Showing entry for 3-Epifagomine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0038823
Compound Name3-Epifagomine
Structure
FormulaC6H13NO3
InchiKeyYZNNBIPIQWYLDM-NGJCXOISSA-N
SMILESOC[C@H]1NCC[C@@H]([C@@H]1O)O
InchiInChI=1S/C6H13NO3/c8-3-4-6(10)5(9)1-2-7-4/h4-10H,1-3H2/t4-,5+,6-/m1/s1
IUPAC(2R,3R,4S)-2-(hydroxymethyl)piperidine-3,4-diol
Molecular Weight147.09
Pubchem Id10290867
Chembl IdCHEMBL456583
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50292389
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT015223 Beta-galactosidase reviewed GLB1 - 3100 - -
reviewed BXGT015223 Beta-galactosidase reviewed GLB1 - 1500 - -
reviewed BXGT008901 Sucrase-isomaltase, intestinal reviewed Si - 6000 - -
reviewed BXGT014115 Lysosomal acid glucosylceramidase reviewed GBA - 5600 - -
reviewed BXGT015223 Beta-galactosidase reviewed GLB1 - 3000 - -
reviewed BXGT012651 Lactase-phlorizin hydrolase reviewed Lct - 4300 - -
reviewed BXGT020533 Non-lysosomal glucosylceramidase reviewed GBA2 - >1000000 - -
reviewed BXGT005280 Ceramide glucosyltransferase reviewed Ugcg - >10000 - -
reviewed BXGT012651 Lactase-phlorizin hydrolase reviewed Lct - 1900 - -
reviewed BXGT016460 Lysosomal alpha-glucosidase reviewed Gaa - 500000 - -
reviewed BXGT017923 Neutral alpha-glucosidase C reviewed Ganc - 6400 - -
reviewed BXGT007574 Beta-glucosidase A reviewed bglA - 100000 - -
reviewed BXGT006142 Tissue alpha-L-fucosidase reviewed FUCA1 - 1000000 - -
CHEMBL CHEMBL456583
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
O88693 BXGT005280 Ceramide glucosyltransferase reviewed - Ugcg Inhibition - - -
Q42656 BXGT014579 Alpha-galactosidase reviewed - Inhibition - - -
Q14697 BXGT013501 Neutral alpha-glucosidase AB reviewed Enzyme GANAB IC50 - - -
O70282 BXGT005062 Trehalase unreviewed - IC50 - - -
O88693 BXGT005280 Ceramide glucosyltransferase reviewed - Ugcg IC50 '>' 10000 nM
P23739 BXGT008901 Sucrase-isomaltase, intestinal reviewed - Si IC50 '=' 6000 nM
P04062 BXGT006140 Lysosomal acid glucosylceramidase reviewed - GBA Inhibition '<' 50 %
Q58D55 BXGT015223 Beta-galactosidase reviewed - GLB1 IC50 '=' 3000 nM
Q9HCG7 BXGT020533 Non-lysosomal glucosylceramidase reviewed - GBA2 IC50 '>' 1000000 nM
P00722 BXGT005626 Beta-galactosidase reviewed - lacZ Inhibition - - -
P23739 BXGT008901 Sucrase-isomaltase, intestinal reviewed - Si Inhibition '<' 50 %
Q58D55 BXGT015223 Beta-galactosidase reviewed - GLB1 IC50 '=' 1500 nM
D3ZUM4 BXGT002920 Beta-galactosidase unreviewed - Glb1 IC50 '=' 4000 nM
P10482 BXGT007574 Beta-glucosidase A reviewed - bglA IC50 - - -
D3ZUM4 BXGT002920 Beta-galactosidase unreviewed - Glb1 IC50 - - -
P10482 BXGT007574 Beta-glucosidase A reviewed - bglA IC50 '=' 100000 nM
Q6P7A9 BXGT016460 Lysosomal alpha-glucosidase reviewed - Gaa IC50 - - -
Q9MYM4 BXGT021111 Lysosomal alpha-glucosidase reviewed - GAA IC50 - - -
Q58D55 BXGT015223 Beta-galactosidase reviewed - GLB1 IC50 - - -
Q02401 BXGT012651 Lactase-phlorizin hydrolase reviewed - Lct IC50 '=' 4300 nM
P04066 BXGT006142 Tissue alpha-L-fucosidase reviewed - FUCA1 IC50 '=' 1000000 nM
Q02401 BXGT012651 Lactase-phlorizin hydrolase reviewed - Lct IC50 '=' 1900 nM
Q2KIM0 BXGT014117 Tissue alpha-L-fucosidase reviewed - FUCA1 Inhibition '<' 50 %
Q2KHZ8 BXGT014115 Lysosomal acid glucosylceramidase reviewed - GBA IC50 '=' 5600 nM
Q6P7A9 BXGT016460 Lysosomal alpha-glucosidase reviewed - Gaa IC50 '=' 500000 nM
Q8BVW0 BXGT017923 Neutral alpha-glucosidase C reviewed - Ganc IC50 '=' 6400 nM
Q58D55 BXGT015223 Beta-galactosidase reviewed - GLB1 IC50 '=' 3100 nM
C0HJB3 BXGT002376 Alpha-mannosidase reviewed - Inhibition - - -
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00845 Castanospermum australe Castanospermum australe Vegetables
BXGF00916 Erythrina speciosa Erythrina speciosa Others
BXGF00978 Prunus prostrata Prunus prostrata Medicinal Plant
BXGF02214 Morus bombycis Morus bombycis Medicinal Plant
BXGF02560 Richteria pyrethroides Richteria pyrethroides Others
BXGF03204 Xanthocercis zambesiaca Xanthocercis zambesiaca Others
BXGF04099 Piper divaricatum Piper divaricatum Others
BXGF04110 Helichrysum drakensbergense Helichrysum drakensbergense Others
BXGF04167 Santolina pectinata Santolina pectinata Others
BXGF04185 Prosopis africana Prosopis africana Medicinal Plant
BXGF04364 Commiphora sphaerocarpa Commiphora sphaerocarpa Others
BXGF04374 Satureja vulgaris Satureja vulgaris Others
BXGF04607 Morus alba Morus alba Medicinal Plant
BXGF05068 aglaonema treubii aglaonema treubii Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease