Showing entry for Gamma-aminobutyric acid receptor subunit beta-3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011491
Protein NameGamma-aminobutyric acid receptor subunit beta-3
Uniport IdP63079
GeneGabrb3
Gene Id24922
DomainNeur_chan_LBD; Neur_chan_memb
Pfam PF02931   PF02932  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071420 cellular response to histamine
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:1902476 chloride transmembrane transport
Biological Process GO:0090102 cochlea development
Biological Process GO:0007214 gamma-aminobutyric acid signaling pathway
Biological Process GO:0060080 inhibitory postsynaptic potential
Biological Process GO:1904862 inhibitory synapse assembly
Biological Process GO:0060119 inner ear receptor cell development
Biological Process GO:0060384 innervation
Biological Process GO:0034220 ion transmembrane transport
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:1901215 negative regulation of neuron death
Biological Process GO:0050877 nervous system process
Biological Process GO:0048666 neuron development
Biological Process GO:0042391 regulation of membrane potential
Biological Process GO:0043523 regulation of neuron apoptotic process
Biological Process GO:0060021 roof of mouth development
Biological Process GO:0007605 sensory perception of sound
Biological Process GO:0007165 signal transduction
Biological Process GO:0051932 synaptic transmission, GABAergic
molecular function GO:0035612 AP-2 adaptor complex binding
molecular function GO:0005254 chloride channel activity
molecular function GO:0004890 GABA-A receptor activity
molecular function GO:0022851 GABA-gated chloride ion channel activity
molecular function GO:0042802 identical protein binding
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
cellular component GO:0034707 chloride channel complex
cellular component GO:0030659 cytoplasmic vesicle membrane
cellular component GO:1902711 GABA-A receptor complex
cellular component GO:0098982 GABA-ergic synapse
cellular component GO:0060077 inhibitory synapse
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099055 integral component of postsynaptic membrane
cellular component GO:0099060 integral component of postsynaptic specialization membrane
cellular component GO:0043005 neuron projection
cellular component GO:0005886 plasma membrane
cellular component GO:0045202 synapse
cellular component GO:0043195 terminal bouton
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000651 Harmalan 184.24
BXGC0000688 (S)-Spinacine 167.17
BXGC0001545 Harmine 212.25
BXGC0002064 Amentoflavone 538.46
BXGC0002071 Apigenin 270.24
BXGC0002433 Dihydro-2(3H)-thiophenone 102.16
BXGC0002867 Lappaurin 284.74
BXGC0003343 Guanidino acetic acid 117.11
BXGC0003776 Flavones 222.24
BXGC0003963 Dechlorodiazepam 250.3
BXGC0004115 Norharman 168.19
BXGC0004665 4-Aminobutyric acid 103.12
BXGC0004673 Caprolactam 113.16
BXGC0006108 1H-Imidazole-4(5)-acetic acid 126.11
BXGC0006970 2-Methyl-gamma-butyrolactone 100.12
BXGC0007014 Harman 182.22
BXGC0007091 2-Acetylpyridine 121.14
BXGC0008167 Chrysin 254.24
BXGC0013448 (9Z)-9-Heptadecene-4,6-diyne-1-ol 246.2
BXGC0013799 Heptadeca-8,10-Diene-4,6-Diyne-1,12-Diol 260.18
BXGC0018317 isoquinoline 129.06
BXGC0018619 2-pyrrolidone 85.05
BXGC0019303 2-piperidone 99.07
BXGC0019461 Heptadec-9-Ene-4,6-Diyne-1,8-Diol 262.19
BXGC0022192 Bufotenine 204.13
BXGC0024591 Oleamide 281.27
BXGC0025887 5-Hydroxyflavone 238.06
BXGC0026579 4-Ureido-butyric acid 146.07
BXGC0030085 Bicuculline 367.11
BXGC0033089 Falcarindiol 260.18
BXGC0034128 Heptadec-8-Ene-4,6-Diyne-1,10-Diol 262.19
BXGC0036977 2,3-Dihydroenanthetol 244.18
BXGC0038001 17-Hydroxy-Heptadeca-7,9-Diene-11,13-Diyn-4-One 258.16
BXGC0039026 Cicutoxin 258.16
BXGC0039309 Canthin-6-One 220.06
BXGC0040234 17-Hydroxyheptadeca-5,7,9-Trien-11,13-Diyn-4-One 256.15
BXGC0042101 picolinaldehyde 107.04
BXGC0042531 (Cis)-Heptadeca-8,10,12-Triene-4,6-Diyne-1,14-Diol 258.16
BXGC0042596 Isoniazid 137.06
BXGC0044598 Guvacine 127.06
BXGC0045250 Nicotinaldehyde 107.04
BXGC0045489 [(8E,10E,12E,14R)-14-Hydroxyheptadeca-8,10,12-Trien-4,6-Diynyl] Acetate 300.17
BXGC0047871 7-Hydroxyflavone 238.06
BXGC0050172 N,N-Dimethyltryptamine 188.13
BXGC0051995 Wedelolactone 314.04
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein