adisease

Showing entry for Holt-Oram syndrome

　　　　　　　　　　　　　　　　

General Disease Information
BXGD Id	BXGD005490
Disease Name	Holt-Oram syndrome
Disease CUI Id	C0265264
MeSH Codes	C16 C05 C14
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Cardiovascular Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:630 DOID:7 DOID:225
Disease Ontology Class Name	genetic disease; disease of anatomical entity; syndrome
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O15119	BXGT004128	T-box transcription factor TBX3	6926	reviewed	Transcription factor
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P08581	BXGT006794	Hepatocyte growth factor receptor	4233	reviewed	Kinase
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P11308	BXGT007684	Transcriptional regulator ERG	2078	reviewed	Transcription factor
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P12004	BXGT007766	Proliferating cell nuclear antigen	5111	reviewed	Nucleic acid binding
P12270	BXGT007785	Nucleoprotein TPR	7175	reviewed
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P52952	BXGT010966	Homeobox protein Nkx-2.5	1482	reviewed	Transcription factor
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q99593	BXGT019939	T-box transcription factor TBX5	6910	reviewed	Transcription factor
P16284	BXGT022972	Platelet endothelial cell adhesion molecule	5175	reviewed	Cell adhesion
O15016	BXGT024295	Tripartite motif-containing protein 66	9866	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}