Showing entry for Mitogen-activated protein kinase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011494
Protein NameMitogen-activated protein kinase 1
Uniport IdP63086
GeneMapk1
Gene Id116590
DomainPkinase
Pfam PF00069  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007568 aging
Biological Process GO:0009887 animal organ morphogenesis
Biological Process GO:0006915 apoptotic process
Biological Process GO:0050853 B cell receptor signaling pathway
Biological Process GO:0060020 Bergmann glial cell differentiation
Biological Process GO:0061308 cardiac neural crest cell development involved in heart development
Biological Process GO:0072584 caveolin-mediated endocytosis
Biological Process GO:0007049 cell cycle
Biological Process GO:0007166 cell surface receptor signaling pathway
Biological Process GO:0034198 cellular response to amino acid starvation
Biological Process GO:0071276 cellular response to cadmium ion
Biological Process GO:0006974 cellular response to DNA damage stimulus
Biological Process GO:1903351 cellular response to dopamine
Biological Process GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus
Biological Process GO:0071310 cellular response to organic substance
Biological Process GO:0034614 cellular response to reactive oxygen species
Biological Process GO:0071356 cellular response to tumor necrosis factor
Biological Process GO:0019858 cytosine metabolic process
Biological Process GO:0046697 decidualization
Biological Process GO:0015966 diadenosine tetraphosphate biosynthetic process
Biological Process GO:0038127 ERBB signaling pathway
Biological Process GO:0070371 ERK1 and ERK2 cascade
Biological Process GO:0060324 face development
Biological Process GO:0007507 heart development
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0060716 labyrinthine layer blood vessel development
Biological Process GO:0031663 lipopolysaccharide-mediated signaling pathway
Biological Process GO:0060291 long-term synaptic potentiation
Biological Process GO:0060425 lung morphogenesis
Biological Process GO:0033598 mammary gland epithelial cell proliferation
Biological Process GO:0000165 MAPK cascade
Biological Process GO:0045596 negative regulation of cell differentiation
Biological Process GO:0014032 neural crest cell development
Biological Process GO:0042473 outer ear morphogenesis
Biological Process GO:0018105 peptidyl-serine phosphorylation
Biological Process GO:0018107 peptidyl-threonine phosphorylation
Biological Process GO:0060045 positive regulation of cardiac muscle cell proliferation
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0010759 positive regulation of macrophage chemotaxis
Biological Process GO:0120041 positive regulation of macrophage proliferation
Biological Process GO:0010800 positive regulation of peptidyl-threonine phosphorylation
Biological Process GO:0042307 positive regulation of protein import into nucleus
Biological Process GO:0051973 positive regulation of telomerase activity
Biological Process GO:1904355 positive regulation of telomere capping
Biological Process GO:0032212 positive regulation of telomere maintenance via telomerase
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045727 positive regulation of translation
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0030641 regulation of cellular pH
Biological Process GO:0051493 regulation of cytoskeleton organization
Biological Process GO:2000641 regulation of early endosome to late endosome transport
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0090170 regulation of Golgi inheritance
Biological Process GO:0030278 regulation of ossification
Biological Process GO:0031647 regulation of protein stability
Biological Process GO:0032872 regulation of stress-activated MAPK cascade
Biological Process GO:0070849 response to epidermal growth factor
Biological Process GO:0043627 response to estrogen
Biological Process GO:0043330 response to exogenous dsRNA
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0035094 response to nicotine
Biological Process GO:0009636 response to toxic substance
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0007165 signal transduction
Biological Process GO:0051403 stress-activated MAPK cascade
Biological Process GO:0050852 T cell receptor signaling pathway
Biological Process GO:0048538 thymus development
Biological Process GO:0030878 thyroid gland development
Biological Process GO:0060440 trachea formation
molecular function GO:0005524 ATP binding
molecular function GO:0003690 double-stranded DNA binding
molecular function GO:0042802 identical protein binding
molecular function GO:0016301 kinase activity
molecular function GO:0004707 MAP kinase activity
molecular function GO:0004708 MAP kinase kinase activity
molecular function GO:0031435 mitogen-activated protein kinase kinase kinase binding
molecular function GO:0019902 phosphatase binding
molecular function GO:0001784 phosphotyrosine residue binding
molecular function GO:0004672 protein kinase activity
molecular function GO:0019901 protein kinase binding
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity
molecular function GO:0008134 transcription factor binding
cellular component GO:0030424 axon
cellular component GO:0005901 caveola
cellular component GO:0005737 cytoplasm
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0032839 dendrite cytoplasm
cellular component GO:0005769 early endosome
cellular component GO:0005925 focal adhesion
cellular component GO:0005794 Golgi apparatus
cellular component GO:0005770 late endosome
cellular component GO:0005815 microtubule organizing center
cellular component GO:0005739 mitochondrion
cellular component GO:0072686 mitotic spindle
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0043204 perikaryon
cellular component GO:0005886 plasma membrane
cellular component GO:0032991 protein-containing complex
cellular component GO:0031143 pseudopodium
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0001545 Harmine 212.25
BXGC0002588 Magnesium 24.31
BXGC0002906 Caffeic acid ester 284.31
BXGC0007052 Olomoucine 298.34
BXGC0008973 6-Hydroxyluteolin 6,7,3',4'-tetramethyl ether 358.34
BXGC0015759 5,6,8,3',6'-Pentamethoxy Flavone 372.12
BXGC0030612 tetraethylene glycol 194.12
BXGC0030998 5-[(2R,3S,4R,5R)-5-(1,3-Benzodioxol-5-Yl)-3,4-Dimethyloxolan-2-Yl]-1,3-Benzodioxole 340.13
BXGC0036201 D-Epigalbacin 340.13
BXGC0040560 5,6,7,3',4',5'-Hexamethoxyflavone 402.13
BXGC0046996 Thioguanine 167.03
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein