Showing entry for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1



                       
General Target Information
BXGT IdBXGT007601
Protein Name1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Uniport IdP10686
GenePlcg1
Gene Id25738
DomainC2; PI-PLC-X; PI-PLC-Y; SH2; SH3_1
Pfam PF00168   PF00388   PF00387   PF00017   PF00018  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0019722 calcium-mediated signaling
Biological Process GO:0016477 cell migration
Biological Process GO:0071364 cellular response to epidermal growth factor stimulus
Biological Process GO:0007173 epidermal growth factor receptor signaling pathway
Biological Process GO:0032959 inositol trisphosphate biosynthetic process
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0050804 modulation of chemical synaptic transmission
Biological Process GO:0009395 phospholipid catabolic process
Biological Process GO:0045766 positive regulation of angiogenesis
Biological Process GO:0043536 positive regulation of blood vessel endothelial cell migration
Biological Process GO:2000353 positive regulation of endothelial cell apoptotic process
Biological Process GO:0010634 positive regulation of epithelial cell migration
Biological Process GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
Biological Process GO:1905564 positive regulation of vascular endothelial cell proliferation
Biological Process GO:0009306 protein secretion
Biological Process GO:1901339 regulation of store-operated calcium channel activity
Biological Process GO:0009629 response to gravity
Biological Process GO:0042542 response to hydrogen peroxide
Biological Process GO:0043278 response to morphine
Biological Process GO:0010243 response to organonitrogen compound
Biological Process GO:0007165 signal transduction
Biological Process GO:0050852 T cell receptor signaling pathway
molecular function GO:0005509 calcium ion binding
molecular function GO:0035254 glutamate receptor binding
molecular function GO:0005158 insulin receptor binding
molecular function GO:0005168 neurotrophin TRKA receptor binding
molecular function GO:0004435 phosphatidylinositol phospholipase C activity
molecular function GO:0051219 phosphoprotein binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0030971 receptor tyrosine kinase binding
cellular component GO:0005911 cell-cell junction
cellular component GO:0042995 cell projection
cellular component GO:0030136 clathrin-coated vesicle
cellular component GO:0008180 COP9 signalosome
cellular component GO:0005737 cytoplasm
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0030027 lamellipodium
cellular component GO:0005886 plasma membrane
cellular component GO:0001726 ruffle
cellular component GO:0098685 Schaffer collateral - CA1 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000340 Kaempferol 286.24
BXGC0003951 Kaempferol 3-(p-coumaroyl-glucoside) 594.52
BXGC0008167 Chrysin 254.24
BXGC0008973 6-Hydroxyluteolin 6,7,3',4'-tetramethyl ether 358.34
BXGC0015759 5,6,8,3',6'-Pentamethoxy Flavone 372.12
BXGC0033310 Epigalocatechin Gallate 458.08
BXGC0040560 5,6,7,3',4',5'-Hexamethoxyflavone 402.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein