acompound

Showing entry for Fraxidin Methyl Ether

General Compound Information
BXGC Id	BXGC0032542
Compound Name	Fraxidin Methyl Ether
Structure
Formula	C12H12O5
InchiKey	RAYQKHLZHPFYEJ-UHFFFAOYSA-N
SMILES	COc1c(OC)c(OC)cc2c1oc(=O)cc2
Inchi	InChI=1S/C12H12O5/c1-14-8-6-7-4-5-9(13)17-10(7)12(16-3)11(8)15-2/h4-6H,1-3H3
IUPAC	6,7,8-trimethoxychromen-2-one
Molecular Weight	236.07
Pubchem Id	3083928
Chembl Id	CHEMBL253551

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

50428439

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT004601	Carbonic anhydrase 12	reviewed		CA12	18200	-	-	-
reviewed	BXGT010364	Carbonic anhydrase 7	reviewed		CA7	9280	-	-	-
reviewed	BXGT005690	Carbonic anhydrase 2	reviewed		CA2	>100000	-	-	-
reviewed	BXGT013670	Carbonic anhydrase 9	reviewed		CA9	6580	-	-	-
reviewed	BXGT018499	Carbonic anhydrase 13	reviewed		CA13	4240	-	-	-
reviewed	BXGT005689	Carbonic anhydrase 1	reviewed		CA1	9.7	-	-	-

CHEMBL

CHEMBL253551

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P00918	BXGT005690	Carbonic anhydrase 2	reviewed	-	CA2	Ki	'>'	100000	nM
P00352	BXGT005510	Retinal dehydrogenase 1	reviewed	Enzyme	ALDH1A1	Potency	'='	35481	nM
B2RXH2	BXGT002006	Lysine-specific demethylase 4E	reviewed	-	KDM4E	Potency	'='	25118	nM
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	Inhibition	'='	92	%
Q16790	BXGT013670	Carbonic anhydrase 9	reviewed	-	CA9	Ki	'='	6580	nM
O43570	BXGT004601	Carbonic anhydrase 12	reviewed	-	CA12	Ki	'='	18200	nM
Q99714	BXGT019954	3-hydroxyacyl-CoA dehydrogenase type-2	reviewed	Enzyme	HSD17B10	Potency	'='	25118	nM
Q8N1Q1	BXGT018499	Carbonic anhydrase 13	reviewed	-	CA13	Ki	'='	4240	nM
P15428	BXGT008121	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	reviewed	-	HPGD	Potency	'='	25118	nM
P43166	BXGT010364	Carbonic anhydrase 7	reviewed	-	CA7	Ki	'='	9280	nM
P00915	BXGT005689	Carbonic anhydrase 1	reviewed	-	CA1	Ki	'='	9	nM
Q9NPD5	BXGT021151	Solute carrier organic anion transporter family member 1B3	reviewed	Transporter	SLCO1B3	Inhibition	'='	92	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00890	Anthemis fuscata	Anthemis fuscata	Others
BXGF00918	Urbanodendron verrucosum	Urbanodendron verrucosum	Others
BXGF00960	Adenia fruticosa	Adenia fruticosa	Others
BXGF00967	Pteris japonica	Pteris japonica	Others
BXGF00986	Centrosema haitense	Centrosema haitense	Others
BXGF01095	Bupleurum salicifolium	Bupleurum salicifolium	Others
BXGF01128	Aster ptarmicoides	Aster ptarmicoides	Medicinal Plant
BXGF01202	Osteospermum hyoseroides	Osteospermum hyoseroides	Others
BXGF01375	Pinus massoniana	Pinus massoniana	Medicinal Plant
BXGF01441	Hopea brevipetiolaris	Hopea brevipetiolaris	Others
BXGF01494	Sedum cepaea	Sedum cepaea	Medicinal Plant
BXGF01867	Rubus phoenicolasius	Rubus phoenicolasius	Medicinal Plant
BXGF02149	Citrullus colocynthis	Citrullus colocynthis	Medicinal Plant
BXGF02244	Galium album	Galium album	Medicinal Plant
BXGF02473	Echinochloa esculenta	Echinochloa esculenta	Human Edible Plant
BXGF02746	Zanthoxylum avicennae	Zanthoxylum avicennae	Medicinal Plant
BXGF03040	Lophozia floerkei	Lophozia floerkei	Others
BXGF03254	Zanthoxylum integrifoliolum	Zanthoxylum integrifoliolum	Medicinal Plant
BXGF03561	Saussurea pulchella	Saussurea pulchella	Medicinal Plant
BXGF03800	Primula integrifolia	Primula integrifolia	Others
BXGF04107	Plagiomnium undulatum	Plagiomnium undulatum	Others
BXGF04719	Radermachera xylocarpa	Radermachera xylocarpa	Medicinal Plant
BXGF04935	Artemisia caucasica	Artemisia caucasica	Others
BXGF05122	Echinopepon bigelovii	Echinopepon bigelovii	Others
BXGF05206	Corydalis gigantea	Corydalis gigantea	Medicinal Plant
BXGF05373	Torricellia tiliifolia	Torricellia tiliifolia	Others
BXGF05697	Dysosma delavayi	Dysosma delavayi	Others
BXGF05882	Mosla japonica	Mosla japonica	Others
BXGF06132	Millettia rubiginosa	Millettia rubiginosa	Others
BXGF06152	Pittosporum illicioides	Pittosporum illicioides	Others
BXGF06232	Gomphostemma crinitum	Gomphostemma crinitum	Medicinal Plant
BXGF06267	Maharanga bicolor	Maharanga bicolor	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}