adisease

Showing entry for CADASIL Syndrome

General Disease Information
BXGD Id	BXGD010513
Disease Name	CADASIL Syndrome
Disease CUI Id	C0751587
MeSH Codes	C23 C16 C10 C14
Disease Class Name	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Cardiovascular Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:630 DOID:7
Disease Ontology Class Name	genetic disease; disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00555	BXGT003936	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	773	reviewed	Ion channel
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P02462	BXGT005881	Collagen alpha-1(IV) chain	1282	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02743	BXGT005937	Serum amyloid P-component	325	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P04070	BXGT006143	Vitamin K-dependent protein C	5624	reviewed	Enzyme
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P07204	BXGT006567	Thrombomodulin	7056	reviewed
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P10619	BXGT007589	Lysosomal protective protein	5476	reviewed	Enzyme
P10909	BXGT007630	Clusterin	1191	reviewed
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P39060	BXGT010088	Collagen alpha-1(XVIII) chain	80781	reviewed
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P78504	BXGT011844	Protein jagged-1	182	reviewed
Q04721	BXGT012777	Neurogenic locus notch homolog protein 2	4853	reviewed
Q92743	BXGT019368	Serine protease HTRA1	5654	reviewed	Enzyme
Q9UM47	BXGT021772	Neurogenic locus notch homolog protein 3	4854	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}