Showing entry for Paired box protein Pax-8


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012887
Protein NamePaired box protein Pax-8
Uniport IdQ06710
GenePAX8
Gene Id7849
DomainPAX; Pax2_C
Pfam PF00292   PF12403  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.2 Endocrine system hsa04918 Thyroid hormone synthesis
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
6. Human Diseases 6.1 Cancers: Overview hsa05202 Transcriptional misregulation in cancer
6. Human Diseases 6.2 Cancers: Specific types hsa05216 Thyroid cancer
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0009653 anatomical structure morphogenesis
Biological Process GO:0001658 branching involved in ureteric bud morphogenesis
Biological Process GO:0071371 cellular response to gonadotropin stimulus
Biological Process GO:0007417 central nervous system development
Biological Process GO:0042472 inner ear morphogenesis
Biological Process GO:0001822 kidney development
Biological Process GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis
Biological Process GO:0001823 mesonephros development
Biological Process GO:0072278 metanephric comma-shaped body morphogenesis
Biological Process GO:0072221 metanephric distal convoluted tubule development
Biological Process GO:0072207 metanephric epithelium development
Biological Process GO:0072289 metanephric nephron tubule formation
Biological Process GO:0072284 metanephric S-shaped body morphogenesis
Biological Process GO:1900215 negative regulation of apoptotic process involved in metanephric collecting duct development
Biological Process GO:1900218 negative regulation of apoptotic process involved in metanephric nephron tubule development
Biological Process GO:0010667 negative regulation of cardiac muscle cell apoptotic process
Biological Process GO:0072305 negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
Biological Process GO:1900212 negative regulation of mesenchymal cell apoptotic process involved in metanephros development
Biological Process GO:0071599 otic vesicle development
Biological Process GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis
Biological Process GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
Biological Process GO:2000594 positive regulation of metanephric DCT cell differentiation
Biological Process GO:2000611 positive regulation of thyroid hormone generation
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0039003 pronephric field specification
Biological Process GO:0048793 pronephros development
Biological Process GO:0042981 regulation of apoptotic process
Biological Process GO:0072307 regulation of metanephric nephron tubule epithelial cell differentiation
Biological Process GO:2000612 regulation of thyroid-stimulating hormone secretion
Biological Process GO:0006790 sulfur compound metabolic process
Biological Process GO:0030878 thyroid gland development
Biological Process GO:0006351 transcription, DNA-templated
Biological Process GO:0001655 urogenital system development
Biological Process GO:0003281 ventricular septum development
molecular function GO:0003677 DNA binding
molecular function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:1990837 sequence-specific double-stranded DNA binding
molecular function GO:0004996 thyroid-stimulating hormone receptor activity
molecular function GO:0000976 transcription regulatory region sequence-specific DNA binding
cellular component GO:0000790 nuclear chromatin
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000731 BXGD000002 Abdomen distended Digestive System Diseases
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0000846 BXGD000015 Agenesis
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001430 BXGD000054 Adenoma Neoplasms
C0002793 BXGD000130 Anaplasia Pathological Conditions, Signs and Symptoms; Neoplasms
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005845 BXGD000341 Blood urea nitrogen measurement
C0005910 BXGD000349 Body Weight Pathological Conditions, Signs and Symptoms
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006145 BXGD000376 Breast Diseases Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007115 BXGD000432 Malignant neoplasm of thyroid Neoplasms; Endocrine System Diseases
C0007130 BXGD000440 Mucinous Adenocarcinoma Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007133 BXGD000442 Carcinoma, Papillary Neoplasms
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007138 BXGD000446 Carcinoma, Transitional Cell Neoplasms
C0007140 BXGD000447 Carcinosarcoma Neoplasms
C0007789 BXGD000488 Cerebral Palsy Nervous System Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008497 BXGD000549 Choriocarcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008626 BXGD000559 Congenital chromosomal disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0009806 BXGD000633 Constipation Pathological Conditions, Signs and Symptoms
C0010308 BXGD000661 Congenital Hypothyroidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0010709 BXGD000689 Cyst Pathological Conditions, Signs and Symptoms; Neoplasms
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0014130 BXGD000899 Endocrine System Diseases Endocrine System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014534 BXGD000924 Epididymitis Male Urogenital Diseases
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0017668 BXGD001143 Focal glomerulosclerosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0018021 BXGD001162 Goiter Endocrine System Diseases
C0018213 BXGD001187 Graves Disease Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0018916 BXGD001245 Hemangioma Neoplasms
C0019207 BXGD001303 Hepatoma, Morris Digestive System Diseases; Neoplasms
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0019522 BXGD001332 Adenoma, Sweat Gland Neoplasms
C0020433 BXGD001379 Hyperbilirubinemia Pathological Conditions, Signs and Symptoms
C0020550 BXGD001429 Hyperthyroidism Endocrine System Diseases
C0020672 BXGD001461 Hypothermia, natural Pathological Conditions, Signs and Symptoms
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0022346 BXGD001537 Icterus Pathological Conditions, Signs and Symptoms
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022665 BXGD001573 Kidney Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023380 BXGD001640 Lethargy Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0023418 BXGD001642 leukemia Neoplasms
C0023462 BXGD001654 Acute Megakaryocytic Leukemias Neoplasms
C0023485 BXGD001667 Precursor B-Cell Lymphoblastic Leukemia-Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023827 BXGD001707 liposarcoma Neoplasms
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024421 BXGD001770 Macroglossia Stomatognathic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025500 BXGD001874 Mesothelioma Neoplasms
C0026827 BXGD001936 Muscle hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027708 BXGD002025 Nephroblastoma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0029925 BXGD002181 Ovarian Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0035078 BXGD002505 Kidney Failure Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0035334 BXGD002539 Retinitis Pigmentosa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0036857 BXGD002638 Severe intellectual disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0037317 BXGD002689 Sleep disturbances Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0038450 BXGD002759 Stridor Pathological Conditions, Signs and Symptoms
C0039101 BXGD002790 synovial sarcoma Neoplasms
C0040128 BXGD002844 Thyroid Diseases Endocrine System Diseases
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0040137 BXGD002846 Thyroid Nodule Neoplasms; Endocrine System Diseases
C0042392 BXGD002981 Vasitis Pathological Conditions, Signs and Symptoms
C0086692 BXGD003306 Benign Neoplasm Neoplasms
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0151468 BXGD003424 Thyroid Gland Follicular Adenoma Neoplasms; Endocrine System Diseases
C0151516 BXGD003430 Thyroid Hypoplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases
C0151747 BXGD003471 Renal tubular disorder Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0151908 BXGD003502 Dry skin Skin and Connective Tissue Diseases
C0153572 BXGD003666 Malignant Placental Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0200635 BXGD004041 Lymphocyte Count measurement
C0202239 BXGD004087 Uric acid measurement (procedure)
C0205642 BXGD004094 Adenocarcinoma, Oxyphilic Neoplasms
C0205647 BXGD004099 Follicular adenoma Neoplasms
C0205695 BXGD004106 Carcinoid, Goblet Cell Neoplasms
C0205696 BXGD004107 Anaplastic carcinoma Neoplasms
C0205698 BXGD004109 Undifferentiated carcinoma Neoplasms
C0206369 BXGD004177 Splenosis Hemic and Lymphatic Diseases; Wounds and Injuries
C0206623 BXGD004189 Adenosquamous carcinoma Neoplasms
C0206628 BXGD004193 Mesoblastic Nephroma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0206657 BXGD004220 Alveolar Soft Part Sarcoma Neoplasms
C0206675 BXGD004233 Adenomatoid Tumor Neoplasms
C0206682 BXGD004237 Follicular thyroid carcinoma Neoplasms
C0206687 BXGD004242 Carcinoma, Endometrioid Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0206693 BXGD004244 Medullary carcinoma Neoplasms
C0206695 BXGD004246 Carcinoma, Neuroendocrine Neoplasms
C0206701 BXGD004251 Cystadenocarcinoma, Serous Neoplasms
C0206704 BXGD004254 Carcinoma, Large Cell Neoplasms
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0232466 BXGD004543 Feeding difficulties
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238461 BXGD004936 Anaplastic thyroid carcinoma Neoplasms
C0238462 BXGD004937 Medullary carcinoma of thyroid Neoplasms; Endocrine System Diseases
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0242363 BXGD005156 Islet Cell Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0266283 BXGD005642 Ectopic thyroid tissue (disorder)
C0269106 BXGD006054 Endosalpingiosis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0271790 BXGD006259 Subclinical hypothyroidism Endocrine System Diseases
C0271791 BXGD006260 Severe hypothyroidism Endocrine System Diseases
C0271829 BXGD006267 Pendred's syndrome Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Endocrine System Diseases; Otorhinolaryngologic Diseases
C0278608 BXGD006549 Adult Liposarcoma Neoplasms
C0278622 BXGD006551 Adult Malignant Peripheral Nerve Sheath Tumor Neoplasms; Nervous System Diseases
C0278660 BXGD006555 Adult Synovial Sarcoma Neoplasms
C0278678 BXGD006556 Metastatic Renal Cell Cancer
C0278987 BXGD006620 Metastatic non-small cell lung cancer Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279544 BXGD006631 Adult Alveolar Soft Part Sarcoma Neoplasms
C0279671 BXGD006677 Cervical Squamous Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0279982 BXGD006702 Childhood Synovial Sarcoma Neoplasms
C0279984 BXGD006703 Childhood Liposarcoma Neoplasms
C0279985 BXGD006704 Childhood Alveolar Soft Part Sarcoma Neoplasms
C0279987 BXGD006706 Childhood Malignant Peripheral Nerve Sheath Tumor Neoplasms; Nervous System Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0334039 BXGD006981 Nephrogenic metaplasia
C0334287 BXGD007022 Fibrolamellar Hepatocellular Carcinoma Digestive System Diseases; Neoplasms
C0334361 BXGD007045 Serous surface papillary carcinoma Neoplasms
C0334488 BXGD007088 Clear cell sarcoma of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0334507 BXGD007094 Synovial sarcoma, biphasic Neoplasms
C0334663 BXGD007149 Histiocytic sarcoma Neoplasms; Hemic and Lymphatic Diseases
C0342153 BXGD007436 Congenital thyroid hypoplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases
C0342200 BXGD007444 Endemic Cretinism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346109 BXGD007779 Malignant Mesothelioma of Peritoneum Neoplasms; Respiratory Tract Diseases
C0346398 BXGD007822 Mixed follicular and papillary thyroid carcinoma
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349588 BXGD007933 Short stature
C0392485 BXGD008049 Congenital diverticulum of pharynx Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0424574 BXGD008534 Duration of sleep
C0428977 BXGD008644 Bradycardia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0456070 BXGD008863 Growth delay
C0456132 BXGD008869 Large fontanelle
C0474808 BXGD008959 Follicular neoplasm Neoplasms
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0476122 BXGD008978 ovarian serous tumor
C0541764 BXGD009259 Delayed bone age
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0557874 BXGD009444 Global developmental delay
C0586553 BXGD009609 Raised TSH level Endocrine System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0684354 BXGD009798 Benign neoplasm of sweat gland Neoplasms; Skin and Connective Tissue Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700201 BXGD009880 Dyssomnias Nervous System Diseases; Mental Disorders
C0740457 BXGD010000 Malignant neoplasm of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0749420 BXGD010216 Thyroid Agenesis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases
C0751690 BXGD010553 Malignant Peripheral Nerve Sheath Tumor Neoplasms; Nervous System Diseases
C0851578 BXGD010925 Sleep Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0862312 BXGD011259 Epithelioid mesothelioma, malignant Neoplasms
C0917799 BXGD011410 Hypersomnia Nervous System Diseases; Mental Disorders
C0917801 BXGD011412 Sleeplessness Nervous System Diseases; Mental Disorders
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1096168 BXGD011606 Chromosome 17 trisomy Pathological Conditions, Signs and Symptoms
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1261473 BXGD011855 Sarcoma Neoplasms
C1266043 BXGD011939 Sarcomatoid Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1266049 BXGD011944 Hyalinizing trabecular adenoma Neoplasms
C1266119 BXGD011964 Solitary fibrous tumor Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1300127 BXGD012268 Perivascular Epithelioid Cell Neoplasms Neoplasms
C1305855 BXGD012348 Body mass index
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1306503 BXGD012363 Congenital exomphalos Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1306837 BXGD012377 Papillary Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1321809 BXGD012442 HYPOTHYROIDISM, GOITROUS
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332900 BXGD012552 Cerebellar hemangioblastoma Neoplasms; Nervous System Diseases
C1332965 BXGD012565 Congenital Mesoblastic Nephroma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1333015 BXGD012581 Childhood Kidney Wilms Tumor Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1333375 BXGD012619 Ectopic thymus
C1335167 BXGD012768 Ovarian Mucinous Adenocarcinoma Neoplasms
C1335177 BXGD012771 Ovarian Serous Adenocarcinoma Neoplasms
C1336751 BXGD012862 Thyroid Hyalinizing Trabecular Adenoma Neoplasms; Endocrine System Diseases
C1337011 BXGD012874 Well Differentiated Pancreatic Endocrine Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1337012 BXGD012875 Well-differentiated papillary mesothelioma Neoplasms
C1337013 BXGD012876 Differentiated Thyroid Gland Carcinoma
C1368683 BXGD012900 Epithelioma Neoplasms
C1370889 BXGD012920 Liposarcoma, well differentiated Neoplasms
C1377610 BXGD012924 Peritoneal Mesothelioma Digestive System Diseases; Neoplasms
C1378703 BXGD012933 Renal carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1563716 BXGD013390 Thyroid Dysgenesis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases
C1608408 BXGD013434 Malignant transformation
C1698581 BXGD013519 Rokitansky Kuster Hauser syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C1704613 BXGD013566 Thyroid Gland Carcinoma Showing Thymus-Like Differentiation Neoplasms; Endocrine System Diseases
C1709457 BXGD013625 Papillary Thyroid Microcarcinoma Neoplasms; Endocrine System Diseases
C1845847 BXGD014760 Coarse facial features Pathological Conditions, Signs and Symptoms
C1855233 BXGD015476 Large posterior fontanelle
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1861305 BXGD016027 TARSAL-CARPAL COALITION SYNDROME Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1869118 BXGD016551 HYPOTHYROIDISM, CONGENITAL, DUE TO THYROID DYSGENESIS Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C1963094 BXGD016681 Dry Skin, CTCAE
C1970269 BXGD016828 Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Respiratory Tract Diseases; Nervous System Diseases; Endocrine System Diseases
C2145472 BXGD016931 Urothelial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2674608 BXGD017250 Feeding difficulties in infancy
C2678303 BXGD017402 Hoarse cry Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Nervous System Diseases; Otorhinolaryngologic Diseases
C2718092 BXGD017528 Acrospiroma Neoplasms
C2826323 BXGD017790 Refractory Cytopenia of Childhood
C2919142 BXGD017867 Short Stature, CTCAE
C2931367 BXGD018010 Thyroid cancer, follicular Neoplasms
C2931852 BXGD018079 Clear-cell metastatic renal cell carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2940785 BXGD018183 HYPOTHYROIDISM, CONGENITAL, NONGOITROUS, 3 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C2940786 BXGD018184 Thyroid Hormone Resistance Syndrome Endocrine System Diseases
C3714651 BXGD019423 Follicular Variant Thyroid Gland Papillary Carcinoma Neoplasms; Endocrine System Diseases
C3715197 BXGD019449 Primary congenital hypothyroidism
C3839280 BXGD019772 High grade serous carcinoma
C3839681 BXGD019779 Seromucinous borderline tumor
C3896960 BXGD020042 Childhood Pre-B Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C3896961 BXGD020043 Adult Pre-B Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4023190 BXGD021141 Thyroid hemiagenesis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4049490 BXGD021936 Extragenital endometriosis
C4287589 BXGD022469 Serous Tubal Intraepithelial Carcinoma
C4518194 BXGD023014 Epithelioid angiomyolipoma Neoplasms
C4521042 BXGD023055 Complete Trisomy 21 Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
C4551761 BXGD023405 Excessive daytime sleepiness
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4721698 BXGD023763 Metastatic Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4721779 BXGD023769 Ovarian cancer stage IV
C4722172 BXGD023791 Primary differentiated carcinoma of thyroid gland
C4722330 BXGD023801 Generalized Thyroid Hormone Resistance Endocrine System Diseases
C4723838 BXGD023809 Metastatic Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000952 6-Oxocamphor 457.91
BXGC0001428 Piperlongine 317.34
BXGC0006615 Cucurbitacin I 514.65
BXGC0006758 Cucurbitacin B 558.7
BXGC0014768 Lanatoside C 984.49
BXGC0015879 Chlorhexidine 504.2
BXGC0017277 Aurin 290.09
BXGC0017843 N-(1,2,3,10-Tetramethoxy-9-Oxo-6,7-Dihydro-5H-Benzo[A]Heptalen-7-Yl)Acetamide 399.17
BXGC0019348 Angustibalin 304.13
BXGC0022544 Digoxin 780.43
BXGC0023633 Kamebanin 334.21
BXGC0024770 Digoxigenin 390.24
BXGC0024985 (-)-Demecolcine 371.17
BXGC0026471 Coronopilin 264.14
BXGC0030138 Colchicine 399.17
BXGC0031622 Podofilox 414.13
BXGC0035872 3-[(3S,5S,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-Dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-Tetradecahydrocyclopenta[A]Phenanthren-17-Yl]-2H-Furan-5-One 374.25
BXGC0039507 Digitoxigenin 374.25
BXGC0039520 [(3Ar,4S,6Z,9E,11S,11Ar)-11-Hydroxy-6,10-Dimethyl-3-Methylidene-2,8-Dioxo-4,5,11,11A-Tetrahydro-3Ah-Cyclodeca[B]Furan-4-Yl] (E)-2-Methylbut-2-Enoate 360.16
BXGC0046996 Thioguanine 167.03
BXGC0050008 Strophanthidin 404.22
BXGC0050240 [(2R,3R,4S,6S)-6-[(2R,3S,4S,6S)-4-Hydroxy-6-[(2R,3S,4S,6R)-4-Hydroxy-6-[[(3S,5R,8R,9S,10S,13R,14S,17R)-14-Hydroxy-10,13-Dimethyl-17-(5-Oxo-2H-Furan-3-Yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-Tetradecahydrocyclopenta[A]Phenanthren-3-Yl]Oxy]-2-Methyloxan-3-Yl]O 968.5
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein