Showing entry for D-Mannose


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0038164
Compound NameD-Mannose
Structure
FormulaC6H12O6
InchiKeyWQZGKKKJIJFFOK-QTVWNMPRSA-N
SMILESOC[C@H]1OC(O)[C@H]([C@H]([C@@H]1O)O)O
InchiInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1
IUPAC(3S,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
Molecular Weight180.06
Pubchem Id18950
Chembl IdCHEMBL469448
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50448403
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT021140 CD209 antigen reviewed Receptor CD209 13100000 - - -
CHEMBL CHEMBL469448
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P21139 BXGT008624 Alpha-mannosidase 2C1 reviewed - Man2c1 IC50 '~' 20000000 nM
P10323 BXGT007557 Acrosin reviewed Enzyme ACR Inhibition '=' 60 %
P10323 BXGT007557 Acrosin reviewed Enzyme ACR Inhibition '=' 48 %
Q8KHJ3 BXGT018422 Alpha 1,4 galactosyltransferase unreviewed - lgtC Kcat/Km '=' 0 /mM/min
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 13371 nM
P53624 BXGT011006 Mannosyl-oligosaccharide alpha-1,2-mannosidase IA reviewed - alpha-Man-Ia Inhibition '<' 10 %
P35247 BXGT009804 Pulmonary surfactant-associated protein D reviewed Surfactant SFTPD Inhibition '>' 90 %
P08191 BXGT006743 Type 1 fimbrin D-mannose specific adhesin reviewed - fimH IC50 '=' 560000 nM
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 100000 nM
P08191 BXGT006743 Type 1 fimbrin D-mannose specific adhesin reviewed - fimH Kd '=' 2300 nM
Q9H2X3 BXGT020457 C-type lectin domain family 4 member M reviewed Receptor CLEC4M Inhibition '>' 90 %
P11308 BXGT007684 Transcriptional regulator ERG reviewed Transcription factor ERG Potency - 50118 nM
Q9NNX6 BXGT021140 CD209 antigen reviewed Receptor CD209 Ki '=' 13100000 nM
B4EH87 BXGT002117 Lectin unreviewed - BCAM0186 IC50 '=' 10800 nM
Q6EIG7 BXGT016267 C-type lectin domain family 6 member A reviewed Receptor CLEC6A Inhibition '>' 90 %
Q9UJ71 BXGT021725 C-type lectin domain family 4 member K reviewed Receptor CD207 Inhibition '>' 90 %
P22897 BXGT008816 Macrophage mannose receptor 1 reviewed - MRC1 Inhibition '>' 90 %
P11226 BXGT007675 Mannose-binding protein C reviewed Receptor MBL2 Inhibition '>' 90 %
Q8WTT0 BXGT018987 C-type lectin domain family 4 member C reviewed Receptor CLEC4C Inhibition '>' 90 %
Q9NNX6 BXGT021140 CD209 antigen reviewed Receptor CD209 Inhibition '>' 90 %
B4EH87 BXGT002117 Lectin unreviewed - BCAM0186 Kd '=' 5150 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00181 Dandelion Taraxacum officinale Herbs and Spices
BXGF00979 Cistanche deserticola Cistanche deserticola Medicinal Plant
BXGF01668 Taraxacum platycarpum Taraxacum platycarpum Medicinal Plant
BXGF02152 Taraxacum borealisinense Taraxacum borealisinense Others
BXGF03630 Taraxacum coreanum Taraxacum coreanum Others
BXGF04310 Taraxacum mongolicum Taraxacum mongolicum Medicinal Plant
BXGF04820 Panax ginseng Panax ginseng 0
BXGF05289 Allium macrostemon Allium macrostemon Medicinal Plant
BXGF05936 Commelina communis Commelina communis Medicinal Plant
BXGF06004 Allium chinense Allium chinense Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease