adisease

Showing entry for Sphingolipidoses

　　　　　　　　　　　　　　　　

General Disease Information
BXGD Id	BXGD002710
Disease Name	Sphingolipidoses
Disease CUI Id	C0037899
MeSH Codes	C16 C18 C10
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:0014667 DOID:630
Disease Ontology Class Name	disease of metabolism; genetic disease
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O15118	BXGT004127	NPC intracellular cholesterol transporter 1	4864	reviewed	Transporter
O95470	BXGT005382	Sphingosine-1-phosphate lyase 1	8879	reviewed
P05108	BXGT006317	Cholesterol side-chain cleavage enzyme, mitochondrial	1583	reviewed
P07602	BXGT006646	Prosaposin	5660	reviewed
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P16278	BXGT008213	Beta-galactosidase	2720	reviewed	Enzyme
P17405	BXGT008304	Sphingomyelin phosphodiesterase	6609	reviewed	Enzyme
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P51843	BXGT010897	Nuclear receptor subfamily 0 group B member 1	190	reviewed	Nuclear receptor
Q13285	BXGT013335	Steroidogenic factor 1	2516	reviewed	Nuclear receptor
Q14457	BXGT013472	Beclin-1	8678	reviewed	Enzyme modulator
O60502	BXGT023392	Protein O-GlcNAcase	10724	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}