adisease

Showing entry for Leukoplakia, Oral

General Disease Information
BXGD Id	BXGD001685
Disease Name	Leukoplakia, Oral
Disease CUI Id	C0023532
MeSH Codes	C23 C04 C07
Disease Class Name	Pathological Conditions, Signs and Symptoms; Neoplasms; Stomatognathic Diseases
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id	HP:0000152
Human Phenotype Ontology Term	Abnormality of head or neck
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00411	BXGT003917	DNA-directed RNA polymerase, mitochondrial	5442	reviewed	Enzyme
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O15527	BXGT004176	N-glycosylase/DNA lyase	4968	reviewed
O15553	BXGT004181	Pyrin	4210	reviewed
O43353	BXGT004589	Receptor-interacting serine/threonine-protein kinase 2	8767	reviewed	Kinase
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O96017	BXGT005415	Serine/threonine-protein kinase Chk2	11200	reviewed	Kinase
P00352	BXGT005510	Retinal dehydrogenase 1	216	reviewed	Enzyme
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02533	BXGT005887	Keratin, type I cytoskeletal 14	3861	reviewed
P02538	BXGT005888	Keratin, type II cytoskeletal 6A	3853	reviewed
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P05091	BXGT006312	Aldehyde dehydrogenase, mitochondrial	217	reviewed	Enzyme
P05181	BXGT006337	Cytochrome P450 2E1	1571	reviewed
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08581	BXGT006794	Hepatocyte growth factor receptor	4233	reviewed	Kinase
P08670	BXGT006810	Vimentin	7431	reviewed
P08779	BXGT006824	Keratin, type I cytoskeletal 16	3868	reviewed
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09382	BXGT006882	Galectin-1	3956	reviewed	Signaling
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P13645	BXGT007936	Keratin, type I cytoskeletal 10	3858	reviewed
P13647	BXGT007937	Keratin, type II cytoskeletal 5	3852	reviewed
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16455	BXGT008229	Methylated-DNA--protein-cysteine methyltransferase	4255	reviewed
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P18440	BXGT008404	Arylamine N-acetyltransferase 1	9	reviewed	Enzyme
P18887	BXGT008437	DNA repair protein XRCC1	7515	reviewed
P21266	BXGT008632	Glutathione S-transferase Mu 3	2947	reviewed
P21673	BXGT008676	Diamine acetyltransferase 1	6303	reviewed
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P25963	BXGT009080	NF-kappa-B inhibitor alpha	4792	reviewed
P26358	BXGT009104	DNA (cytosine-5)-methyltransferase 1	1786	reviewed	Epigenetic regulator
P28161	BXGT009234	Glutathione S-transferase Mu 2	2946	reviewed
P29033	BXGT009308	Gap junction beta-2 protein	2706	reviewed	Cell-cell junction
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P31997	BXGT009593	Carcinoembryonic antigen-related cell adhesion molecule 8	1088	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P36551	BXGT009927	Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial	1371	reviewed	Enzyme
P40692	BXGT010195	DNA mismatch repair protein Mlh1	4292	reviewed	Nucleic acid binding
P46527	BXGT010525	Cyclin-dependent kinase inhibitor 1B	1027	reviewed
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P49917	BXGT010765	DNA ligase 4	3981	reviewed
P57059	BXGT011210	Serine/threonine-protein kinase SIK1	150094	reviewed
P60022	BXGT011285	Beta-defensin 1	1672	reviewed
P61024	BXGT011350	Cyclin-dependent kinases regulatory subunit 1	1163	reviewed	Enzyme modulator
P61626	BXGT011382	Lysozyme C	4069	reviewed
P62753	BXGT011454	40S ribosomal protein S6	6194	reviewed	Nucleic acid binding
P68371	BXGT011597	Tubulin beta-4B chain	10383	reviewed	Cellular structure
Q00987	BXGT012559	E3 ubiquitin-protein ligase Mdm2	4193	reviewed	Nucleic acid binding
Q06830	BXGT012894	Peroxiredoxin-1	5052	reviewed	Enzyme
Q07812	BXGT012940	Apoptosis regulator BAX	581	reviewed	Signaling
Q08188	BXGT012965	Protein-glutamine gamma-glutamyltransferase E	7053	reviewed	Enzyme
Q08722	BXGT013002	Leukocyte surface antigen CD47	961	reviewed
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q16620	BXGT013645	BDNF/NT-3 growth factors receptor	4915	reviewed	Kinase
Q16678	BXGT013656	Cytochrome P450 1B1	1545	reviewed	Enzyme
Q99683	BXGT019947	Mitogen-activated protein kinase kinase kinase 5	4217	reviewed	Kinase
Q9BQ65	BXGT020107	U6 snRNA phosphodiesterase	79650	reviewed
Q9NP58	BXGT021143	ATP-binding cassette sub-family B member 6, mitochondrial	10058	reviewed	Transporter
Q9NR12	BXGT021174	PDZ and LIM domain protein 7	9260	reviewed	Cellular structure
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UBC3	BXGT021650	DNA (cytosine-5)-methyltransferase 3B	1789	reviewed
Q9Y239	BXGT022213	Nucleotide-binding oligomerization domain-containing protein 1	10392	reviewed	Enzyme
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q9Y6K1	BXGT022331	DNA (cytosine-5)-methyltransferase 3A	1788	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}