Showing entry for Free fatty acid receptor 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004180
Protein NameFree fatty acid receptor 2
Uniport IdO15552
GeneFFAR2
Gene Id2867
Domain7tm_1
Pfam PF00001  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04024 cAMP signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002752 cell surface pattern recognition receptor signaling pathway
Biological Process GO:0071398 cellular response to fatty acid
Biological Process GO:0045444 fat cell differentiation
Biological Process GO:0042593 glucose homeostasis
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0002232 leukocyte chemotaxis involved in inflammatory response
Biological Process GO:0019915 lipid storage
Biological Process GO:0002385 mucosal immune response
Biological Process GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus
Biological Process GO:0032722 positive regulation of chemokine production
Biological Process GO:0002720 positive regulation of cytokine production involved in immune response
Biological Process GO:0032757 positive regulation of interleukin-8 production
Biological Process GO:0002673 regulation of acute inflammatory response
Biological Process GO:0090276 regulation of peptide hormone secretion
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0008289 lipid binding
cellular component GO:0042995 cell projection
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-388396 GPCR downstream signalling
R-HSA-416476 G alpha (q) signalling events
R-HSA-444209 Free fatty acid receptors
R-HSA-500792 GPCR ligand binding
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001430 BXGD000054 Adenoma Neoplasms
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004623 BXGD000282 Bacterial Infections Infections
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009376 BXGD000603 Colonic Polyps Pathological Conditions, Signs and Symptoms
C0009806 BXGD000633 Constipation Pathological Conditions, Signs and Symptoms
C0011603 BXGD000734 Dermatitis Skin and Connective Tissue Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0018133 BXGD001176 Graft-vs-Host Disease Immune System Diseases
C0018553 BXGD001203 Hamartoma Syndrome, Multiple Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021831 BXGD001516 Intestinal Diseases Digestive System Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0032584 BXGD002363 polyps Pathological Conditions, Signs and Symptoms
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0035235 BXGD002519 Respiratory Syncytial Virus Infections Infections
C0042963 BXGD003018 Vomiting Pathological Conditions, Signs and Symptoms
C0232493 BXGD004550 Epigastric pain Pathological Conditions, Signs and Symptoms
C0271650 BXGD006227 Impaired glucose tolerance Nutritional and Metabolic Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C1112503 BXGD011674 Tubular adenoma of colon
C1269955 BXGD012005 Tumor Cell Invasion
C1290884 BXGD012198 Inflammatory disorder Pathological Conditions, Signs and Symptoms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1608408 BXGD013434 Malignant transformation
C2062441 BXGD016897 Influenza A
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C3875321 BXGD019874 Inflammatory dermatosis Skin and Connective Tissue Diseases
C4551463 BXGD023300 Colon adenoma Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0004269 Propanoic acid 74.08
BXGC0004277 Acetic acid 60.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein