Showing entry for Metastatic non-small cell lung cancer


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD006620
Disease NameMetastatic non-small cell lung cancer
Disease CUI IdC0278987
MeSH Codes C04  
Disease Class NameNeoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O14757 BXGT004092 Serine/threonine-protein kinase Chk1 1111 reviewed Kinase
O43557 BXGT004600 Tumor necrosis factor ligand superfamily member 14 8740 reviewed Signaling
O94907 BXGT005340 Dickkopf-related protein 1 22943 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02741 BXGT005936 C-reactive protein 1401 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04732 BXGT006252 Metallothionein-1E 4493 reviewed
P04818 BXGT006269 Thymidylate synthase 7298 reviewed Enzyme
P05412 BXGT006354 Transcription factor AP-1 3725 reviewed Transcription factor
P06731 BXGT006488 Carcinoembryonic antigen-related cell adhesion molecule 5 1048 reviewed
P06756 BXGT006499 Integrin alpha-V 3685 reviewed
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret 5979 reviewed Kinase
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09619 BXGT006911 Platelet-derived growth factor receptor beta 5159 reviewed Kinase
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P12830 BXGT007852 Cadherin-1 999 reviewed
P14618 BXGT008027 Pyruvate kinase PKM 5315 reviewed Kinase
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16220 BXGT008206 Cyclic AMP-responsive element-binding protein 1 1385 reviewed
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P16581 BXGT008245 E-selectin 6401 reviewed
P24941 BXGT009002 Cyclin-dependent kinase 2 1017 reviewed Kinase
P30279 BXGT009415 G1/S-specific cyclin-D2 894 reviewed Enzyme modulator
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 1136 reviewed Ion channel
P33261 BXGT009707 Cytochrome P450 2C19 1557 reviewed
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 5347 reviewed Kinase
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P78358 BXGT011838 Cancer/testis antigen 1 246100 reviewed
P98066 BXGT012225 Tumor necrosis factor-inducible gene 6 protein 7130 reviewed
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q06710 BXGT012887 Paired box protein Pax-8 7849 reviewed
Q08050 BXGT012958 Forkhead box protein M1 2305 reviewed
Q12772 BXGT013262 Sterol regulatory element-binding protein 2 6721 reviewed
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q15582 BXGT013581 Transforming growth factor-beta-induced protein ig-h3 7045 reviewed Signaling
Q15759 BXGT013595 Mitogen-activated protein kinase 11 5600 reviewed Kinase
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q86SG5 BXGT017599 Protein S100-A7A 338324 reviewed
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 1244 reviewed Transporter
Q96EP1 BXGT019651 E3 ubiquitin-protein ligase CHFR 55743 reviewed Enzyme
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UM73 BXGT021773 ALK tyrosine kinase receptor 238 reviewed Kinase
Q92911 BXGT022650 Sodium/iodide cotransporter 6528 reviewed Transporter
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease