Showing entry for Polyp of large intestine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD011568
Disease NamePolyp of large intestine
Disease CUI IdC0949059
MeSH Codes C23   C06   C04  
Disease Class NamePathological Conditions, Signs and Symptoms; Digestive System Diseases; Neoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id HP:0025031   HP:0002664  
Human Phenotype Ontology TermAbnormality of the digestive system; Neoplasm
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O15075 BXGT004124 Serine/threonine-protein kinase DCLK1 9201 reviewed Kinase
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
P00326 BXGT005499 Alcohol dehydrogenase 1C 126 reviewed Enzyme
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02741 BXGT005936 C-reactive protein 1401 reviewed
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05177 BXGT006336 Cytochrome P450 1A2 1544 reviewed Enzyme
P06730 BXGT006487 Eukaryotic translation initiation factor 4E 1977 reviewed Nucleic acid binding
P07099 BXGT006546 Epoxide hydrolase 1 2052 reviewed
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08263 BXGT006759 Glutathione S-transferase A1 2938 reviewed
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14550 BXGT008019 Aldo-keto reductase family 1 member A1 10327 reviewed Enzyme
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P18440 BXGT008404 Arylamine N-acetyltransferase 1 9 reviewed Enzyme
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P19971 BXGT008537 Thymidine phosphorylase 1890 reviewed Enzyme
P23219 BXGT008837 Prostaglandin G/H synthase 1 5742 reviewed Enzyme
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P28161 BXGT009234 Glutathione S-transferase Mu 2 2946 reviewed
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P36894 BXGT009939 Bone morphogenetic protein receptor type-1A 657 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P52569 BXGT010934 Cationic amino acid transporter 2 6542 reviewed Transporter
P52701 BXGT010943 DNA mismatch repair protein Msh6 2956 reviewed Nucleic acid binding
P54278 BXGT011038 Mismatch repair endonuclease PMS2 5395 reviewed Nucleic acid binding
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
Q12908 BXGT013278 Ileal sodium/bile acid cotransporter 6555 reviewed Transporter
Q13153 BXGT013319 Serine/threonine-protein kinase PAK 1 5058 reviewed Kinase
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q14145 BXGT013448 Kelch-like ECH-associated protein 1 9817 reviewed
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q16647 BXGT013648 Prostacyclin synthase 5740 reviewed
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q8WTS6 BXGT018986 Histone-lysine N-methyltransferase SETD7 80854 reviewed Epigenetic regulator
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q9BXH1 BXGT020167 Bcl-2-binding component 3 27113 reviewed
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NUB1 BXGT021215 Acetyl-coenzyme A synthetase 2-like, mitochondrial 84532 reviewed Enzyme
Q9UIF7 BXGT021717 Adenine DNA glycosylase 4595 reviewed Enzyme
Q9UPY3 BXGT021802 Endoribonuclease Dicer 23405 reviewed Enzyme
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
P00395 BXGT023596 Cytochrome c oxidase subunit 1 4512 reviewed Enzyme
P19474 BXGT025520 E3 ubiquitin-protein ligase TRIM21 6737 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease