protein

Showing entry for C-type lectin domain family 6 member A

General Target Information
BXGT Id	BXGT016267
Protein Name	C-type lectin domain family 6 member A
Uniport Id	Q6EIG7
Gene	CLEC6A
Gene Id	93978
Domain	Lectin_C
Pfam	PF00059
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name
5. Organismal Systems	5.1 Immune system	hsa04625	C-type lectin receptor signaling pathway

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0002250	adaptive immune response
Biological Process	GO:0050832	defense response to fungus
Biological Process	GO:0045087	innate immune response
Biological Process	GO:0050715	positive regulation of cytokine secretion
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process	GO:0002223	stimulatory C-type lectin receptor signaling pathway
molecular function	GO:0005509	calcium ion binding
molecular function	GO:0030246	carbohydrate binding
molecular function	GO:0005537	mannose binding
cellular component	GO:0016021	integral component of membrane
cellular component	GO:0005886	plasma membrane

Reactome

Pathway Id	Pathway Name
R-HSA-168249	Innate Immune System
R-HSA-168249	Innate Immune System
R-HSA-168256	Immune System
R-HSA-168256	Immune System
R-HSA-5621480	Dectin-2 family
R-HSA-5621480	Dectin-2 family
R-HSA-5621481	C-type lectin receptors (CLRs)
R-HSA-5621481	C-type lectin receptors (CLRs)

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0003850	BXGD000225	Arteriosclerosis	Cardiovascular Diseases
C0003873	BXGD000236	Rheumatoid Arthritis	Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004153	BXGD000260	Atherosclerosis	Cardiovascular Diseases
C0006826	BXGD000408	Malignant Neoplasms	Neoplasms
C0008373	BXGD000536	Cholesteatoma	Skin and Connective Tissue Diseases
C0010414	BXGD000669	Infection by Cryptococcus neoformans	Infections
C0010674	BXGD000683	Cystic Fibrosis	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011636	BXGD000743	Dermatophytosis	Infections; Skin and Connective Tissue Diseases
C0018813	BXGD001232	Myocardial rupture	Cardiovascular Diseases
C0024116	BXGD001733	Lung Diseases, Fungal	Infections; Respiratory Tract Diseases
C0026691	BXGD001917	Mucocutaneous Lymph Node Syndrome	Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026946	BXGD001951	Mycoses	Infections
C0027051	BXGD001963	Myocardial Infarction	Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0032285	BXGD002344	Pneumonia	Infections; Respiratory Tract Diseases
C0040247	BXGD002852	Tinea	Infections; Skin and Connective Tissue Diseases
C0041296	BXGD002903	Tuberculosis	Infections
C0042384	BXGD002979	Vasculitis	Cardiovascular Diseases
C0153252	BXGD003616	Systemic candidiasis	Infections
C0153676	BXGD003679	Secondary malignant neoplasm of lung	Neoplasms; Respiratory Tract Diseases
C0276655	BXGD006439	Infection by Aspergillus fumigatus	Infections
C0276688	BXGD006445	Pulmonary cryptococcosis	Infections; Respiratory Tract Diseases
C0494165	BXGD009022	Secondary malignant neoplasm of liver	Digestive System Diseases; Neoplasms
C0876973	BXGD011322	Infectious Lung Disorder	Infections; Respiratory Tract Diseases
C0947751	BXGD011494	Vascular inflammations	Cardiovascular Diseases
C1269955	BXGD012005	Tumor Cell Invasion
C1306459	BXGD012361	Primary malignant neoplasm	Neoplasms
C1535939	BXGD013323	Pneumocystis jiroveci pneumonia	Infections; Respiratory Tract Diseases
C1998061	BXGD016867	Malassezia folliculitis	Skin and Connective Tissue Diseases
C2350529	BXGD017080	Pulmonary Aspergillosis	Infections; Respiratory Tract Diseases
C2350530	BXGD017081	Bronchopulmonary Aspergillosis	Infections; Respiratory Tract Diseases
C3266262	BXGD018600	Multiple Chronic Conditions	Pathological Conditions, Signs and Symptoms
C3714636	BXGD019421	Pneumonitis	Infections; Respiratory Tract Diseases
C3854222	BXGD019826	Human immunodeficiency virus (HIV) II infection category B1
C4324563	BXGD022772	Neutrophil extracellular trap formation
C4703473	BXGD023650	Atherosclerotic lesion	Cardiovascular Diseases

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0002586	Calcium		40.08
BXGC0018397	beta-1,4-mannan		180.06
BXGC0038164	D-Mannose		180.06
BXGC0050194	alpha-D-Mannose		180.06

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}