Showing entry for Lesch-Nyhan Syndrome


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001639
Disease NameLesch-Nyhan Syndrome
Disease CUI IdC0023374
MeSH Codes C16   C18   C10  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:0014667   DOID:630  
Disease Ontology Class Namedisease of metabolism; genetic disease
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
P00491 BXGT005555 Purine nucleoside phosphorylase 4860 reviewed Enzyme
P00492 BXGT005556 Hypoxanthine-guanine phosphoribosyltransferase 3251 reviewed Enzyme
P01215 BXGT005743 Glycoprotein hormones alpha chain 1081 reviewed
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P07101 BXGT006547 Tyrosine 3-monooxygenase 7054 reviewed
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P07998 BXGT006711 Ribonuclease pancreatic 6035 reviewed
P08908 BXGT006837 5-hydroxytryptamine receptor 1A 3350 reviewed G-protein coupled receptor
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P21918 BXGT008708 D(1B) dopamine receptor 1816 reviewed G-protein coupled receptor
P29274 BXGT009327 Adenosine receptor A2a 135 reviewed G-protein coupled receptor
P31939 BXGT009584 Bifunctional purine biosynthesis protein PURH 471 reviewed Enzyme
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P47989 BXGT010602 Xanthine dehydrogenase/oxidase 7498 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
Q96S37 BXGT019737 Solute carrier family 22 member 12 116085 reviewed Transporter
Q9BZ23 BXGT020194 Pantothenate kinase 2, mitochondrial 80025 reviewed Kinase
Q9NRG1 BXGT021186 Phosphoribosyltransferase domain-containing protein 1 56952 reviewed Enzyme
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 9429 reviewed Transporter
Q9Y233 BXGT022210 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 10846 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease