Showing entry for DNA-directed RNA polymerase, mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT003917
Protein NameDNA-directed RNA polymerase, mitochondrial
Uniport IdO00411
GenePOLRMT
Gene Id5442
DomainRNA_pol; RPOL_N
Pfam PF00940   PF14700  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006390 mitochondrial transcription
Biological Process GO:0007005 mitochondrion organization
Biological Process GO:0006391 transcription initiation from mitochondrial promoter
molecular function GO:0003899 DNA-directed 5'-3' RNA polymerase activity
molecular function GO:0001018 mitochondrial promoter sequence-specific DNA binding
molecular function GO:0003723 RNA binding
molecular function GO:0043565 sequence-specific DNA binding
cellular component GO:0034245 mitochondrial DNA-directed RNA polymerase complex
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0042645 mitochondrial nucleoid
cellular component GO:0005739 mitochondrion
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
R-HSA-1592230 Mitochondrial biogenesis
R-HSA-163282 Mitochondrial transcription initiation
R-HSA-1852241 Organelle biogenesis and maintenance
R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis
R-HSA-74160 Gene expression (Transcription)
R-HSA-75944 Transcription from mitochondrial promoters
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0023531 BXGD001684 Leukoplakia Pathological Conditions, Signs and Symptoms; Neoplasms
C0023532 BXGD001685 Leukoplakia, Oral Pathological Conditions, Signs and Symptoms; Neoplasms; Stomatognathic Diseases
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0162674 BXGD003973 Chronic progressive external ophthalmoplegia Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Eye Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein