Showing entry for Canthin-6-One


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0039309
Compound NameCanthin-6-One
Structure
FormulaC14H8N2O
InchiKeyZERVJPYNQLONEK-UHFFFAOYSA-N
SMILESO=c1ccc2c3n1c1ccccc1c3ccn2
InchiInChI=1S/C14H8N2O/c17-13-6-5-11-14-10(7-8-15-11)9-3-1-2-4-12(9)16(13)14/h1-8H
IUPAC
Molecular Weight220.06
Pubchem Id97176
Chembl IdCHEMBL156897
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL156897
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P18031 BXGT008369 Tyrosine-protein phosphatase non-receptor type 1 reviewed - PTPN1 Inhibition '=' 15 %
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase reviewed Kinase AKT1 Inhibition - - -
P0AES4 BXGT007329 DNA gyrase subunit A reviewed - gyrA Activity '=' 13 %
P0AES6 BXGT007331 DNA gyrase subunit B reviewed - gyrB Activity '=' 13 %
Q9ES14 BXGT020314 Gamma-aminobutyric acid receptor subunit epsilon reviewed - Gabre Ki '=' 10000 nM
Q91ZM7 BXGT019327 GABA theta subunit unreviewed - Gabrq Ki '=' 10000 nM
P63138 BXGT011502 Gamma-aminobutyric acid receptor subunit beta-2 reviewed - Gabrb2 Ki '=' 10000 nM
P63079 BXGT011491 Gamma-aminobutyric acid receptor subunit beta-3 reviewed - Gabrb3 Ki '=' 10000 nM
P62813 BXGT011460 Gamma-aminobutyric acid receptor subunit alpha-1 reviewed - Gabra1 Ki '=' 10000 nM
P30191 BXGT009410 Gamma-aminobutyric acid receptor subunit alpha-6 reviewed - Gabra6 Ki '=' 10000 nM
P28473 BXGT009261 Gamma-aminobutyric acid receptor subunit gamma-3 reviewed - Gabrg3 Ki '=' 10000 nM
P28471 BXGT009259 Gamma-aminobutyric acid receptor subunit alpha-4 reviewed - Gabra4 Ki '=' 10000 nM
P23576 BXGT008885 Gamma-aminobutyric acid receptor subunit alpha-2 reviewed - Gabra2 Ki '=' 10000 nM
P23574 BXGT008884 Gamma-aminobutyric acid receptor subunit gamma-1 reviewed - Gabrg1 Ki '=' 10000 nM
P20236 BXGT008551 Gamma-aminobutyric acid receptor subunit alpha-3 reviewed - Gabra3 Ki '=' 10000 nM
P19969 BXGT008536 Gamma-aminobutyric acid receptor subunit alpha-5 reviewed - Gabra5 Ki '=' 10000 nM
P18508 BXGT008412 Gamma-aminobutyric acid receptor subunit gamma-2 reviewed - Gabrg2 Ki '=' 10000 nM
P18506 BXGT008410 Gamma-aminobutyric acid receptor subunit delta reviewed - Gabrd Ki '=' 10000 nM
P15431 BXGT008122 Gamma-aminobutyric acid receptor subunit beta-1 reviewed - Gabrb1 Ki '=' 10000 nM
O09028 BXGT004049 Gamma-aminobutyric acid receptor subunit pi reviewed - Gabrp Ki '=' 10000 nM
P0AES4 BXGT007329 DNA gyrase subunit A reviewed - gyrA Activity '=' 12 %
P0AES6 BXGT007331 DNA gyrase subunit B reviewed - gyrB Activity '=' 12 %
P0AES4 BXGT007329 DNA gyrase subunit A reviewed - gyrA Activity '=' 7 %
P0AES6 BXGT007331 DNA gyrase subunit B reviewed - gyrB Activity '=' 7 %
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00352 Japanese chestnut Castanea crenata Nuts
BXGF01003 Carpobrotus edulis Carpobrotus edulis Medicinal Plant
BXGF01056 Geigeria schinzii Geigeria schinzii Others
BXGF01062 Asplenium normale Asplenium normale Others
BXGF01137 Centrolobium tomentosum Centrolobium tomentosum Others
BXGF01201 Psilostrophe cooperi Psilostrophe cooperi Others
BXGF01287 Papaver radicatum Papaver radicatum Others
BXGF01305 Trifolium alexandrinum Trifolium alexandrinum Medicinal Plant
BXGF01420 Pinus glauca Pinus glauca Others
BXGF01496 Ophryosporus charua Ophryosporus charua Others
BXGF01507 Sideritis tragoriganum Sideritis tragoriganum Others
BXGF01514 Blainvillea latifolia Blainvillea latifolia Others
BXGF01636 Prosopis kuntzei Prosopis kuntzei Medicinal Plant
BXGF01677 Leontice kiangnanensis Leontice kiangnanensis Others
BXGF01705 Cheilanthes marantae Cheilanthes marantae Others
BXGF01778 Solanum jamaicense Solanum jamaicense Others
BXGF01808 Helichrysum angustifolium Helichrysum angustifolium Others
BXGF01868 Vitex negundo Vitex negundo Medicinal Plant
BXGF01895 Lippia carviodora Lippia carviodora Medicinal Plant
BXGF01912 Ceratophyllum submersum Ceratophyllum submersum Others
BXGF01936 Brucea javanica Brucea javanica Medicinal Plant
BXGF01971 Myrica nana Myrica nana Others
BXGF02043 Ailanthus altissima Ailanthus altissima Medicinal Plant
BXGF02061 Dracocephalum kotschyi Dracocephalum kotschyi Medicinal Plant
BXGF03068 Stenocereus thurberi Stenocereus thurberi Human Edible Plant
BXGF03254 Zanthoxylum integrifoliolum Zanthoxylum integrifoliolum Medicinal Plant
BXGF03427 Phellodendron chinense Phellodendron chinense Medicinal Plant
BXGF03828 Phellodendron amurense Phellodendron amurense Medicinal Plant
BXGF03940 Pachycereus pringlei Pachycereus pringlei Human Edible Plant
BXGF04256 Phellodendron chinese Phellodendron chinese Others
BXGF05113 Bersama swinnyi Bersama swinnyi Others
BXGF05573 Goniothalamus undulatus Goniothalamus undulatus Others
BXGF05690 Pteris spinulosa Pteris spinulosa Others
BXGF06009 Picrasma quassioides Picrasma quassioides Medicinal Plant
BXGF06066 Nemuaron humboldtii Nemuaron humboldtii Others
BXGF06099 Lophocereus marginatus Lophocereus marginatus Medicinal Plant
BXGF06117 Helichrysum sutherlandii Helichrysum sutherlandii Medicinal Plant
BXGF06134 Aralidium pinnatifidum Aralidium pinnatifidum Others
BXGF06265 Euphorbia resinifera Euphorbia resinifera Medicinal Plant
BXGF06320 Eurycoma longifolia Eurycoma longifolia Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease