Showing entry for Carbonic anhydrase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005689
Protein NameCarbonic anhydrase 1
Uniport IdP00915
GeneCA1
Gene Id759
DomainCarb_anhydrase
Pfam PF00194  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.2 Energy metabolism hsa00910 Nitrogen metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0015701 bicarbonate transport
Biological Process GO:0035722 interleukin-12-mediated signaling pathway
Biological Process GO:0006730 one-carbon metabolic process
molecular function GO:0004064 arylesterase activity
molecular function GO:0004089 carbonate dehydratase activity
molecular function GO:0016836 hydro-lyase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
Reactome
Pathway Id Pathway Name
R-HSA-1237044 Erythrocytes take up carbon dioxide and release oxygen
R-HSA-1247673 Erythrocytes take up oxygen and release carbon dioxide
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1430728 Metabolism
R-HSA-1475029 Reversible hydration of carbon dioxide
R-HSA-1480926 O2/CO2 exchange in erythrocytes
R-HSA-168256 Immune System
R-HSA-382551 Transport of small molecules
R-HSA-447115 Interleukin-12 family signaling
R-HSA-449147 Signaling by Interleukins
R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
R-HSA-9020591 Interleukin-12 signaling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001126 BXGD000025 Renal tubular acidosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0001206 BXGD000033 Acromegaly Musculoskeletal Diseases; Nervous System Diseases; Endocrine System Diseases
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001430 BXGD000054 Adenoma Neoplasms
C0002874 BXGD000134 Aplastic Anemia Hemic and Lymphatic Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004681 BXGD000286 Bagassosis Respiratory Tract Diseases; Occupational Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011884 BXGD000762 Diabetic Retinopathy Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0017168 BXGD001101 Gastroesophageal reflux disease Digestive System Diseases
C0018834 BXGD001238 Heartburn Pathological Conditions, Signs and Symptoms
C0019099 BXGD001282 Hemorrhagic Fever, Crimean Infections
C0020550 BXGD001429 Hyperthyroidism Endocrine System Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028259 BXGD002073 Nodule
C0032273 BXGD002343 Pneumoconiosis Respiratory Tract Diseases; Occupational Diseases
C0033375 BXGD002405 Prolactinoma Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0036323 BXGD002595 Schistosomiasis Infections
C0037317 BXGD002689 Sleep disturbances Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0038013 BXGD002725 Ankylosing spondylitis Musculoskeletal Diseases
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0155550 BXGD003800 Neural hearing loss Otorhinolaryngologic Diseases
C0162316 BXGD003936 Iron deficiency anemia Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0205641 BXGD004093 Adenocarcinoma, Basal Cell Neoplasms
C0205642 BXGD004094 Adenocarcinoma, Oxyphilic Neoplasms
C0205643 BXGD004095 Carcinoma, Cribriform Neoplasms
C0205644 BXGD004096 Carcinoma, Granular Cell Neoplasms
C0205645 BXGD004097 Adenocarcinoma, Tubular Neoplasms
C0206161 BXGD004167 Reticulocyte count (procedure)
C0220650 BXGD004310 Metastatic malignant neoplasm to brain Pathological Conditions, Signs and Symptoms; Neoplasms; Nervous System Diseases
C0267055 BXGD005729 Erosive esophagitis Digestive System Diseases
C0275518 BXGD006375 Acute infectious disease Pathological Conditions, Signs and Symptoms; Infections
C0275544 BXGD006377 Congenital infectious disease Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Infections
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0334037 BXGD006980 Intestinal metaplasia
C0340044 BXGD007300 Acute exacerbation of chronic obstructive airways disease Respiratory Tract Diseases
C0456042 BXGD008861 Transient neonatal renal tubular acidosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0851578 BXGD010925 Sleep Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0947785 BXGD011495 [D]Sleep disturbances (& [hypersomnia] or [insomnia])
C1318315 BXGD012393 Serum zinc measurement
C1527336 BXGD013271 Sjogren's Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C1708349 BXGD013597 Hereditary Diffuse Gastric Cancer Digestive System Diseases; Neoplasms
C2242528 BXGD016976 Non-erosive reflux disease
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3714948 BXGD019440 PACHYONYCHIA CONGENITA 3
C4015931 BXGD020246 CARBONIC ANHYDRASE I, GUAM
C4015932 BXGD020247 CARBONIC ANHYDRASE I DEFICIENCY
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4552766 BXGD023523 Miscarriage Female Urogenital Diseases and Pregnancy Complications
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000057 3,4-Dimethoxybenzoic acid 182.17
BXGC0000077 p-Coumaric acid ethyl ester 192.21
BXGC0000203 Piperine 285.34
BXGC0000251 Syringic acid 198.17
BXGC0000279 L-Alanine 89.09
BXGC0000286 L-DOPA 197.19
BXGC0000314 Isorhamnetin 316.26
BXGC0000340 Kaempferol 286.24
BXGC0000363 Galangin 270.24
BXGC0000368 Gallic acid 170.12
BXGC0000383 (S)-Naringenin 272.25
BXGC0000436 Glycerol 92.09
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0000458 L-Asparagine 132.12
BXGC0000500 2,4-Dihydroxybenzoic acid 154.12
BXGC0000502 Gentisic acid 154.12
BXGC0000503 2,6-Dihydroxybenzoic acid 154.12
BXGC0000505 Protocatechuic acid 154.12
BXGC0000506 3,5-Dihydroxybenzoic acid 154.12
BXGC0000511 1,4-Dimethoxybenzene 138.16
BXGC0000528 Salicylic acid 138.12
BXGC0000530 Hydroquinone 110.11
BXGC0000536 Phenol 94.11
BXGC0000537 Acetylsalicylic acid 180.16
BXGC0000578 Herniarin 176.17
BXGC0000681 Umbelliferone 162.14
BXGC0001002 1,2-Benzenediol 110.11
BXGC0001502 Caffeine 194.19
BXGC0001623 L-Tryptophan 204.23
BXGC0001767 (E)-Resveratrol 228.25
BXGC0001789 Silibinin 482.44
BXGC0001857 Caffeic acid 180.16
BXGC0001868 Catechin 290.27
BXGC0001886 trans-o-Coumaric acid 164.16
BXGC0001889 p-Coumaric acid 164.16
BXGC0001899 Daidzein 254.24
BXGC0001962 Hesperetin 302.28
BXGC0002018 Morin 302.24
BXGC0002052 Aesculetin 178.14
BXGC0002071 Apigenin 270.24
BXGC0002390 Spermine 202.34
BXGC0002409 2-Ethylhexanoic acid 144.21
BXGC0002677 Sulfur 32.07
BXGC0002690 alpha-Catechin 290.27
BXGC0002698 Fluorine 19
BXGC0002722 Nitrate 62
BXGC0002978 1,2,4-Trihydroxybenzene 126.11
BXGC0003214 L-(-)-Phenylalanine 165.19
BXGC0003221 Xanthyletin 228.24
BXGC0003281 Isoscopoletin 192.17
BXGC0003533 Carbonate 60.01
BXGC0003705 Chloride 35.45
BXGC0003707 Estrogen 268.36
BXGC0003751 Cyanide 26.02
BXGC0003776 Flavones 222.24
BXGC0003951 Kaempferol 3-(p-coumaroyl-glucoside) 594.52
BXGC0004139 Sperminidine 145.25
BXGC0004358 Thiamine 265.36
BXGC0004378 3-Hydroxyflavone 238.24
BXGC0004556 1,2,3-Benzenetriol 126.11
BXGC0004559 1,3-Benzenediol 110.11
BXGC0004654 1,2-Dimethoxybenzene 138.16
BXGC0004662 2,6-Dimethylphenol 122.16
BXGC0004663 3,4-Dimethylphenol 122.16
BXGC0004666 Anisic acid 152.15
BXGC0004681 Hydrogen sulfide (H2S) 34.08
BXGC0004710 3-Hydroxybenzoic acid 138.12
BXGC0004711 4-Hydroxybenzoic acid 138.12
BXGC0004712 Methylparaben 152.15
BXGC0004713 Ethylparaben 166.17
BXGC0004730 4-Hydroxyphenylacetic acid 152.15
BXGC0004766 Methyl 4-methoxybenzoate 166.17
BXGC0004907 p-Hydroxyphenethyl trans-ferulate 314.33
BXGC0005668 2-Methoxyphenol 124.14
BXGC0005683 Quercetin 302.24
BXGC0005702 2H-1-Benzopyran-2-one 146.15
BXGC0005750 2,6-Di-tert-butyl-4-methylphenol 220.35
BXGC0005764 4-Methyl-gamma-butyrolactone 100.12
BXGC0005852 Xanthoxyletin 258.27
BXGC0005867 Serotonin 176.22
BXGC0005871 Dopamine 153.18
BXGC0005919 Biochanin A 284.27
BXGC0006162 L-Glutamic acid 147.13
BXGC0006186 L-Aspartic acid 133.1
BXGC0006193 Ellagic acid 302.19
BXGC0006195 Fraxidin 222.19
BXGC0006284 2-(4-Hydroxyphenyl)ethanol 138.16
BXGC0006291 Scopoletin 192.17
BXGC0006366 trans-Ferulic acid 194.18
BXGC0006635 Luteolin 286.24
BXGC0007046 Thiocyanic acid 59.09
BXGC0007519 Hydrocyanic acid 27.03
BXGC0008094 Potassium nitrate (KNO3) 101.1
BXGC0008101 Sodium nitrite 69
BXGC0008167 Chrysin 254.24
BXGC0008753 Isoquercitrin 464.38
BXGC0008824 Astragalin 448.38
BXGC0008958 Naringenin fructoside 272.26
BXGC0012243 Ukonan D 151.16
BXGC0012340 L-glutamine 146.14
BXGC0013237 Tyrosine 181.07
BXGC0013582 Curcumin 368.13
BXGC0013854 Histamine 111.08
BXGC0014031 Isosorbide Mononitrate 191.04
BXGC0015497 D-phenylalanine 165.08
BXGC0015574 5,7,8-Trimethoxycoumarin 236.07
BXGC0015760 Puerarin 416.11
BXGC0016154 Quercetin-3-O-Rhamnoside 448.1
BXGC0017965 4-Hydroxycoumarins 162.03
BXGC0018442 Lithospermic Acid 538.11
BXGC0018779 5,10-Dimethoxy-2,2-Dimethylpyrano[3,2-G]Chromen-8-One 288.1
BXGC0018909 Furan-2(5H)-One 84.02
BXGC0019091 D-Tryptophan 204.09
BXGC0019096 Butyrates 87.04
BXGC0019117 Tannic Acid 1700.17
BXGC0019159 4-Prop-2-Enoxychromen-2-One 202.06
BXGC0020412 Methyl Protocatechuate 168.04
BXGC0020661 Endiandrin A 328.17
BXGC0021053 6-Hydroxycoumarin 162.03
BXGC0021234 Quinazolinone 146.05
BXGC0022777 Murralongin 258.09
BXGC0023605 2-Methyl-1,1-Dioxo-1,2-Benzothiazol-3-One 197.01
BXGC0023718 D-Histidine 155.07
BXGC0024090 Sodium;4-Hydroxybenzoate 137.02
BXGC0024667 D-Tyrosine 181.07
BXGC0024810 curcumin 368.13
BXGC0027112 Benzyl (E)-P-Coumarate 254.09
BXGC0028113 Fraxine 370.09
BXGC0028840 Kaempferol-3-O-(2'',6''-Di-E-P-Coumaroyl)-Beta-Glucopyranoside 740.17
BXGC0029783 Benzoylenurea 162.04
BXGC0029784 Fumaric Acid 116.01
BXGC0030123 Ethyl 3,4-Dihydroxybenzoate 182.06
BXGC0030928 Avicennol 342.15
BXGC0031103 4,6-Dimethylpyran-2-One 124.05
BXGC0031384 Epinephrine 183.09
BXGC0031608 Histidine 155.07
BXGC0031718 propionate 73.03
BXGC0032021 (+)-Calanolide B 370.18
BXGC0032282 (-)-Dihydroguaiareticacid 330.18
BXGC0032542 Fraxidin Methyl Ether 236.07
BXGC0033329 isobutyl acetate 115.08
BXGC0033389 Zinc;1-Oxidopyridine-2-Thione 126
BXGC0033645 Sodium 2-Methylhexanoate 129.09
BXGC0033781 Methyl P-Hydroxycinnamate 178.06
BXGC0034208 3-Aminophenol 109.05
BXGC0035476 3-Hydroxycoumarin 162.03
BXGC0035699 3,4,4'-Tri-O-methylellagic acid 344.05
BXGC0036476 D-Glutamate 147.05
BXGC0036732 5-[2-(4-Hydroxyphenyl)Ethenyl]Benzene-1,3-Diol 228.08
BXGC0037637 Pentanoate 101.06
BXGC0038107 Isobutyrate 87.04
BXGC0038724 Benzyl Ferulate 284.1
BXGC0038768 2,6-Ditert-Butylphenol 206.17
BXGC0038903 Alloxanthoxyletin 258.09
BXGC0039476 Eriodictyol 288.06
BXGC0040031 4-hydroxybenzoic acid 137.02
BXGC0040462 Aminosalicylic Acid 153.04
BXGC0041110 Pentane-1,5-Diamine 102.12
BXGC0042204 Sodium Benzoate 121.03
BXGC0042510 Fluoxetine 309.13
BXGC0043125 Taxifolin 304.06
BXGC0043374 Salvianolic Acid A 494.12
BXGC0043451 Endiandrin B 328.17
BXGC0045252 Sc-560 352.06
BXGC0046948 5-Methoxy-2,2-Dimethyl-6-[(1E)-3-Methylbuta-1,3-Dienyl]Pyrano[2,3-H]Chromen-8-One 324.14
BXGC0046957 4-nitrobenzoate 166.01
BXGC0047169 Hymecromone 176.05
BXGC0047871 7-Hydroxyflavone 238.06
BXGC0048095 4-anisic acid 151.04
BXGC0048244 1H-Quinolin-2-One 145.05
BXGC0048389 Catechin 290.08
BXGC0049447 acetate 59.01
BXGC0049449 2,6-Dimethoxybenzoic Acid 182.06
BXGC0049633 4-Aminophenol 109.05
BXGC0051398 Indole 117.06
BXGC0052888 Kaempferol-3-O-(3'',4\\"-Diacetyl-2\\",6\\"-Di-E-P-Coumaroyl)-Glucoside 824.2
BXGC0052890 7-Hydroxy-8-Methoxychromen-2-One 192.04
BXGC0053235 Fraxetin 208.04
BXGC0053251 Methyl 2,4-Dihydroxybenzoate 168.04
BXGC0053401 Scopolin 354.1
BXGC0053602 Salvianolic acid B 720.17
BXGC0053883 Oxan-2-One 100.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein