Showing entry for Serum amyloid P-component


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005937
Protein NameSerum amyloid P-component
Uniport IdP02743
GeneAPCS
Gene Id325
DomainPentaxin
Pfam PF00354  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006953 acute-phase response
Biological Process GO:0044267 cellular protein metabolic process
Biological Process GO:0051131 chaperone-mediated protein complex assembly
Biological Process GO:0006958 complement activation, classical pathway
Biological Process GO:0045087 innate immune response
Biological Process GO:0044869 negative regulation by host of viral exo-alpha-sialidase activity
Biological Process GO:0044871 negative regulation by host of viral glycoprotein metabolic process
Biological Process GO:0044793 negative regulation by host of viral process
Biological Process GO:0002674 negative regulation of acute inflammatory response
Biological Process GO:1903016 negative regulation of exo-alpha-sialidase activity
Biological Process GO:1903019 negative regulation of glycoprotein metabolic process
Biological Process GO:0045656 negative regulation of monocyte differentiation
Biological Process GO:0046597 negative regulation of viral entry into host cell
Biological Process GO:0048525 negative regulation of viral process
Biological Process GO:0061045 negative regulation of wound healing
Biological Process GO:0006457 protein folding
molecular function GO:0005509 calcium ion binding
molecular function GO:0030246 carbohydrate binding
molecular function GO:0001849 complement component C1q complex binding
molecular function GO:0042802 identical protein binding
molecular function GO:0030169 low-density lipoprotein particle binding
molecular function GO:0051082 unfolded protein binding
molecular function GO:0046790 virion binding
cellular component GO:0072562 blood microparticle
cellular component GO:0062023 collagen-containing extracellular matrix
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-392499 Metabolism of proteins
R-HSA-977225 Amyloid fiber formation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001339 BXGD000041 Acute pancreatitis Digestive System Diseases
C0001768 BXGD000075 Agammaglobulinemia Immune System Diseases; Hemic and Lymphatic Diseases
C0002066 BXGD000101 Alkaptonuria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0002793 BXGD000130 Anaplasia Pathological Conditions, Signs and Symptoms; Neoplasms
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0002965 BXGD000162 Angina, Unstable Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004623 BXGD000282 Bacterial Infections Infections
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006413 BXGD000397 Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0006840 BXGD000409 Candidiasis Infections
C0006846 BXGD000411 Cutaneous Candidiasis Infections; Skin and Connective Tissue Diseases
C0006849 BXGD000413 Oral candidiasis Infections; Stomatognathic Diseases
C0006852 BXGD000414 Candidiasis of vagina Female Urogenital Diseases and Pregnancy Complications; Infections
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0009447 BXGD000613 Common Variable Immunodeficiency Immune System Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010200 BXGD000653 Coughing Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013374 BXGD000824 Dysgammaglobulinemia Immune System Diseases; Hemic and Lymphatic Diseases
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0016514 BXGD001066 Foot-and-Mouth Disease Infections; Animal Diseases
C0017205 BXGD001105 Gaucher Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0017601 BXGD001125 Glaucoma Eye Diseases
C0017658 BXGD001138 Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019061 BXGD001273 Hemolytic-Uremic Syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Hemic and Lymphatic Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0020192 BXGD001364 Hyaline Membrane Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0021053 BXGD001476 Immune System Diseases Immune System Diseases
C0021345 BXGD001497 Infectious Mononucleosis Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023212 BXGD001616 Left-Sided Heart Failure Cardiovascular Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023462 BXGD001654 Acute Megakaryocytic Leukemias Neoplasms
C0023827 BXGD001707 liposarcoma Neoplasms
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024291 BXGD001757 Lymphohistiocytosis, Hemophagocytic Hemic and Lymphatic Diseases
C0027441 BXGD001991 Nasopharyngitis Infections; Respiratory Tract Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028960 BXGD002101 Oligospermia Male Urogenital Diseases
C0029227 BXGD002123 Delirium, Dementia, Amnestic, Cognitive Disorders Mental Disorders
C0030299 BXGD002205 Pancreatic Pseudocyst Digestive System Diseases; Neoplasms
C0030305 BXGD002206 Pancreatitis Digestive System Diseases
C0031069 BXGD002279 Familial Mediterranean Fever Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0032969 BXGD002385 Pregnancy in Diabetics Female Urogenital Diseases and Pregnancy Complications
C0033375 BXGD002405 Prolactinoma Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0035222 BXGD002513 Respiratory Distress Syndrome, Adult Respiratory Tract Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0042164 BXGD002965 Uveitis Eye Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085220 BXGD003142 Cerebral Amyloid Angiopathy Nutritional and Metabolic Diseases; Nervous System Diseases; Cardiovascular Diseases
C0085679 BXGD003235 Hyperchloremia Nutritional and Metabolic Diseases
C0086438 BXGD003283 Hypogammaglobulinemia Immune System Diseases; Hemic and Lymphatic Diseases
C0149678 BXGD003346 Epstein-Barr Virus Infections Infections
C0151650 BXGD003454 Renal fibrosis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0153252 BXGD003616 Systemic candidiasis Infections
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0162534 BXGD003953 Prion Diseases Infections; Nervous System Diseases
C0206247 BXGD004174 Amyloid Neuropathies Nutritional and Metabolic Diseases; Nervous System Diseases
C0221014 BXGD004364 Reactive systemic amyloidosis Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0235527 BXGD004753 Heart Failure, Right-Sided Cardiovascular Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242994 BXGD005205 Hantavirus Infections Infections
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0268380 BXGD005921 Systemic amyloidosis Nutritional and Metabolic Diseases
C0268382 BXGD005923 Amyloid nephropathy Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0268392 BXGD005930 Localized amyloidosis Nutritional and Metabolic Diseases
C0276680 BXGD006443 Infection by Candida albicans Infections
C0278764 BXGD006581 Adult Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0278879 BXGD006610 Childhood Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0281479 BXGD006776 Primary Systemic Amyloidosis Neoplasms; Nutritional and Metabolic Diseases; Immune System Diseases
C0340288 BXGD007316 Stable angina Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346302 BXGD007807 Growth Hormone-Secreting Pituitary Adenoma Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0406775 BXGD008371 Symmetrical dyschromatosis of extremities Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0520679 BXGD009101 Sleep Apnea, Obstructive Respiratory Tract Diseases; Nervous System Diseases
C0521158 BXGD009130 Recurrent tumor
C0549463 BXGD009382 X-Linked Lymphoproliferative Disorder Immune System Diseases; Hemic and Lymphatic Diseases
C0677932 BXGD009736 Progressive Neoplastic Disease
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0685898 BXGD009826 Food anaphylaxis Digestive System Diseases; Immune System Diseases
C0700345 BXGD009886 Candidiasis, Vulvovaginal Female Urogenital Diseases and Pregnancy Complications; Infections
C0744421 BXGD010095 Immune-complex glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0748355 BXGD010195 Acute respiratory distress Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0751587 BXGD010513 CADASIL Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Cardiovascular Diseases
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C0948089 BXGD011504 Acute Coronary Syndrome Cardiovascular Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1328840 BXGD012474 Autoimmune Lymphoproliferative Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1442907 BXGD013063 Foreign body giant cell granuloma Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases; Wounds and Injuries
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1536220 BXGD013341 ST segment elevation myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1536222 BXGD013343 Non STEMI
C1611743 BXGD013456 Familial (FPAH)
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1842937 BXGD014546 AURAL ATRESIA, CONGENITAL Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1845076 BXGD014708 Lymphoproliferative Syndrome, X-Linked, 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1959583 BXGD016637 Myocardial Failure Cardiovascular Diseases
C1961112 BXGD016674 Heart Decompensation Cardiovascular Diseases
C2062441 BXGD016897 Influenza A
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2242528 BXGD016976 Non-erosive reflux disease
C2931071 BXGD017950 Dianzani autoimmune lymphoproliferative syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C2936349 BXGD018109 Plaque, Amyloid Pathological Conditions, Signs and Symptoms
C2936664 BXGD018125 Acquired Hypogammaglobulinemia Immune System Diseases
C2936719 BXGD018130 Mechanical Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C3160886 BXGD018488 Non ST segment elevation acute coronary syndrome
C3536715 BXGD019070 AA amyloidosis Nutritional and Metabolic Diseases
C3539781 BXGD019086 Progressive cGVHD
C3714514 BXGD019409 Infection Infections
C3887558 BXGD019899 Hemophagocytic Syndrome Hemic and Lymphatic Diseases
C3887645 BXGD019910 Job Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C4041080 BXGD021873 Neurocognitive Disorders Mental Disorders
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002586 Calcium 40.08
BXGC0002616 Copper 63.55
BXGC0002682 Zinc 65.41
BXGC0004277 Acetic acid 60.05
BXGC0018397 beta-1,4-mannan 180.06
BXGC0039168 phosphorylethanolamine 141.02
BXGC0049447 acetate 59.01
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein