Showing entry for Bifunctional peptidase and arginyl-hydroxylase JMJD5


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018504
Protein NameBifunctional peptidase and arginyl-hydroxylase JMJD5
Uniport IdQ8N371
GeneKDM8
Gene Id79831
DomainCupin_8
Pfam PF13621  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032922 circadian regulation of gene expression
Biological Process GO:0000086 G2/M transition of mitotic cell cycle
Biological Process GO:0070544 histone H3-K36 demethylation
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0031648 protein destabilization
molecular function GO:0016706 2-oxoglutarate-dependent dioxygenase activity
molecular function GO:0004177 aminopeptidase activity
molecular function GO:0003682 chromatin binding
molecular function GO:0004175 endopeptidase activity
molecular function GO:0051864 histone demethylase activity (H3-K36 specific)
molecular function GO:0046872 metal ion binding
molecular function GO:0035064 methylated histone binding
cellular component GO:0005694 chromosome
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0858252 BXGD011172 Breast adenocarcinoma Neoplasms; Skin and Connective Tissue Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000246 NG,N'G-Dimethyl-L-arginine 202.25
BXGC0000247 L-Targinine 188.23
BXGC0000436 Glycerol 92.09
BXGC0001380 Succinic acid 118.09
BXGC0002485 2-Oxopentanedioic acid 146.1
BXGC0043436 D-Hydroxyglutarate 148.04
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein