Showing entry for Integrin beta-2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006316
Protein NameIntegrin beta-2
Uniport IdP05107
GeneITGB2
Gene Id3689
DomainIntegrin_beta; Integrin_b_cyt; Integrin_B_tail; PSI_integrin
Pfam PF08725   PF07965   PF00362   PF17205  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04015 Rap1 signaling pathway
4. Cellular Processes 4.1 Transport and catabolism hsa04145 Phagosome
3. Environmental Information Processing 3.2 Signal transduction hsa04390 Hippo signaling pathway
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04514 Cell adhesion molecules (CAMs)
5. Organismal Systems 5.1 Immune system hsa04610 Complement and coagulation cascades
5. Organismal Systems 5.1 Immune system hsa04650 Natural killer cell mediated cytotoxicity
5. Organismal Systems 5.1 Immune system hsa04670 Leukocyte transendothelial migration
4. Cellular Processes 4.5 Cell motility hsa04810 Regulation of actin cytoskeleton
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05133 Pertussis
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05134 Legionellosis
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05140 Leishmaniasis
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05144 Malaria
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05146 Amoebiasis
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05150 Staphylococcus aureus infection
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05152 Tuberculosis
6. Human Diseases 6.9 Infectious diseases: Viral hsa05166 Human T-cell leukemia virus 1 infection
6. Human Diseases 6.3 Immune diseases hsa05323 Rheumatoid arthritis
6. Human Diseases 6.6 Cardiovascular diseases hsa05416 Viral myocarditis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007568 aging
Biological Process GO:0097242 amyloid-beta clearance
Biological Process GO:0006915 apoptotic process
Biological Process GO:0007155 cell adhesion
Biological Process GO:0033627 cell adhesion mediated by integrin
Biological Process GO:0098609 cell-cell adhesion
Biological Process GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules
Biological Process GO:0007267 cell-cell signaling
Biological Process GO:0007160 cell-matrix adhesion
Biological Process GO:0016477 cell migration
Biological Process GO:0045123 cellular extravasation
Biological Process GO:0071404 cellular response to low-density lipoprotein particle stimulus
Biological Process GO:0019221 cytokine-mediated signaling pathway
Biological Process GO:0035987 endodermal cell differentiation
Biological Process GO:0043542 endothelial cell migration
Biological Process GO:0030198 extracellular matrix organization
Biological Process GO:0034113 heterotypic cell-cell adhesion
Biological Process GO:0006954 inflammatory response
Biological Process GO:0007229 integrin-mediated signaling pathway
Biological Process GO:0007159 leukocyte cell-cell adhesion
Biological Process GO:0050900 leukocyte migration
Biological Process GO:0002523 leukocyte migration involved in inflammatory response
Biological Process GO:0001774 microglial cell activation
Biological Process GO:0030101 natural killer cell activation
Biological Process GO:0045963 negative regulation of dopamine metabolic process
Biological Process GO:0030593 neutrophil chemotaxis
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:1990266 neutrophil migration
Biological Process GO:0006911 phagocytosis, engulfment
Biological Process GO:0045766 positive regulation of angiogenesis
Biological Process GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell
Biological Process GO:1901216 positive regulation of neuron death
Biological Process GO:0043315 positive regulation of neutrophil degranulation
Biological Process GO:0051092 positive regulation of NF-kappaB transcription factor activity
Biological Process GO:0045429 positive regulation of nitric oxide biosynthetic process
Biological Process GO:2000363 positive regulation of prostaglandin-E synthase activity
Biological Process GO:0090314 positive regulation of protein targeting to membrane
Biological Process GO:0032930 positive regulation of superoxide anion generation
Biological Process GO:0043113 receptor clustering
Biological Process GO:0031623 receptor internalization
Biological Process GO:0006898 receptor-mediated endocytosis
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:0050776 regulation of immune response
Biological Process GO:0050730 regulation of peptidyl-tyrosine phosphorylation
Biological Process GO:0034142 toll-like receptor 4 signaling pathway
molecular function GO:0001540 amyloid-beta binding
molecular function GO:0050839 cell adhesion molecule binding
molecular function GO:0001851 complement component C3b binding
molecular function GO:0031072 heat shock protein binding
molecular function GO:0030369 ICAM-3 receptor activity
molecular function GO:0005178 integrin binding
molecular function GO:0046872 metal ion binding
molecular function GO:0019901 protein kinase binding
cellular component GO:0009986 cell surface
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0070062 extracellular exosome
cellular component GO:1903561 extracellular vesicle
cellular component GO:0101003 ficolin-1-rich granule membrane
cellular component GO:0005925 focal adhesion
cellular component GO:0034687 integrin alphaL-beta2 complex
cellular component GO:0034688 integrin alphaM-beta2 complex
cellular component GO:0034689 integrin alphaX-beta2 complex
cellular component GO:0008305 integrin complex
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0044853 plasma membrane raft
cellular component GO:0043235 receptor complex
cellular component GO:0035579 specific granule membrane
cellular component GO:0070821 tertiary granule membrane
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1280218 Adaptive Immune System
R-HSA-1474244 Extracellular matrix organization
R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168898 Toll-like Receptor Cascades
R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
R-HSA-202733 Cell surface interactions at the vascular wall
R-HSA-216083 Integrin cell surface interactions
R-HSA-449147 Signaling by Interleukins
R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling
R-HSA-6798695 Neutrophil degranulation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001430 BXGD000054 Adenoma Neoplasms
C0001815 BXGD000078 Primary Myelofibrosis Hemic and Lymphatic Diseases
C0002382 BXGD000109 Alveolar Bone Loss Musculoskeletal Diseases; Stomatognathic Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002622 BXGD000119 Amnesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0002895 BXGD000152 Anemia, Sickle Cell Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0002962 BXGD000160 Angina Pectoris Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004610 BXGD000281 Bacteremia Pathological Conditions, Signs and Symptoms; Infections
C0004623 BXGD000282 Bacterial Infections Infections
C0004943 BXGD000297 Behcet Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Skin and Connective Tissue Diseases; Stomatognathic Diseases; Cardiovascular Diseases
C0005411 BXGD000313 Biliary Atresia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0005699 BXGD000325 Blast Phase Pathological Conditions, Signs and Symptoms; Neoplasms; Hemic and Lymphatic Diseases
C0005779 BXGD000336 Blood Coagulation Disorders Hemic and Lymphatic Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006413 BXGD000397 Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0006663 BXGD000403 Calcinosis Nutritional and Metabolic Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0008039 BXGD000512 Cheyne-Stokes Respiration Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0008312 BXGD000527 Primary biliary cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0008728 BXGD000567 Eosinophilic granulomatosis with polyangiitis Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010414 BXGD000669 Infection by Cryptococcus neoformans Infections
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0011265 BXGD000708 Presenile dementia Nervous System Diseases; Mental Disorders
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011603 BXGD000734 Dermatitis Skin and Connective Tissue Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0013238 BXGD000806 Dry Eye Syndromes Eye Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0014356 BXGD000910 Enterocolitis Digestive System Diseases
C0015397 BXGD000983 Disorder of eye Eye Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0017574 BXGD001122 Gingivitis Infections; Stomatognathic Diseases
C0017658 BXGD001138 Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0018133 BXGD001176 Graft-vs-Host Disease Immune System Diseases
C0018203 BXGD001184 Chronic granulomatous disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C0018213 BXGD001187 Graves Disease Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0018378 BXGD001190 Guillain-Barre Syndrome Immune System Diseases; Nervous System Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0018824 BXGD001237 Heart valve disease Cardiovascular Diseases
C0019187 BXGD001296 Hepatitis, Alcoholic Digestive System Diseases; Chemically-Induced Disorders
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0019569 BXGD001337 Hirschsprung Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0020443 BXGD001385 Hypercholesterolemia Nutritional and Metabolic Diseases
C0020445 BXGD001386 Hypercholesterolemia, Familial Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0020452 BXGD001389 Hyperemia Cardiovascular Diseases
C0020473 BXGD001396 Hyperlipidemia Nutritional and Metabolic Diseases
C0020479 BXGD001399 Hyperlipoproteinemia Type III Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0020517 BXGD001415 Hypersensitivity Immune System Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020557 BXGD001432 Hypertriglyceridemia Nutritional and Metabolic Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0021053 BXGD001476 Immune System Diseases Immune System Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0022575 BXGD001555 Keratoconjunctivitis Sicca Eye Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023223 BXGD001621 Leg Ulcer Skin and Connective Tissue Diseases
C0023290 BXGD001631 Leishmaniasis, Visceral Infections
C0023418 BXGD001642 leukemia Neoplasms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023443 BXGD001648 Hairy Cell Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023470 BXGD001659 Myeloid Leukemia Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023487 BXGD001669 Acute Promyelocytic Leukemia Neoplasms
C0023492 BXGD001671 Leukemia, T-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023493 BXGD001672 Adult T-Cell Lymphoma/Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023510 BXGD001676 Leukocyte Disorders Hemic and Lymphatic Diseases
C0023518 BXGD001677 Leukocytosis Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0023646 BXGD001690 Lichen Planus Skin and Connective Tissue Diseases
C0023860 BXGD001708 Listeriosis Infections
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024131 BXGD001736 Lupus Vulgaris Infections; Skin and Connective Tissue Diseases
C0024138 BXGD001738 Lupus Erythematosus, Discoid Skin and Connective Tissue Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024143 BXGD001741 Lupus Nephritis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases; Immune System Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024530 BXGD001783 Malaria Infections
C0024534 BXGD001784 Malaria, Cerebral Infections; Nervous System Diseases
C0024790 BXGD001804 Paroxysmal nocturnal hemoglobinuria Hemic and Lymphatic Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0025362 BXGD001866 Mental Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026948 BXGD001952 Mycosis Fungoides Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027059 BXGD001965 Myocarditis Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027697 BXGD002022 Nephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027720 BXGD002028 Nephrosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0028259 BXGD002073 Nodule
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0029882 BXGD002177 Otitis Media Otorhinolaryngologic Diseases
C0030305 BXGD002206 Pancreatitis Digestive System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031090 BXGD002280 Periodontal Diseases Stomatognathic Diseases
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0031106 BXGD002283 Aggressive Periodontitis Stomatognathic Diseases
C0032019 BXGD002321 Pituitary Neoplasms Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0032131 BXGD002330 Plasmacytoma Neoplasms; Immune System Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032300 BXGD002346 Lobar Pneumonia Infections; Respiratory Tract Diseases
C0032463 BXGD002357 Polycythemia Vera Neoplasms; Hemic and Lymphatic Diseases
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0034152 BXGD002467 Henoch-Schoenlein Purpura Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0035078 BXGD002505 Kidney Failure Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0035126 BXGD002509 Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0035204 BXGD002511 Respiration Disorders Respiratory Tract Diseases
C0035222 BXGD002513 Respiratory Distress Syndrome, Adult Respiratory Tract Diseases
C0035242 BXGD002521 Respiratory Tract Diseases Respiratory Tract Diseases
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0036323 BXGD002595 Schistosomiasis Infections
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0037299 BXGD002685 Skin Ulcer Skin and Connective Tissue Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0039101 BXGD002790 synovial sarcoma Neoplasms
C0040015 BXGD002833 Thrombasthenia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0040028 BXGD002835 Thrombocythemia, Essential Hemic and Lymphatic Diseases
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0042345 BXGD002977 Varicosity Cardiovascular Diseases
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0042384 BXGD002979 Vasculitis Cardiovascular Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079770 BXGD003098 Lymphoma, Small Noncleaved-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079773 BXGD003100 Lymphoma, T-Cell, Cutaneous Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085077 BXGD003117 Sweet Syndrome Skin and Connective Tissue Diseases
C0085096 BXGD003123 Peripheral Vascular Diseases Cardiovascular Diseases
C0085409 BXGD003168 Polyendocrinopathies, Autoimmune Immune System Diseases; Endocrine System Diseases
C0085612 BXGD003204 Ventricular arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0086981 BXGD003317 Sicca Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C0149678 BXGD003346 Epstein-Barr Virus Infections Infections
C0149770 BXGD003359 Rectal abscess Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Infections
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0149940 BXGD003391 Sciatic Neuropathy Nervous System Diseases
C0151468 BXGD003424 Thyroid Gland Follicular Adenoma Neoplasms; Endocrine System Diseases
C0151857 BXGD003488 Pleocytosis Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0153633 BXGD003674 Malignant neoplasm of brain Neoplasms; Nervous System Diseases
C0153690 BXGD003684 Secondary malignant neoplasm of bone Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0158945 BXGD003913 Congenital cytomegalovirus infection Infections
C0162442 BXGD003943 Parapsoriasis en Plaques Skin and Connective Tissue Diseases
C0162810 BXGD003982 Cicatrix, Hypertrophic Pathological Conditions, Signs and Symptoms
C0162836 BXGD003990 Hidradenitis Suppurativa Infections; Skin and Connective Tissue Diseases
C0162871 BXGD003996 Aortic Aneurysm, Abdominal Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0205698 BXGD004109 Undifferentiated carcinoma Neoplasms
C0206064 BXGD004150 Microvascular Angina Cardiovascular Diseases
C0206139 BXGD004159 Lichen Planus, Oral Skin and Connective Tissue Diseases; Stomatognathic Diseases
C0220633 BXGD004303 Uveal melanoma Neoplasms; Eye Diseases
C0221052 BXGD004380 Chronic berylliosis Pathological Conditions, Signs and Symptoms; Infections; Respiratory Tract Diseases; Occupational Diseases; Wounds and Injuries
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0235480 BXGD004751 Paroxysmal atrial fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0236642 BXGD004815 Pick Disease of the Brain Nervous System Diseases; Mental Disorders
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0240903 BXGD005061 Rheumatoid Vasculitis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Cardiovascular Diseases
C0242231 BXGD005144 Coronary Stenosis Cardiovascular Diseases
C0242381 BXGD005159 Lyme Arthritis Infections
C0242488 BXGD005170 Acute Lung Injury Respiratory Tract Diseases
C0242597 BXGD005182 Leukocyte-Adhesion Deficiency Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases
C0242966 BXGD005201 Systemic Inflammatory Response Syndrome Pathological Conditions, Signs and Symptoms
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0262975 BXGD005273 Chronic dermatitis Skin and Connective Tissue Diseases
C0262985 BXGD005277 Psoriasiform eczema Skin and Connective Tissue Diseases
C0263361 BXGD005292 Psoriasis vulgaris Skin and Connective Tissue Diseases
C0263454 BXGD005309 Chloracne Skin and Connective Tissue Diseases
C0263628 BXGD005334 Tumoral calcinosis Nutritional and Metabolic Diseases
C0264695 BXGD005414 Subendocardial ischemia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0265338 BXGD005522 Coffin-Siris syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Stomatognathic Diseases; Behavior and Behavior Mechanisms
C0272187 BXGD006318 Congenital leukocyte adherence deficiency
C0276447 BXGD006425 Rhinovirus infection Infections
C0278764 BXGD006581 Adult Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0278879 BXGD006610 Childhood Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0279646 BXGD006670 Childhood Acute Monocytic Leukemia Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280634 BXGD006753 Adult Acute Monocytic Leukemia Neoplasms
C0280803 BXGD006766 Primary central nervous system lymphoma Neoplasms; Immune System Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0282577 BXGD006816 Congenital Disorders of Glycosylation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0314719 BXGD006890 Dryness of eye Eye Diseases
C0338451 BXGD007176 Frontotemporal dementia Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C0340319 BXGD007320 Posterior myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0342257 BXGD007447 Complications of Diabetes Mellitus Endocrine System Diseases
C0342783 BXGD007550 Deficiency of butyryl-CoA dehydrogenase Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0346398 BXGD007822 Mixed follicular and papillary thyroid carcinoma
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0376618 BXGD008003 Endotoxemia Pathological Conditions, Signs and Symptoms; Infections
C0396060 BXGD008181 Congenital laryngeal adductor palsy Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Nervous System Diseases; Otorhinolaryngologic Diseases
C0398738 BXGD008222 Leukocyte adhesion deficiency type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases
C0398739 BXGD008223 Congenital disorder of glycosylation, type 2C Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0399447 BXGD008245 Early onset periodontitis Stomatognathic Diseases
C0399451 BXGD008246 Subgingival plaque Stomatognathic Diseases
C0406810 BXGD008374 Carney Complex Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Cardiovascular Diseases
C0409974 BXGD008401 Lupus Erythematosus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0423772 BXGD008505 Cutaneous Fistula Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0432408 BXGD008785 Trisomy 12 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0496899 BXGD009046 Benign neoplasm of brain, unspecified Neoplasms; Nervous System Diseases
C0497299 BXGD009059 meningitis/encephalitis
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0521174 BXGD009133 Microcalcification Nutritional and Metabolic Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0542476 BXGD009276 Forgetful Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0557874 BXGD009444 Global developmental delay
C0577631 BXGD009535 Carotid Atherosclerosis Nervous System Diseases; Cardiovascular Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0677607 BXGD009721 Hashimoto Disease Endocrine System Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699949 BXGD009872 airway disease Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0700345 BXGD009886 Candidiasis, Vulvovaginal Female Urogenital Diseases and Pregnancy Complications; Infections
C0740391 BXGD009987 Middle Cerebral Artery Occlusion Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0740457 BXGD010000 Malignant neoplasm of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0745103 BXGD010114 Hyperlipoproteinemia Type IIa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0750974 BXGD010270 Brain Tumor, Primary Neoplasms; Nervous System Diseases
C0750977 BXGD010271 Recurrent Brain Neoplasm Neoplasms; Nervous System Diseases
C0750979 BXGD010272 Primary malignant neoplasm of brain Neoplasms; Nervous System Diseases
C0751214 BXGD010353 Hyperalgesia, Thermal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751295 BXGD010383 Memory Loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0751785 BXGD010594 Unverricht-Lundborg Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0752347 BXGD010721 Lewy Body Disease Nervous System Diseases; Mental Disorders
C0856169 BXGD011096 Endothelial dysfunction
C0856737 BXGD011109 Single vessel disease Cardiovascular Diseases
C0876973 BXGD011322 Infectious Lung Disorder Infections; Respiratory Tract Diseases
C0878555 BXGD011370 Diffuse panbronchiolitis Infections; Respiratory Tract Diseases
C0887898 BXGD011401 Experimental Lung Inflammation Infections; Respiratory Tract Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0919747 BXGD011439 Cytokine storm
C0920350 BXGD011466 Autoimmune thyroiditis Immune System Diseases; Endocrine System Diseases
C0947751 BXGD011494 Vascular inflammations Cardiovascular Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1136033 BXGD011703 Cutaneous Mastocytosis Neoplasms; Skin and Connective Tissue Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1141926 BXGD011723 Abdominal sepsis
C1145670 BXGD011764 Respiratory Failure Respiratory Tract Diseases
C1264606 BXGD011914 Persistent infection Pathological Conditions, Signs and Symptoms; Infections
C1269955 BXGD012005 Tumor Cell Invasion
C1282609 BXGD012149 Granulocytosis Hemic and Lymphatic Diseases
C1292769 BXGD012230 Precursor B-cell lymphoblastic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306557 BXGD012364 Chronic venous insufficiency Cardiovascular Diseases
C1318544 BXGD012401 M5b Acute differentiated monocytic leukemia Neoplasms; Hemic and Lymphatic Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1336077 BXGD012829 Sporadic Burkitt's lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C1378703 BXGD012933 Renal carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1402315 BXGD013017 Vascular lesions
C1519653 BXGD013238 Trisomy 4 Pathological Conditions, Signs and Symptoms
C1527304 BXGD013266 Allergic Reaction Immune System Diseases
C1527336 BXGD013271 Sjogren's Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C1527390 BXGD013285 Neoplasms, Intracranial Neoplasms; Nervous System Diseases
C1536220 BXGD013341 ST segment elevation myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1608389 BXGD013432 Autoimmune myocarditis
C1719494 BXGD013655 PERIODONTITIS, LOCALIZED AGGRESSIVE Stomatognathic Diseases
C1744558 BXGD013748 T-lymphocyte deficiency
C1844383 BXGD014628 Recurrent bacterial infection Infections
C1845609 BXGD014755 Lymphoid depletion
C1851789 BXGD015233 Poor wound healing
C1852540 BXGD015290 Coronary Artery Dissection, Spontaneous Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1868683 BXGD016526 B-CELL MALIGNANCY, LOW-GRADE
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1963943 BXGD016706 Atherothrombosis
C2020625 BXGD016882 Group B Streptococcal Infection Infections
C2215101 BXGD016944 Acute cerebral ischemia Nervous System Diseases; Cardiovascular Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2242472 BXGD016973 Infection of bone Pathological Conditions, Signs and Symptoms; Infections; Musculoskeletal Diseases
C2347126 BXGD017036 Microscopic Polyarteritis Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C2676767 BXGD017344 CD59 Deficiency Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Hemic and Lymphatic Diseases
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2748536 BXGD017595 Leukocyte Adhesion Deficiency, Type III Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases
C2827407 BXGD017795 Infectious Otitis Media Otorhinolaryngologic Diseases
C2936719 BXGD018130 Mechanical Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2939465 BXGD018182 Deficiency of glucose-6-phosphate dehydrogenase Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C2945695 BXGD018187 Limb ischemia
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3275069 BXGD018658 Chronic Total Occlusion Vessel
C3536663 BXGD019068 Acute deep venous thrombosis Cardiovascular Diseases
C3665444 BXGD019288 Neutrophilia (disorder) Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C3714514 BXGD019409 Infection Infections
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C3875321 BXGD019874 Inflammatory dermatosis Skin and Connective Tissue Diseases
C4024862 BXGD021444 Recurrent staphylococcal infections
C4025198 BXGD021588 Recurrent gram-negative bacterial infections
C4048329 BXGD021904 Immunosuppression
C4083008 BXGD022100 Guillain-Barre Syndrome, Familial Immune System Diseases; Nervous System Diseases
C4087338 BXGD022143 Mite allergy
C4285778 BXGD022452 Systemic bacterial infection
C4509226 BXGD022972 Heart failure with preserved ejection fraction [HFpEF]
C4520983 BXGD023052 Congenital atresia of extrahepatic bile duct Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C4521042 BXGD023055 Complete Trisomy 21 Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4529962 BXGD023178 Fatty Liver Disease
C4703473 BXGD023650 Atherosclerotic lesion Cardiovascular Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4743661 BXGD023935 Leukocyte Adhesion Deficiency Type 3
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
BXGC0031514 Sampangine 232.06
BXGC0041900 Cytochalasin B 479.27
BXGC0042513 Simalikalactone D 478.22
BXGC0051398 Indole 117.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein