acompound

Showing entry for Kinetin

General Compound Information
BXGC Id	BXGC0046918
Compound Name	Kinetin
Structure
Formula	C10H9N5O
InchiKey	QANMHLXAZMSUEX-UHFFFAOYSA-N
SMILES	c1coc(c1)CNc1nc[nH]c2c1ncn2
Inchi	InChI=1S/C10H9N5O/c1-2-7(16-3-1)4-11-9-8-10(13-5-12-8)15-6-14-9/h1-3,5-6H,4H2,(H2,11,12,13,14,15)
IUPAC	N-(furan-2-ylmethyl)-7H-purin-6-amine
Molecular Weight	215.08
Pubchem Id	3830
Chembl Id	CHEMBL228792

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

H35

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P29029	BXGT009306	Endochitinase	reviewed	CTS1	-	3200	-	-	-
P81446	BXGT011949	Beta-galactoside-specific lectin 1	reviewed		-	-	-	-	-
Q9C5U0	BXGT020221	Histidine kinase 4	reviewed	AHK4	-	-	-	-	-
P15494	BXGT008132	Major pollen allergen Bet v 1-A	reviewed	BETVIA	-	-	-	-	-
P93330	BXGT012120	Nodulin-13	reviewed	N13	-	-	-	-	-

Binding DB

39302

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT005100	Rho-associated protein kinase 2	reviewed	Kinase	ROCK2	-	21370	-	-
reviewed	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	-	>10000	-	-
reviewed	BXGT009930	7,8-dihydro-8-oxoguanine triphosphatase	reviewed	Enzyme	NUDT1	-	20000	-	-
reviewed	BXGT009930	7,8-dihydro-8-oxoguanine triphosphatase	reviewed	Enzyme	NUDT1	-	29000	-	-
reviewed	BXGT017641	Endochitinase A1	reviewed		chiA1	-	>1000000	-	-
reviewed	BXGT009306	Endochitinase	reviewed		CTS1	3200	-	-	-
reviewed	BXGT020201	Acidic mammalian chitinase	reviewed		CHIA	-	>1000000	-	-

CHEMBL

CHEMBL228792

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P04637	BXGT006243	Cellular tumor antigen p53	reviewed	Transcription factor	TP53	Potency	'='	12589	nM
Q9NPD5	BXGT021151	Solute carrier organic anion transporter family member 1B3	reviewed	Transporter	SLCO1B3	Inhibition	'='	100	%
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	reviewed	Transcription factor	HIF1A	Potency	'='	12589	nM
P16050	BXGT008184	Arachidonate 15-lipoxygenase	reviewed	Enzyme	ALOX15	Potency	'='	25118	nM
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	819	nM
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	reviewed	-	APEX1	Potency	-	25118864	nM
Q9BZP6	BXGT020201	Acidic mammalian chitinase	reviewed	-	CHIA	IC50	'>'	1000000	nM
P16473	BXGT008234	Thyrotropin receptor	reviewed	G-protein coupled receptor	TSHR	Potency	'='	5011	nM
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	AC50	-	-	-
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	AC50	-	-	-
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	AC50	'='	7943	nM
P29029	BXGT009306	Endochitinase	reviewed	-	CTS1	Ki	'='	3200	nM
Q16637	BXGT013646	Survival motor neuron protein	reviewed	Epigenetic regulator	SMN1	Potency	'='	10000	nM
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	reviewed	-	KMT2A	Potency	'='	39810	nM
O00255	BXGT003903	Menin	reviewed	-	MEN1	Potency	'='	39810	nM
Q873Y0	BXGT017641	Endochitinase A1	reviewed	-	chiA1	IC50	'>'	1000000	nM
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	AC50	-	-	-
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	AC50	-	-	-
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	IC50	'>'	10000	nM
P81908	BXGT011959	Cholinesterase	reviewed	-	BCHE	Inhibition	'='	3	%
O42275	BXGT004559	Acetylcholinesterase	reviewed	-	ache	Inhibition	'='	-5	%
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	Inhibition	'='	96	%
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	58	nM
Q9BXM7	BXGT020172	Serine/threonine-protein kinase PINK1, mitochondrial	reviewed	Kinase	PINK1	Activity	-	-	-

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF04334	Carapichea ipecacuanha	Carapichea ipecacuanha	Medicinal Plant
BXGF04978	Isatis indigotica	Isatis indigotica	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}