adisease

Showing entry for Cognitive deterioration

General Disease Information
BXGD Id	BXGD011005
Disease Name	Cognitive deterioration
Disease CUI Id	C0854193
MeSH Codes
Disease Class Name
Semantic Type	Mental or Behavioral Dysfunction
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
P00491	BXGT005555	Purine nucleoside phosphorylase	4860	reviewed	Enzyme
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P06276	BXGT006430	Cholinesterase	590	reviewed
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13489	BXGT007913	Ribonuclease inhibitor	6050	reviewed	Transcription factor
P14735	BXGT008042	Insulin-degrading enzyme	3416	reviewed	Enzyme
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P20591	BXGT008586	Interferon-induced GTP-binding protein Mx1	4599	reviewed	Enzyme modulator
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P22303	BXGT008751	Acetylcholinesterase	43	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P40933	BXGT010209	Interleukin-15	3600	reviewed
P42858	BXGT010341	Huntingtin	3064	reviewed
P49768	BXGT010740	Presenilin-1	5663	reviewed	Enzyme
P50406	BXGT010796	5-hydroxytryptamine receptor 6	3362	reviewed	G-protein coupled receptor
Q13478	BXGT013362	Interleukin-18 receptor 1	8809	reviewed	Receptor
Q15109	BXGT013537	Advanced glycosylation end product-specific receptor	177	reviewed	Receptor
Q9Y6A2	BXGT022324	Cholesterol 24-hydroxylase	10858	reviewed	Enzyme
Q9UBP0	BXGT023601	Spastin	6683	reviewed	Cellular structure

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}