Showing entry for Acidic mammalian chitinase



                       
General Target Information
BXGT IdBXGT020201
Protein NameAcidic mammalian chitinase
Uniport IdQ9BZP6
GeneCHIA
Gene Id27159
DomainCBM_14; Glyco_hydro_18
Pfam PF01607   PF00704  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00520 Amino sugar and nucleotide sugar metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006915 apoptotic process
Biological Process GO:0006032 chitin catabolic process
Biological Process GO:0006030 chitin metabolic process
Biological Process GO:0002376 immune system process
Biological Process GO:0000272 polysaccharide catabolic process
Biological Process GO:0044245 polysaccharide digestion
Biological Process GO:0090197 positive regulation of chemokine secretion
Biological Process GO:0002532 production of molecular mediator involved in inflammatory response
molecular function GO:0004568 chitinase activity
molecular function GO:0008061 chitin binding
molecular function GO:0019900 kinase binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
Reactome
Pathway Id Pathway Name
R-HSA-189085 Digestion of dietary carbohydrate
R-HSA-8935690 Digestion
R-HSA-8963743 Digestion and absorption
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000786 BXGD000010 Spontaneous abortion Female Urogenital Diseases and Pregnancy Complications
C0000822 BXGD000012 Abortion, Tubal Female Urogenital Diseases and Pregnancy Complications
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0010414 BXGD000669 Infection by Cryptococcus neoformans Infections
C0013238 BXGD000806 Dry Eye Syndromes Eye Diseases
C0015397 BXGD000983 Disorder of eye Eye Diseases
C0017152 BXGD001096 Gastritis Digestive System Diseases
C0020443 BXGD001385 Hypercholesterolemia Nutritional and Metabolic Diseases
C0022283 BXGD001533 Incontinentia Pigmenti Achromians Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0022577 BXGD001556 Keratoconjunctivitis, Vernal Eye Diseases; Immune System Diseases
C0027430 BXGD001988 Nasal Polyps Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0035204 BXGD002511 Respiration Disorders Respiratory Tract Diseases
C0035242 BXGD002521 Respiratory Tract Diseases Respiratory Tract Diseases
C0037116 BXGD002666 Silicosis Respiratory Tract Diseases; Occupational Diseases
C0155877 BXGD003830 Allergic asthma Respiratory Tract Diseases; Immune System Diseases
C0264408 BXGD005387 Childhood asthma Respiratory Tract Diseases; Immune System Diseases
C0314719 BXGD006890 Dryness of eye Eye Diseases
C0341106 BXGD007389 Eosinophilic esophagitis Digestive System Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
C0374997 BXGD007967 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
C0699949 BXGD009872 airway disease Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0729777 BXGD009934 Corneal Infection Infections; Eye Diseases
C0740903 BXGD010015 allergic symptom
C0850666 BXGD010901 Infection caused by Helicobacter pylori Infections
C1275684 BXGD012091 Meibomian gland dysfunction Eye Diseases; Skin and Connective Tissue Diseases
C1527336 BXGD013271 Sjogren's Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C1827849 BXGD013780 IgE-mediated allergic asthma Immune System Diseases
C2607914 BXGD017148 Allergic rhinitis (disorder) Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C3830362 BXGD019751 Early Pregnancy Loss Female Urogenital Diseases and Pregnancy Complications
C4524092 BXGD023092 Chronic rhinosinusitis with nasal polyps
C4552766 BXGD023523 Miscarriage Female Urogenital Diseases and Pregnancy Complications
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0046918 Kinetin 215.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein