Showing entry for Potassium channel subfamily K member 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT003888
Protein NamePotassium channel subfamily K member 1
Uniport IdO00180
GeneKCNK1
Gene Id3775
DomainIon_trans_2
Pfam PF07885  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0061337 cardiac conduction
Biological Process GO:0071805 potassium ion transmembrane transport
Biological Process GO:0006813 potassium ion transport
Biological Process GO:0060075 regulation of resting membrane potential
Biological Process GO:0035094 response to nicotine
Biological Process GO:0035725 sodium ion transmembrane transport
Biological Process GO:0030322 stabilization of membrane potential
molecular function GO:0042802 identical protein binding
molecular function GO:0005242 inward rectifier potassium channel activity
molecular function GO:0005267 potassium channel activity
molecular function GO:0022841 potassium ion leak channel activity
molecular function GO:0005272 sodium channel activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0031526 brush border membrane
cellular component GO:0030425 dendrite
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:1902937 inward rectifier potassium channel complex
cellular component GO:0043204 perikaryon
cellular component GO:0005886 plasma membrane
cellular component GO:0034705 potassium channel complex
cellular component GO:0055037 recycling endosome
cellular component GO:0097060 synaptic membrane
cellular component GO:0008076 voltage-gated potassium channel complex
Reactome
Pathway Id Pathway Name
R-HSA-112316 Neuronal System
R-HSA-1296071 Potassium Channels
R-HSA-1296346 Tandem pore domain potassium channels
R-HSA-1299308 Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)
R-HSA-397014 Muscle contraction
R-HSA-5576886 Phase 4 - resting membrane potential
R-HSA-5576891 Cardiac conduction
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001849 BXGD000084 AIDS Dementia Complex Infections; Immune System Diseases; Nervous System Diseases; Mental Disorders
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0011053 BXGD000694 Deafness Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0017638 BXGD001132 Glioma Neoplasms
C0018824 BXGD001237 Heart valve disease Cardiovascular Diseases
C0020507 BXGD001413 Hyperplasia Pathological Conditions, Signs and Symptoms
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0266929 BXGD005722 Chronic Periodontitis Stomatognathic Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1142166 BXGD011736 Brugada Syndrome (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1301034 BXGD012282 Pancreatic intraepithelial neoplasia Neoplasms
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002591 Potassium 39.1
BXGC0003220 Undecane 156.31
BXGC0035201 Quinidine 324.18
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein