Showing entry for Leukocyte adhesion deficiency type 1


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD008222
Disease NameLeukocyte adhesion deficiency type 1
Disease CUI IdC0398738
MeSH Codes C16   C20  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:630   DOID:7  
Disease Ontology Class Namegenetic disease; disease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00571 BXGT003938 ATP-dependent RNA helicase DDX3X 1654 reviewed
O15392 BXGT004162 Baculoviral IAP repeat-containing protein 5 332 reviewed Enzyme modulator
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret 5979 reviewed Kinase
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08047 BXGT006720 Transcription factor Sp1 6667 reviewed Nucleic acid binding
P08670 BXGT006810 Vimentin 7431 reviewed
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P11215 BXGT007672 Integrin alpha-M 3684 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P15153 BXGT008090 Ras-related C3 botulinum toxin substrate 2 5880 reviewed Enzyme modulator
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P20701 BXGT008591 Integrin alpha-L 3683 reviewed
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28908 BXGT009302 Tumor necrosis factor receptor superfamily member 8 943 reviewed
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P29400 BXGT009343 Collagen alpha-5(IV) chain 1287 reviewed
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P30530 BXGT009431 Tyrosine-protein kinase receptor UFO 558 reviewed Kinase
P31260 BXGT009519 Homeobox protein Hox-A10 3206 reviewed
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P62834 BXGT011464 Ras-related protein Rap-1A 5906 reviewed Enzyme modulator
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q15561 BXGT013578 Transcriptional enhancer factor TEF-3 7004 reviewed Transcription factor
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UJ41 BXGT021723 Rab5 GDP/GTP exchange factor 27342 reviewed Enzyme modulator
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q8IX03 BXGT024000 Protein KIBRA 23286 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease