-
Q6GHP9	BXGT016307	Cell division protein FtsZ	reviewed	ftsZ	-	-	-	-	-
P0A031	BXGT006961	Cell division protein FtsZ	reviewed	ftsZ	-	-	-	-	-

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT021718	Bromodomain adjacent to zinc finger domain protein 2B	reviewed		BAZ2B	-	34000000	-	-
reviewed	BXGT019374	CREB-binding protein	reviewed		CREBBP	-	2300000	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
O60885	BXGT004906	Bromodomain-containing protein 4	reviewed	Epigenetic regulator	BRD4	IC50	'='	6000000	nM
O60885	BXGT004906	Bromodomain-containing protein 4	reviewed	Epigenetic regulator	BRD4	Inhibition	'<'	5	%
O60885	BXGT004906	Bromodomain-containing protein 4	reviewed	Epigenetic regulator	BRD4	Activity	'<'	5	%
Q15059	BXGT013530	Bromodomain-containing protein 3	reviewed	Epigenetic regulator	BRD3	Inhibition	'<'	5	%
Q15059	BXGT013530	Bromodomain-containing protein 3	reviewed	Epigenetic regulator	BRD3	Activity	'<'	5	%
P25440	BXGT009044	Bromodomain-containing protein 2	reviewed	Epigenetic regulator	BRD2	Inhibition	'<'	5	%
Q92793	BXGT019374	CREB-binding protein	reviewed	-	CREBBP	IC50	'='	2300000	nM
Q9UIF8	BXGT021718	Bromodomain adjacent to zinc finger domain protein 2B	reviewed	-	BAZ2B	IC50	'='	34000000	nM
P25440	BXGT009044	Bromodomain-containing protein 2	reviewed	Epigenetic regulator	BRD2	Activity	'<'	5	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF02906	Garcinia conrauana	Garcinia conrauana	Human Edible Plant
BXGF03141	Achyranthes aspera	Achyranthes aspera	Medicinal Plant
BXGF03237	Morus macroura	Morus macroura	Medicinal Plant
BXGF03330	Sesbania grandiflora	Sesbania grandiflora	Medicinal Plant
BXGF03422	Rhizophora mangle	Rhizophora mangle	Medicinal Plant
BXGF03434	Raphanus raphanistrum	Raphanus raphanistrum	Medicinal Plant
BXGF03460	Microtropis japonica	Microtropis japonica	Others
BXGF03510	Phebalium bilobum	Phebalium bilobum	Others
BXGF03533	Neopringlea integrifolia	Neopringlea integrifolia	Others
BXGF03648	Schisandra sphaerandra	Schisandra sphaerandra	Medicinal Plant
BXGF05035	Salix alba	Salix alba	Medicinal Plant
BXGF05561	Drimia fugax	Drimia fugax	Others
BXGF05647	Betula davurica	Betula davurica	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}