Showing entry for Inflammatory disorder


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD012198
Disease NameInflammatory disorder
Disease CUI IdC1290884
MeSH Codes C23  
Disease Class NamePathological Conditions, Signs and Symptoms
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00141 BXGT003882 Serine/threonine-protein kinase Sgk1 6446 reviewed Kinase
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00244 BXGT003902 Copper transport protein ATOX1 475 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00482 BXGT003929 Nuclear receptor subfamily 5 group A member 2 2494 reviewed Nuclear receptor
O14684 BXGT004082 Prostaglandin E synthase 9536 reviewed
O14744 BXGT004089 Protein arginine N-methyltransferase 5 10419 reviewed Epigenetic regulator
O14920 BXGT004110 Inhibitor of nuclear factor kappa-B kinase subunit beta 3551 reviewed Kinase
O15054 BXGT004121 Lysine-specific demethylase 6B 23135 reviewed Epigenetic regulator
O15379 BXGT004159 Histone deacetylase 3 8841 reviewed Epigenetic regulator
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O15552 BXGT004180 Free fatty acid receptor 2 2867 reviewed G-protein coupled receptor
O15553 BXGT004181 Pyrin 4210 reviewed
O43318 BXGT004586 Mitogen-activated protein kinase kinase kinase 7 6885 reviewed Kinase
O43353 BXGT004589 Receptor-interacting serine/threonine-protein kinase 2 8767 reviewed Kinase
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O43612 BXGT004605 Orexin 3060 reviewed
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O95382 BXGT005376 Mitogen-activated protein kinase kinase kinase 6 9064 reviewed Kinase
O95407 BXGT005380 Tumor necrosis factor receptor superfamily member 6B 8771 reviewed
O95631 BXGT005387 Netrin-1 9423 reviewed Enzyme modulator
P00156 BXGT005469 Cytochrome b 4519 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01574 BXGT005768 Interferon beta 3456 reviewed
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02818 BXGT005969 Osteocalcin 632 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04062 BXGT006140 Lysosomal acid glucosylceramidase 2629 reviewed
P04070 BXGT006143 Vitamin K-dependent protein C 5624 reviewed Enzyme
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05109 BXGT006318 Protein S100-A8 6279 reviewed Calcium-binding protein
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P06756 BXGT006499 Integrin alpha-V 3685 reviewed
P06870 BXGT006518 Kallikrein-1 3816 reviewed Enzyme
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08246 BXGT006756 Neutrophil elastase 1991 reviewed Enzyme
P08648 BXGT006804 Integrin alpha-5 3678 reviewed
P08670 BXGT006810 Vimentin 7431 reviewed
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11169 BXGT007664 Solute carrier family 2, facilitated glucose transporter member 3 6515 reviewed Transporter
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P12314 BXGT007798 High affinity immunoglobulin gamma Fc receptor I 2209 reviewed Cell adhesion
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P13688 BXGT007943 Carcinoembryonic antigen-related cell adhesion molecule 1 634 reviewed
P14207 BXGT007993 Folate receptor beta 2350 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P15529 BXGT008134 Membrane cofactor protein 4179 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15941 BXGT008176 Mucin-1 4582 reviewed
P16109 BXGT008194 P-selectin 6403 reviewed
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P16473 BXGT008234 Thyrotropin receptor 7253 reviewed G-protein coupled receptor
P16581 BXGT008245 E-selectin 6401 reviewed
P17706 BXGT008330 Tyrosine-protein phosphatase non-receptor type 2 5771 reviewed
P17707 BXGT008331 S-adenosylmethionine decarboxylase proenzyme 262 reviewed Enzyme
P17861 BXGT008348 X-box-binding protein 1 7494 reviewed
P19113 BXGT008458 Histidine decarboxylase 3067 reviewed
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P21580 BXGT008666 Tumor necrosis factor alpha-induced protein 3 7128 reviewed Enzyme
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P22303 BXGT008751 Acetylcholinesterase 43 reviewed Enzyme
P22736 BXGT008800 Nuclear receptor subfamily 4 group A member 1 3164 reviewed Nuclear receptor
P24158 BXGT008951 Myeloblastin 5657 reviewed Enzyme
P25116 BXGT009025 Proteinase-activated receptor 1 2149 reviewed G-protein coupled receptor
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27338 BXGT009172 Amine oxidase [flavin-containing] B 4129 reviewed
P27815 BXGT009208 cAMP-specific 3',5'-cyclic phosphodiesterase 4A 5141 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29350 BXGT009335 Tyrosine-protein phosphatase non-receptor type 6 5777 reviewed
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P30086 BXGT009400 Phosphatidylethanolamine-binding protein 1 5037 reviewed Enzyme modulator
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P32119 BXGT009600 Peroxiredoxin-2 7001 reviewed Enzyme
P34972 BXGT009779 Cannabinoid receptor 2 1269 reviewed G-protein coupled receptor
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35398 BXGT009825 Nuclear receptor ROR-alpha 6095 reviewed Nuclear receptor
P35613 BXGT009856 Basigin 682 reviewed
P35754 BXGT009863 Glutaredoxin-1 2745 reviewed
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 89832 reviewed
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P40189 BXGT010164 Interleukin-6 receptor subunit beta 3572 reviewed Signaling
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41146 BXGT010226 Nociceptin receptor 4987 reviewed G-protein coupled receptor
P41279 BXGT010254 Mitogen-activated protein kinase kinase kinase 8 1326 reviewed Kinase
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43405 BXGT010386 Tyrosine-protein kinase SYK 6850 reviewed Kinase
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P47989 BXGT010602 Xanthine dehydrogenase/oxidase 7498 reviewed Enzyme
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49116 BXGT010678 Nuclear receptor subfamily 2 group C member 2 7182 reviewed Nuclear receptor
P49137 BXGT010680 MAP kinase-activated protein kinase 2 9261 reviewed Kinase
P49913 BXGT010761 Cathelicidin antimicrobial peptide 820 reviewed
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P50750 BXGT010818 Cyclin-dependent kinase 9 1025 reviewed Kinase
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P51686 BXGT010881 C-C chemokine receptor type 9 10803 reviewed G-protein coupled receptor
P55040 BXGT011099 GTP-binding protein GEM 2669 reviewed
P55087 BXGT011105 Aquaporin-4 361 reviewed Ion channel
P55265 BXGT011117 Double-stranded RNA-specific adenosine deaminase 103 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P61160 BXGT011365 Actin-related protein 2 10097 reviewed Cellular structure
P61769 BXGT011383 Beta-2-microglobulin 567 reviewed Immune response
P62491 BXGT011430 Ras-related protein Rab-11A 8766 reviewed
P62937 BXGT011471 Peptidyl-prolyl cis-trans isomerase A 5478 reviewed
P78417 BXGT011843 Glutathione S-transferase omega-1 9446 reviewed
P78556 BXGT011849 C-C motif chemokine 20 6364 reviewed Signaling
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P80511 BXGT011914 Protein S100-A12 6283 reviewed Calcium-binding protein
P81172 BXGT011935 Hepcidin 57817 reviewed
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q01831 BXGT012621 DNA repair protein complementing XP-C cells 7508 reviewed Nucleic acid binding
Q07108 BXGT012919 Early activation antigen CD69 969 reviewed
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q08499 BXGT012988 cAMP-specific 3',5'-cyclic phosphodiesterase 4D 5144 reviewed
Q09428 BXGT013036 ATP-binding cassette sub-family C member 8 6833 reviewed Transporter
Q12918 BXGT013280 Killer cell lectin-like receptor subfamily B member 1 3820 reviewed
Q13075 BXGT013308 Baculoviral IAP repeat-containing protein 1 4671 reviewed
Q13093 BXGT013310 Platelet-activating factor acetylhydrolase 7941 reviewed Enzyme
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13546 BXGT013372 Receptor-interacting serine/threonine-protein kinase 1 8737 reviewed Kinase
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14145 BXGT013448 Kelch-like ECH-associated protein 1 9817 reviewed
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q14697 BXGT013501 Neutral alpha-glucosidase AB 23193 reviewed Enzyme
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q15722 BXGT013590 Leukotriene B4 receptor 1 1241 reviewed G-protein coupled receptor
Q15746 BXGT013591 Myosin light chain kinase, smooth muscle 4638 reviewed Kinase
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16568 BXGT013640 Cocaine- and amphetamine-regulated transcript protein 9607 reviewed
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q53H47 BXGT015014 Histone-lysine N-methyltransferase SETMAR 6419 reviewed Epigenetic regulator
Q5D1E8 BXGT015318 Endoribonuclease ZC3H12A 80149 reviewed Nucleic acid binding
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 120892 reviewed Kinase
Q5VWK5 BXGT015891 Interleukin-23 receptor 149233 reviewed Signaling
Q676U5 BXGT016177 Autophagy-related protein 16-1 55054 reviewed
Q687X5 BXGT016184 Metalloreductase STEAP4 79689 reviewed
Q6N021 BXGT016378 Methylcytosine dioxygenase TET2 54790 reviewed
Q6P589 BXGT016452 Tumor necrosis factor alpha-induced protein 8-like protein 2 79626 reviewed
Q6ZQW0 BXGT016635 Indoleamine 2,3-dioxygenase 2 169355 reviewed
Q86U44 BXGT017610 N6-adenosine-methyltransferase catalytic subunit 56339 reviewed
Q86WV6 BXGT017626 Stimulator of interferon genes protein 340061 reviewed
Q8NBP7 BXGT018541 Proprotein convertase subtilisin/kexin type 9 255738 reviewed Enzyme
Q8WUI4 BXGT018992 Histone deacetylase 7 51564 reviewed Epigenetic regulator
Q92542 BXGT019354 Nicastrin 23385 reviewed
Q93009 BXGT019455 Ubiquitin carboxyl-terminal hydrolase 7 7874 reviewed Enzyme
Q93088 BXGT019458 Betaine--homocysteine S-methyltransferase 1 635 reviewed
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96J02 BXGT019679 E3 ubiquitin-protein ligase Itchy homolog 83737 reviewed Enzyme
Q96J66 BXGT019680 ATP-binding cassette sub-family C member 11 85320 reviewed Transporter
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96RI1 BXGT019727 Bile acid receptor 9971 reviewed Nuclear receptor
Q99623 BXGT019941 Prohibitin-2 11331 reviewed
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 4217 reviewed Kinase
Q99814 BXGT019965 Endothelial PAS domain-containing protein 1 2034 reviewed Transcription factor
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q9BUZ4 BXGT020139 TNF receptor-associated factor 4 9618 reviewed Signaling
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9HCN6 BXGT020535 Platelet glycoprotein VI 51206 reviewed Receptor
Q9NP99 BXGT021148 Triggering receptor expressed on myeloid cells 1 54210 reviewed
Q9NRA0 BXGT021183 Sphingosine kinase 2 56848 reviewed Kinase
Q9NYA1 BXGT021254 Sphingosine kinase 1 8877 reviewed Kinase
Q9NZ08 BXGT021266 Endoplasmic reticulum aminopeptidase 1 51752 reviewed Enzyme
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UBC3 BXGT021650 DNA (cytosine-5)-methyltransferase 3B 1789 reviewed
Q9UKU7 BXGT021749 Isobutyryl-CoA dehydrogenase, mitochondrial 27034 reviewed Enzyme
Q9UNN8 BXGT021791 Endothelial protein C receptor 10544 reviewed Enzyme modulator
Q9Y239 BXGT022213 Nucleotide-binding oligomerization domain-containing protein 1 10392 reviewed Enzyme
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y3Z3 BXGT022268 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 25939 reviewed
Q9Y572 BXGT022289 Receptor-interacting serine/threonine-protein kinase 3 11035 reviewed Kinase
Q9Y6E0 BXGT022327 Serine/threonine-protein kinase 24 8428 reviewed Kinase
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
Q01543 BXGT023137 Friend leukemia integration 1 transcription factor 2313 reviewed Transcription factor
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q96QC4 BXGT023878 MHC class I polypeptide-related sequence A 100507436 unreviewed
P20809 BXGT025043 Interleukin-11 3589 reviewed
Q7L804 BXGT025539 Rab11 family-interacting protein 2 22841 reviewed
Q969H8 BXGT025606 Myeloid-derived growth factor 56005 reviewed
Q9UKU9 BXGT025985 Angiopoietin-related protein 2 23452 reviewed Signaling
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
Q96K76 BXGT026122 Ubiquitin carboxyl-terminal hydrolase 47 55031 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease