adisease

General Disease Information
BXGD Id	BXGD001391
Disease Name	Hypergammaglobulinemia
Disease CUI Id	C0020455
MeSH Codes	C23 C20 C15
Disease Class Name	Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0001939 HP:0002715 HP:0025354
Human Phenotype Ontology Term	Abnormality of metabolism/homeostasis; Abnormality of the immune system; Abnormal cellular phenotype
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06734	BXGT006491	Low affinity immunoglobulin epsilon Fc receptor	2208	reviewed	Receptor
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P61769	BXGT011383	Beta-2-microglobulin	567	reviewed	Immune response
Q5D1E8	BXGT015318	Endoribonuclease ZC3H12A	80149	reviewed	Nucleic acid binding
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P15260	BXGT023924	Interferon gamma receptor 1	3459	reviewed	Receptor
P19474	BXGT025520	E3 ubiquitin-protein ligase TRIM21	6737	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}