acompound

Showing entry for D-Hydroxyglutarate

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0043436
Compound Name	D-Hydroxyglutarate
Structure
Formula	C5H8O5
InchiKey	HWXBTNAVRSUOJR-GSVOUGTGSA-N
SMILES	OC(=O)CC[C@H](C(=O)O)O
Inchi	InChI=1S/C5H8O5/c6-3(5(9)10)1-2-4(7)8/h3,6H,1-2H2,(H,7,8)(H,9,10)/t3-/m1/s1
IUPAC	(2R)-2-hydroxypentanedioic acid
Molecular Weight	148.04
Pubchem Id	439391
Chembl Id	CHEMBL1614745

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
O75164	BXGT005104	Lysine-specific demethylase 4A	reviewed	KDM4A	-	-	24000	-	-
O75164	BXGT005104	Lysine-specific demethylase 4A	reviewed	KDM4A	-	-	-	-	-
Q9NWT6	BXGT021234	Hypoxia-inducible factor 1-alpha inhibitor	reviewed	HIF1AN	-	-	1500000	-	-
Q9GYI0	BXGT020420	Lysine-specific demethylase 7 homolog	reviewed	jmjd-1.2	-	10870000	-	-	-
O14607	BXGT004075	Histone demethylase UTY	reviewed	UTY	Transcription factor	-	-	-	-
Q9UGL1	BXGT021685	Lysine-specific demethylase 5B	reviewed	KDM5B	Epigenetic regulator	-	-	-	-
Q8N371	BXGT018504	Bifunctional peptidase and arginyl-hydroxylase JMJD5	reviewed	KDM8	-	-	-	-	-

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT005104	Lysine-specific demethylase 4A	reviewed		KDM4A	-	24000	-	-
reviewed	BXGT022239	Lysine-specific demethylase 2A	reviewed		KDM2A	-	106000	-	-
reviewed	BXGT020465	Lysine-specific demethylase 4C	reviewed		KDM4C	-	79000	-	-
reviewed	BXGT020209	Alpha-ketoglutarate-dependent dioxygenase FTO	reviewed		FTO	-	>1000000	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q9H3R0	BXGT020465	Lysine-specific demethylase 4C	reviewed	-	KDM4C	IC50	'='	79000	nM
Q9Y2K7	BXGT022239	Lysine-specific demethylase 2A	reviewed	-	KDM2A	IC50	'='	106000	nM
Q9C0B1	BXGT020209	Alpha-ketoglutarate-dependent dioxygenase FTO	reviewed	-	FTO	IC50	'>'	1000000	nM
O75164	BXGT005104	Lysine-specific demethylase 4A	reviewed	-	KDM4A	IC50	'='	24000	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF05203	Chlamydomonas reinhardtii	Chlamydomonas reinhardtii	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}