Showing entry for Bromodomain-containing protein 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005390
Protein NameBromodomain-containing protein 1
Uniport IdO95696
GeneBRD1
Gene Id23774
DomainBromodomain; EPL1; PHD_2; PWWP; zf-HC5HC2H_2
Pfam PF00439   PF10513   PF00855  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0043249 erythrocyte maturation
Biological Process GO:0043966 histone H3 acetylation
Biological Process GO:0044154 histone H3-K14 acetylation
Biological Process GO:0043972 histone H3-K23 acetylation
Biological Process GO:0045648 positive regulation of erythrocyte differentiation
Biological Process GO:0051602 response to electrical stimulus
Biological Process GO:0035902 response to immobilization stress
molecular function GO:0042393 histone binding
molecular function GO:0046872 metal ion binding
cellular component GO:0005694 chromosome
cellular component GO:0030425 dendrite
cellular component GO:0036409 histone H3-K14 acetyltransferase complex
cellular component GO:0070776 MOZ/MORF histone acetyltransferase complex
cellular component GO:0016607 nuclear speck
cellular component GO:0005634 nucleus
cellular component GO:0043204 perikaryon
Reactome
Pathway Id Pathway Name
R-HSA-212436 Generic Transcription Pathway
R-HSA-3214847 HATs acetylate histones
R-HSA-3247509 Chromatin modifying enzymes
R-HSA-3700989 Transcriptional Regulation by TP53
R-HSA-4839726 Chromatin organization
R-HSA-5633007 Regulation of TP53 Activity
R-HSA-6804758 Regulation of TP53 Activity through Acetylation
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005890 BXGD000345 Body Height
C0006012 BXGD000360 Borderline Personality Disorder Mental Disorders
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006287 BXGD000390 Bronchopulmonary Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009178 BXGD000589 Cocaine withdrawal Chemically-Induced Disorders; Mental Disorders
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0010606 BXGD000677 Adenoid Cystic Carcinoma Neoplasms
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0022354 BXGD001540 Jaundice, Obstructive Pathological Conditions, Signs and Symptoms
C0022575 BXGD001555 Keratoconjunctivitis Sicca Eye Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0035412 BXGD002548 Rhabdomyosarcoma Neoplasms
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0200665 BXGD004045 Platelet mean volume determination (procedure)
C0220611 BXGD004295 Childhood Rhabdomyosarcoma Neoplasms
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0238644 BXGD004949 Anemia, severe Hemic and Lymphatic Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0270824 BXGD006113 Visual seizure Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0279550 BXGD006635 Adult Rhabdomyosarcoma Neoplasms
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0345967 BXGD007756 Malignant mesothelioma Neoplasms; Respiratory Tract Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0871470 BXGD011316 Systolic Pressure
C0878773 BXGD011391 Overactive Bladder Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1839839 BXGD014416 MAJOR AFFECTIVE DISORDER 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Mental Disorders
C1852197 BXGD015264 MAJOR AFFECTIVE DISORDER 1 Mental Disorders
C1970943 BXGD016852 MAJOR AFFECTIVE DISORDER 4 Mental Disorders
C1970945 BXGD016853 MAJOR AFFECTIVE DISORDER 6 Mental Disorders
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2700438 BXGD017469 MAJOR AFFECTIVE DISORDER 7 Mental Disorders
C2700439 BXGD017470 MAJOR AFFECTIVE DISORDER 8 Mental Disorders
C2700440 BXGD017471 MAJOR AFFECTIVE DISORDER 9 Mental Disorders
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0018683 5-hydroxyoxindole 149.05
BXGC0031118 N-methylpyrrolidone 99.07
BXGC0035443 L-Cysteic acid 169
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein