Showing entry for Gamma-aminobutyric acid receptor subunit alpha-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011460
Protein NameGamma-aminobutyric acid receptor subunit alpha-1
Uniport IdP62813
GeneGabra1
Gene Id29705
DomainNeur_chan_LBD; Neur_chan_memb
Pfam PF02931   PF02932  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071420 cellular response to histamine
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:1902476 chloride transmembrane transport
Biological Process GO:0006821 chloride transport
Biological Process GO:0007214 gamma-aminobutyric acid signaling pathway
Biological Process GO:1904862 inhibitory synapse assembly
Biological Process GO:0034220 ion transmembrane transport
Biological Process GO:0050877 nervous system process
Biological Process GO:0042391 regulation of membrane potential
Biological Process GO:0060078 regulation of postsynaptic membrane potential
Biological Process GO:0007165 signal transduction
Biological Process GO:0051932 synaptic transmission, GABAergic
molecular function GO:0008503 benzodiazepine receptor activity
molecular function GO:0005254 chloride channel activity
molecular function GO:0008144 drug binding
molecular function GO:0004890 GABA-A receptor activity
molecular function GO:0022851 GABA-gated chloride ion channel activity
molecular function GO:0005237 inhibitory extracellular ligand-gated ion channel activity
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
cellular component GO:0034707 chloride channel complex
cellular component GO:0030659 cytoplasmic vesicle membrane
cellular component GO:0032590 dendrite membrane
cellular component GO:1902711 GABA-A receptor complex
cellular component GO:0098982 GABA-ergic synapse
cellular component GO:1902710 GABA receptor complex
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099060 integral component of postsynaptic specialization membrane
cellular component GO:0043005 neuron projection
cellular component GO:0005886 plasma membrane
cellular component GO:0098794 postsynapse
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000651 Harmalan 184.24
BXGC0000688 (S)-Spinacine 167.17
BXGC0000982 L-Homocysteine 135.19
BXGC0001545 Harmine 212.25
BXGC0002064 Amentoflavone 538.46
BXGC0002071 Apigenin 270.24
BXGC0002433 Dihydro-2(3H)-thiophenone 102.16
BXGC0002867 Lappaurin 284.74
BXGC0003196 Aripiprazole 448.39
BXGC0003343 Guanidino acetic acid 117.11
BXGC0003776 Flavones 222.24
BXGC0003963 Dechlorodiazepam 250.3
BXGC0004115 Norharman 168.19
BXGC0004665 4-Aminobutyric acid 103.12
BXGC0004673 Caprolactam 113.16
BXGC0005683 Quercetin 302.24
BXGC0005874 Racemethionine 149.21
BXGC0006108 1H-Imidazole-4(5)-acetic acid 126.11
BXGC0006183 L-Cystine 240.3
BXGC0006970 2-Methyl-gamma-butyrolactone 100.12
BXGC0007014 Harman 182.22
BXGC0007091 2-Acetylpyridine 121.14
BXGC0008167 Chrysin 254.24
BXGC0013448 (9Z)-9-Heptadecene-4,6-diyne-1-ol 246.2
BXGC0013799 Heptadeca-8,10-Diene-4,6-Diyne-1,12-Diol 260.18
BXGC0014991 Ethyl Beta-Carboline-3-Carboxylate 240.09
BXGC0018317 isoquinoline 129.06
BXGC0018397 beta-1,4-mannan 180.06
BXGC0018619 2-pyrrolidone 85.05
BXGC0019303 2-piperidone 99.07
BXGC0019461 Heptadec-9-Ene-4,6-Diyne-1,8-Diol 262.19
BXGC0022192 Bufotenine 204.13
BXGC0024591 Oleamide 281.27
BXGC0025887 5-Hydroxyflavone 238.06
BXGC0026579 4-Ureido-butyric acid 146.07
BXGC0030085 Bicuculline 367.11
BXGC0033089 Falcarindiol 260.18
BXGC0034128 Heptadec-8-Ene-4,6-Diyne-1,10-Diol 262.19
BXGC0036977 2,3-Dihydroenanthetol 244.18
BXGC0038001 17-Hydroxy-Heptadeca-7,9-Diene-11,13-Diyn-4-One 258.16
BXGC0038837 Pseudohypericin 520.08
BXGC0039026 Cicutoxin 258.16
BXGC0039309 Canthin-6-One 220.06
BXGC0040234 17-Hydroxyheptadeca-5,7,9-Trien-11,13-Diyn-4-One 256.15
BXGC0042101 picolinaldehyde 107.04
BXGC0042462 Cysteine 121.02
BXGC0042531 (Cis)-Heptadeca-8,10,12-Triene-4,6-Diyne-1,14-Diol 258.16
BXGC0042596 Isoniazid 137.06
BXGC0044598 Guvacine 127.06
BXGC0045250 Nicotinaldehyde 107.04
BXGC0045489 [(8E,10E,12E,14R)-14-Hydroxyheptadeca-8,10,12-Trien-4,6-Diynyl] Acetate 300.17
BXGC0047871 7-Hydroxyflavone 238.06
BXGC0050172 N,N-Dimethyltryptamine 188.13
BXGC0050194 alpha-D-Mannose 180.06
BXGC0051995 Wedelolactone 314.04
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein