Showing entry for Cationic amino acid transporter 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010934
Protein NameCationic amino acid transporter 2
Uniport IdP52569
GeneSLC7A2
Gene Id6542
Domain_permease_2; _permease_C
Pfam PF13520   PF13906  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0089718 amino acid import across plasma membrane
Biological Process GO:0006865 amino acid transport
Biological Process GO:1902475 L-alpha-amino acid transmembrane transport
Biological Process GO:0015807 L-amino acid transport
Biological Process GO:0097638 L-arginine import across plasma membrane
Biological Process GO:1903352 L-ornithine transmembrane transport
Biological Process GO:0042116 macrophage activation
Biological Process GO:0006809 nitric oxide biosynthetic process
Biological Process GO:0002537 nitric oxide production involved in inflammatory response
Biological Process GO:0050727 regulation of inflammatory response
Biological Process GO:0043030 regulation of macrophage activation
Biological Process GO:0150104 transport across blood-brain barrier
molecular function GO:0015171 amino acid transmembrane transporter activity
molecular function GO:0015181 arginine transmembrane transporter activity
molecular function GO:0015174 basic amino acid transmembrane transporter activity
molecular function GO:0015179 L-amino acid transmembrane transporter activity
molecular function GO:0061459 L-arginine transmembrane transporter activity
molecular function GO:0015189 L-lysine transmembrane transporter activity
molecular function GO:0000064 L-ornithine transmembrane transporter activity
cellular component GO:0030054 cell junction
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011127 BXGD000699 Pressure Ulcer Skin and Connective Tissue Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0019357 BXGD001326 Keratitis, Herpetic Infections; Eye Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0022578 BXGD001557 Keratoconus Eye Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037284 BXGD002679 Skin lesion Skin and Connective Tissue Diseases
C0041327 BXGD002916 Tuberculosis, Pulmonary Infections; Respiratory Tract Diseases
C0041834 BXGD002935 Erythema Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0086543 BXGD003294 Cataract Eye Diseases
C0201874 BXGD004054 Amino acids measurement
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0267375 BXGD005742 Chronic colitis Digestive System Diseases
C0268647 BXGD006024 Lysinuric Protein Intolerance Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0428883 BXGD008639 Diastolic blood pressure
C0521707 BXGD009166 Bilateral cataracts (disorder) Eye Diseases
C0523801 BXGD009219 Ornithine measurement
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0877173 BXGD011340 Food aversion
C0949059 BXGD011568 Polyp of large intestine Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000218 L-Lysine 146.19
BXGC0052927 Ornithine 132.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein