Showing entry for SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004865
Protein NameSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5
Uniport IdO60264
GeneSMARCA5
Gene Id8467
DomainDBINO; HAND; Helicase_C; SLIDE; SNF2_N
Pfam PF13892   PF09110   PF00271   PF09111   PF00176  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0043044 ATP-dependent chromatin remodeling
Biological Process GO:1990830 cellular response to leukemia inhibitory factor
Biological Process GO:0034080 CENP-A containing nucleosome assembly
Biological Process GO:0006338 chromatin remodeling
Biological Process GO:0006352 DNA-templated transcription, initiation
Biological Process GO:0006334 nucleosome assembly
Biological Process GO:0016584 nucleosome positioning
Biological Process GO:0045815 positive regulation of gene expression, epigenetic
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0000183 rDNA heterochromatin assembly
Biological Process GO:0006357 regulation of transcription by RNA polymerase II
molecular function GO:0016887 ATPase activity
molecular function GO:0005524 ATP binding
molecular function GO:0003677 DNA binding
molecular function GO:0008094 DNA-dependent ATPase activity
molecular function GO:0004386 helicase activity
molecular function GO:0031491 nucleosome binding
cellular component GO:0005677 chromatin silencing complex
cellular component GO:0000793 condensed chromosome
cellular component GO:0001650 fibrillar center
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0016589 NURF complex
cellular component GO:0031213 RSF complex
Reactome
Pathway Id Pathway Name
R-HSA-1640170 Cell Cycle
R-HSA-212165 Epigenetic regulation of gene expression
R-HSA-212165 Epigenetic regulation of gene expression
R-HSA-427413 NoRC negatively regulates rRNA expression
R-HSA-5250913 Positive epigenetic regulation of rRNA expression
R-HSA-5250924 B-WICH complex positively regulates rRNA expression
R-HSA-5250941 Negative epigenetic regulation of rRNA expression
R-HSA-5693532 DNA Double-Strand Break Repair
R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
R-HSA-5693606 DNA Double Strand Break Response
R-HSA-606279 Deposition of new CENPA-containing nucleosomes at the centromere
R-HSA-73886 Chromosome Maintenance
R-HSA-73894 DNA Repair
R-HSA-74160 Gene expression (Transcription)
R-HSA-74160 Gene expression (Transcription)
R-HSA-774815 Nucleosome assembly
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0002878 BXGD000137 Anemia, Hemolytic Hemic and Lymphatic Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0017638 BXGD001132 Glioma Neoplasms
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0019159 BXGD001294 Hepatitis A Digestive System Diseases; Infections
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026936 BXGD001950 Mycoplasma Infections Infections
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0085669 BXGD003233 Acute leukemia Pathological Conditions, Signs and Symptoms; Neoplasms
C0153690 BXGD003684 Secondary malignant neoplasm of bone Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0206663 BXGD004225 Neuroectodermal Tumor, Primitive Neoplasms
C0276041 BXGD006397 Chronic respiratory disease due to Mycoplasma gallisepticum Infections
C0279980 BXGD006701 Extra-osseous Ewing's sarcoma Neoplasms
C0349588 BXGD007933 Short stature
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0553580 BXGD009399 Ewings sarcoma Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0858355 BXGD011177 Addicted to cocaine
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1834673 BXGD013986 Facioscapulohumeral muscular dystrophy 1a Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0005620 beta-D-Glucopyranose 180.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein