acompound

Showing entry for 5,6,7,3',4',5'-Hexamethoxyflavone

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0040560
Compound Name	5,6,7,3',4',5'-Hexamethoxyflavone
Structure
Formula	C21H22O8
InchiKey	DYDFNKUHYXHWFM-UHFFFAOYSA-N
SMILES	COc1c(OC)cc(cc1OC)c1cc(=O)c2c(o1)cc(c(c2OC)OC)OC
Inchi	InChI=1S/C21H22O8/c1-23-15-7-11(8-16(24-2)19(15)26-4)13-9-12(22)18-14(29-13)10-17(25-3)20(27-5)21(18)28-6/h7-10H,1-6H3
IUPAC	5,6,7-trimethoxy-2-(3,4,5-trimethoxyphenyl)chromen-4-one
Molecular Weight	402.13
Pubchem Id	185670
Chembl Id	CHEMBL370963

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	900	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P49185	BXGT010682	Mitogen-activated protein kinase 8	reviewed	-	Mapk8	Activity	-	-	-
Q07014	BXGT012913	Tyrosine-protein kinase Lyn	reviewed	-	Lyn	Activity	-	-	-
P21708	BXGT008684	Mitogen-activated protein kinase 3	reviewed	-	Mapk3	Activity	-	-	-
P63086	BXGT011494	Mitogen-activated protein kinase 1	reviewed	-	Mapk1	Activity	-	-	-
Q64725	BXGT016130	Tyrosine-protein kinase SYK	reviewed	-	Syk	Activity	-	-	-
P10686	BXGT007601	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	reviewed	-	Plcg1	Activity	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	900	nM
Q15118	BXGT013540	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	reviewed	Kinase	PDK1	Inhibition	'='	16	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF03614	Ageratum conyzoides	Ageratum conyzoides	Medicinal Plant
BXGF04382	Murraya paniculata	Murraya paniculata	Medicinal Plant
BXGF05000	Citrus reticulate	Citrus reticulate	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}