adisease

Showing entry for Nodular Goiter

General Disease Information
BXGD Id	BXGD001164
Disease Name	Nodular Goiter
Disease CUI Id	C0018023
MeSH Codes	C19
Disease Class Name	Endocrine System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000818
Human Phenotype Ontology Term	Abnormality of the endocrine system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P02795	BXGT005968	Metallothionein-2	4502	reviewed
P04406	BXGT006207	Glyceraldehyde-3-phosphate dehydrogenase	2597	reviewed	Enzyme
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04731	BXGT006251	Metallothionein-1A	4489	reviewed
P04732	BXGT006252	Metallothionein-1E	4493	reviewed
P04733	BXGT006253	Metallothionein-1F	4494	reviewed
P07202	BXGT006565	Thyroid peroxidase	7173	reviewed	Enzyme
P07438	BXGT006625	Metallothionein-1B	4490	reviewed
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08514	BXGT006781	Integrin alpha-IIb	3674	reviewed
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P13640	BXGT007935	Metallothionein-1G	4495	reviewed
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16473	BXGT008234	Thyrotropin receptor	7253	reviewed	G-protein coupled receptor
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P36888	BXGT009938	Receptor-type tyrosine-protein kinase FLT3	2322	reviewed	Kinase
P41252	BXGT010245	Isoleucine--tRNA ligase, cytoplasmic	3376	reviewed	Enzyme
P48039	BXGT010607	Melatonin receptor type 1A	4543	reviewed	G-protein coupled receptor
P50281	BXGT010788	Matrix metalloproteinase-14	4323	reviewed	Enzyme
P60174	BXGT011294	Triosephosphate isomerase	7167	reviewed	Enzyme
P80294	BXGT011890	Metallothionein-1H	4496	reviewed
P80297	BXGT011891	Metallothionein-1X	4501	reviewed
Q8N339	BXGT018503	Metallothionein-1M	4499	reviewed
Q92911	BXGT022650	Sodium/iodide cotransporter	6528	reviewed	Transporter

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}