Showing entry for Eukaryotic translation initiation factor 3 subunit F


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT003906
Protein NameEukaryotic translation initiation factor 3 subunit F
Uniport IdO00303
GeneEIF3F
Gene Id8665
DomainJAB; MitMem_reg
Pfam PF01398   PF13012  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.2 Translation hsa03013 RNA transport
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0001732 formation of cytoplasmic translation initiation complex
Biological Process GO:0075522 IRES-dependent viral translational initiation
Biological Process GO:0016579 protein deubiquitination
Biological Process GO:0006413 translational initiation
molecular function GO:0042802 identical protein binding
molecular function GO:0070122 isopeptidase activity
molecular function GO:0008237 metallopeptidase activity
molecular function GO:0004843 thiol-dependent ubiquitin-specific protease activity
molecular function GO:0003743 translation initiation factor activity
molecular function GO:0031369 translation initiation factor binding
molecular function GO:0101005 ubiquitinyl hydrolase activity
cellular component GO:0005829 cytosol
cellular component GO:0016282 eukaryotic 43S preinitiation complex
cellular component GO:0033290 eukaryotic 48S preinitiation complex
cellular component GO:0005852 eukaryotic translation initiation factor 3 complex
cellular component GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m
cellular component GO:0016020 membrane
Reactome
Pathway Id Pathway Name
R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-392499 Metabolism of proteins
R-HSA-72613 Eukaryotic Translation Initiation
R-HSA-72649 Translation initiation complex formation
R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-HSA-72702 Ribosomal scanning and start codon recognition
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72737 Cap-dependent Translation Initiation
R-HSA-72766 Translation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1837454 BXGD014232 SPINOCEREBELLAR ATAXIA 8 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C2938924 BXGD018167 Oestrogen receptor positive breast cancer
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4749019 BXGD024046 INTELLECTUAL DEVELOPMENTAL DISORDER, AUTOSOMAL RECESSIVE 67
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0005683 Quercetin 302.24
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein