acompound

Showing entry for Pyridine-2,3-Diol

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0042231
Compound Name	Pyridine-2,3-Diol
Structure
Formula	C5H5NO2
InchiKey	GGOZGYRTNQBSSA-UHFFFAOYSA-N
SMILES	Oc1ncccc1O
Inchi	InChI=1S/C5H5NO2/c7-4-2-1-3-6-5(4)8/h1-3,7H,(H,6,8)
IUPAC	3-hydroxy-1H-pyridin-2-one
Molecular Weight	111.03
Pubchem Id	28115
Chembl Id	CHEMBL287899

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P14920	BXGT008067	D-amino-acid oxidase	reviewed	DAO	-	-	1150	-	-

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT008067	D-amino-acid oxidase	reviewed		DAO	-	1150	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P08254	BXGT006758	Stromelysin-1	reviewed	Enzyme	MMP3	Inhibition	'='	-7	%
P14780	BXGT008053	Matrix metalloproteinase-9	reviewed	Enzyme	MMP9	Inhibition	'='	21	%
P15917	BXGT008169	Lethal factor	reviewed	-	lef	Inhibition	'='	-19	%
P08253	BXGT006757	72 kDa type IV collagenase	reviewed	Enzyme	MMP2	Inhibition	'='	-18	%
P09917	BXGT006941	Arachidonate 5-lipoxygenase	reviewed	Enzyme	ALOX5	Inhibition	'='	90	%
P22894	BXGT008815	Neutrophil collagenase	reviewed	Enzyme	MMP8	Inhibition	'='	7	%
P29477	BXGT009355	Nitric oxide synthase, inducible	reviewed	-	Nos2	Inhibition	'='	0	%
P03956	BXGT006120	Interstitial collagenase	reviewed	Enzyme	MMP1	Inhibition	'='	8	%
P14920	BXGT008067	D-amino-acid oxidase	reviewed	-	DAO	IC50	'='	1150	nM
O42713	BXGT004563	Polyphenol oxidase 2	reviewed	-	PPO2	Inhibition	'='	-9	%
Q13547	BXGT013373	Histone deacetylase 1	reviewed	Epigenetic regulator	HDAC1	IC50	'<'	20	nM
Q9UBN7	BXGT021658	Histone deacetylase 6	reviewed	Epigenetic regulator	HDAC6	Inhibition	'<'	20	%
P14920	BXGT008067	D-amino-acid oxidase	reviewed	-	DAO	IC50	-	-	-
Q9BY41	BXGT020180	Histone deacetylase 8	reviewed	Epigenetic regulator	HDAC8	Inhibition	'<'	20	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF05203	Chlamydomonas reinhardtii	Chlamydomonas reinhardtii	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}