Showing entry for Giant Cell Glioblastoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD007128
Disease NameGiant Cell Glioblastoma
Disease CUI IdC0334588
MeSH Codes C04  
Disease Class NameNeoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O15151 BXGT004132 Protein Mdm4 4194 reviewed Nucleic acid binding
O43683 BXGT004614 Mitotic checkpoint serine/threonine-protein kinase BUB1 699 reviewed Kinase
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60885 BXGT004906 Bromodomain-containing protein 4 23476 reviewed Epigenetic regulator
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P06276 BXGT006430 Cholinesterase 590 reviewed
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 5292 reviewed Kinase
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P21359 BXGT008640 Neurofibromin 4763 reviewed Enzyme modulator
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P25440 BXGT009044 Bromodomain-containing protein 2 6046 reviewed Epigenetic regulator
P25963 BXGT009080 NF-kappa-B inhibitor alpha 4792 reviewed
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P43235 BXGT010368 Cathepsin K 1513 reviewed Enzyme
P46100 BXGT010508 Transcriptional regulator ATRX 546 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P51946 BXGT010907 Cyclin-H 902 reviewed Enzyme modulator
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P78504 BXGT011844 Protein jagged-1 182 reviewed
Q00534 BXGT012533 Cyclin-dependent kinase 6 1021 reviewed Kinase
Q01196 BXGT012575 Runt-related transcription factor 1 861 reviewed Transcription factor
Q04721 BXGT012777 Neurogenic locus notch homolog protein 2 4853 reviewed
Q05397 BXGT012815 Focal adhesion kinase 1 5747 reviewed Kinase
Q13002 BXGT013303 Glutamate receptor ionotropic, kainate 2 2898 reviewed Ion channel
Q14469 BXGT013473 Transcription factor HES-1 3280 reviewed Transcription factor
Q15022 BXGT013523 Polycomb protein SUZ12 23512 reviewed Nucleic acid binding
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16828 BXGT013676 Dual specificity protein phosphatase 6 1848 reviewed
Q96GD4 BXGT019667 Aurora kinase B 9212 reviewed Kinase
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9UBT6 BXGT021664 DNA polymerase kappa 51426 reviewed
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q9Y219 BXGT022206 Protein jagged-2 3714 reviewed
Q9Y6A5 BXGT022325 Transforming acidic coiled-coil-containing protein 3 10460 reviewed
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
P29590 BXGT024350 Protein PML 5371 reviewed
P16104 BXGT024571 Histone H2AX 3014 reviewed Nucleic acid binding
P21926 BXGT024578 CD9 antigen 928 reviewed
Q12888 BXGT024878 TP53-binding protein 1 7158 reviewed Epigenetic regulator
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease