adisease

Showing entry for Leukoplakia

General Disease Information
BXGD Id	BXGD001684
Disease Name	Leukoplakia
Disease CUI Id	C0023531
MeSH Codes	C23 C04
Disease Class Name	Pathological Conditions, Signs and Symptoms; Neoplasms
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00411	BXGT003917	DNA-directed RNA polymerase, mitochondrial	5442	reviewed	Enzyme
O15350	BXGT004154	Tumor protein p73	7161	reviewed	Transcription factor
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P02462	BXGT005881	Collagen alpha-1(IV) chain	1282	reviewed
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P05181	BXGT006337	Cytochrome P450 2E1	1571	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P18440	BXGT008404	Arylamine N-acetyltransferase 1	9	reviewed	Enzyme
P18887	BXGT008437	DNA repair protein XRCC1	7515	reviewed
P21266	BXGT008632	Glutathione S-transferase Mu 3	2947	reviewed
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P22607	BXGT008784	Fibroblast growth factor receptor 3	2261	reviewed	Kinase
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P26447	BXGT009114	Protein S100-A4	6275	reviewed	Calcium-binding protein
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35613	BXGT009856	Basigin	682	reviewed
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P38936	BXGT010074	Cyclin-dependent kinase inhibitor 1	1026	reviewed
P40692	BXGT010195	DNA mismatch repair protein Mlh1	4292	reviewed	Nucleic acid binding
P43246	BXGT010371	DNA mismatch repair protein Msh2	4436	reviewed	Nucleic acid binding
P45452	BXGT010462	Collagenase 3	4322	reviewed	Enzyme
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P49789	BXGT010742	Bis(5'-adenosyl)-triphosphatase	2272	reviewed
P49959	BXGT010766	Double-strand break repair protein MRE11	4361	reviewed
P55210	BXGT011110	Caspase-7	840	reviewed	Enzyme
P57059	BXGT011210	Serine/threonine-protein kinase SIK1	150094	reviewed
P60022	BXGT011285	Beta-defensin 1	1672	reviewed
P62070	BXGT011404	Ras-related protein R-Ras2	22800	reviewed	Enzyme modulator
P78527	BXGT011846	DNA-dependent protein kinase catalytic subunit	5591	reviewed	Kinase
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
Q00059	BXGT012512	Transcription factor A, mitochondrial	7019	reviewed
Q00987	BXGT012559	E3 ubiquitin-protein ligase Mdm2	4193	reviewed	Nucleic acid binding
Q07820	BXGT012942	Induced myeloid leukemia cell differentiation protein Mcl-1	4170	reviewed	Signaling
Q08188	BXGT012965	Protein-glutamine gamma-glutamyltransferase E	7053	reviewed	Enzyme
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q99933	BXGT019976	BAG family molecular chaperone regulator 1	573	reviewed
Q9NP58	BXGT021143	ATP-binding cassette sub-family B member 6, mitochondrial	10058	reviewed	Transporter
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UBC3	BXGT021650	DNA (cytosine-5)-methyltransferase 3B	1789	reviewed
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q99435	BXGT025240	Protein kinase C-binding protein NELL2	4753	reviewed	Calcium-binding protein
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}