adisease

Showing entry for Cirrhosis

General Disease Information
BXGD Id	BXGD013475
Disease Name	Cirrhosis
Disease CUI Id	C1623038
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O00482	BXGT003929	Nuclear receptor subfamily 5 group A member 2	2494	reviewed	Nuclear receptor
O00602	BXGT003940	Ficolin-1	2219	reviewed	Signaling
O14733	BXGT004087	Dual specificity mitogen-activated protein kinase kinase 7	5609	reviewed	Kinase
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O14786	BXGT004099	Neuropilin-1	8829	reviewed
O15075	BXGT004124	Serine/threonine-protein kinase DCLK1	9201	reviewed	Kinase
O15120	BXGT004129	1-acyl-sn-glycerol-3-phosphate acyltransferase beta	10555	reviewed
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O15169	BXGT004134	Axin-1	8312	reviewed
O15350	BXGT004154	Tumor protein p73	7161	reviewed	Transcription factor
O15392	BXGT004162	Baculoviral IAP repeat-containing protein 5	332	reviewed	Enzyme modulator
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O43278	BXGT004581	Kunitz-type protease inhibitor 1	6692	reviewed
O43597	BXGT004602	Protein sprouty homolog 2	10253	reviewed	Signaling
O60218	BXGT004858	Aldo-keto reductase family 1 member B10	57016	reviewed	Enzyme
O60264	BXGT004865	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5	8467	reviewed	Enzyme
O60462	BXGT004876	Neuropilin-2	8828	reviewed
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O75015	BXGT005095	Low affinity immunoglobulin gamma Fc region receptor III-B	2215	reviewed	Cell adhesion
O75367	BXGT005117	Core histone macro-H2A.1	9555	reviewed	Nucleic acid binding
O75469	BXGT005128	Nuclear receptor subfamily 1 group I member 2	8856	reviewed	Nuclear receptor
O75496	BXGT005132	Geminin	51053	reviewed
O94760	BXGT005328	N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	23576	reviewed	Enzyme
O94925	BXGT005342	Glutaminase kidney isoform, mitochondrial	2744	reviewed	Enzyme
O95150	BXGT005351	Tumor necrosis factor ligand superfamily member 15	9966	reviewed	Signaling
O95342	BXGT005373	Bile salt export pump	8647	reviewed	Transporter
O95622	BXGT005386	Adenylate cyclase type 5	111	reviewed
O95749	BXGT005394	Geranylgeranyl pyrophosphate synthase	9453	reviewed
O95750	BXGT005395	Fibroblast growth factor 19	9965	reviewed	Signaling
P00325	BXGT005498	Alcohol dehydrogenase 1B	125	reviewed	Enzyme
P00326	BXGT005499	Alcohol dehydrogenase 1C	126	reviewed	Enzyme
P00450	BXGT005544	Ceruloplasmin	1356	reviewed	Enzyme
P00451	BXGT005545	Coagulation factor VIII	2157	reviewed	Enzyme
P00480	BXGT005551	Ornithine carbamoyltransferase, mitochondrial	5009	reviewed
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P00749	BXGT005641	Urokinase-type plasminogen activator	5328	reviewed	Enzyme
P00751	BXGT005643	Complement factor B	629	reviewed
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P00966	BXGT005707	Argininosuccinate synthase	445	reviewed	Enzyme
P01008	BXGT005713	Antithrombin-III	462	reviewed	Enzyme modulator
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01034	BXGT005721	Cystatin-C	1471	reviewed
P01042	BXGT005722	Kininogen-1	3827	reviewed	Enzyme modulator
P01100	BXGT005727	Proto-oncogene c-Fos	2353	reviewed	Transcription factor
P01106	BXGT005730	Myc proto-oncogene protein	4609	reviewed	Transcription factor
P01130	BXGT005735	Low-density lipoprotein receptor	3949	reviewed
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01148	BXGT005739	Progonadoliberin-1	2796	reviewed
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P01275	BXGT005747	Glucagon	2641	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01591	BXGT005774	Immunoglobulin J chain	3512	reviewed
P01833	BXGT005788	Polymeric immunoglobulin receptor	5284	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02452	BXGT005878	Collagen alpha-1(I) chain	1277	reviewed
P02461	BXGT005880	Collagen alpha-1(III) chain	1281	reviewed
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02708	BXGT005927	Acetylcholine receptor subunit alpha	1134	reviewed	Ion channel
P02730	BXGT005935	Band 3 anion transport protein	6521	reviewed	Transporter
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P02753	BXGT005945	Retinol-binding protein 4	5950	reviewed	Transporter
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02787	BXGT005962	Serotransferrin	7018	reviewed	Enzyme
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04004	BXGT006125	Vitronectin	7448	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04054	BXGT006136	Phospholipase A2	5319	reviewed	Enzyme
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P04070	BXGT006143	Vitamin K-dependent protein C	5624	reviewed	Enzyme
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04275	BXGT006180	von Willebrand factor	7450	reviewed	Enzyme modulator
P04278	BXGT006182	Sex hormone-binding globulin	6462	reviewed
P04406	BXGT006207	Glyceraldehyde-3-phosphate dehydrogenase	2597	reviewed	Enzyme
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P04839	BXGT006273	Cytochrome b-245 heavy chain	1536	reviewed	Ion channel
P05062	BXGT006305	Fructose-bisphosphate aldolase B	229	reviewed
P05091	BXGT006312	Aldehyde dehydrogenase, mitochondrial	217	reviewed	Enzyme
P05093	BXGT006313	Steroid 17-alpha-hydroxylase/17,20 lyase	1586	reviewed
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05155	BXGT006328	Plasma protease C1 inhibitor	710	reviewed	Enzyme modulator
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05177	BXGT006336	Cytochrome P450 1A2	1544	reviewed	Enzyme
P05181	BXGT006337	Cytochrome P450 2E1	1571	reviewed
P05187	BXGT006339	Alkaline phosphatase, placental type	250	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05556	BXGT006368	Integrin beta-1	3688	reviewed	Receptor
P05787	BXGT006385	Keratin, type II cytoskeletal 8	3856	reviewed
P06276	BXGT006430	Cholinesterase	590	reviewed
P06493	BXGT006445	Cyclin-dependent kinase 1	983	reviewed	Kinase
P06702	BXGT006476	Protein S100-A9	6280	reviewed	Calcium-binding protein
P06731	BXGT006488	Carcinoembryonic antigen-related cell adhesion molecule 5	1048	reviewed
P06733	BXGT006490	Alpha-enolase	2023	reviewed	Enzyme
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P06870	BXGT006518	Kallikrein-1	3816	reviewed	Enzyme
P07202	BXGT006565	Thyroid peroxidase	7173	reviewed	Enzyme
P07203	BXGT006566	Glutathione peroxidase 1	2876	reviewed	Enzyme
P07204	BXGT006567	Thrombomodulin	7056	reviewed
P07225	BXGT006572	Vitamin K-dependent protein S	5627	reviewed
P07355	BXGT006609	Annexin A2	302	reviewed
P07550	BXGT006636	Beta-2 adrenergic receptor	154	reviewed	G-protein coupled receptor
P07686	BXGT006657	Beta-hexosaminidase subunit beta	3074	reviewed	Enzyme
P07902	BXGT006697	Galactose-1-phosphate uridylyltransferase	2592	reviewed	Enzyme
P07996	BXGT006710	Thrombospondin-1	7057	reviewed
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P08138	BXGT006729	Tumor necrosis factor receptor superfamily member 16	4804	reviewed	Receptor
P08151	BXGT006731	Zinc finger protein GLI1	2735	reviewed
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08235	BXGT006751	Mineralocorticoid receptor	4306	reviewed	Nuclear receptor
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08254	BXGT006758	Stromelysin-1	4314	reviewed	Enzyme
P08263	BXGT006759	Glutathione S-transferase A1	2938	reviewed
P08397	BXGT006768	Porphobilinogen deaminase	3145	reviewed	Enzyme
P08514	BXGT006781	Integrin alpha-IIb	3674	reviewed
P08581	BXGT006794	Hepatocyte growth factor receptor	4233	reviewed	Kinase
P08637	BXGT006802	Low affinity immunoglobulin gamma Fc region receptor III-A	2214	reviewed	Cell adhesion
P08670	BXGT006810	Vimentin	7431	reviewed
P08684	BXGT006812	Cytochrome P450 3A4	1576	reviewed	Enzyme
P08758	BXGT006821	Annexin A5	308	reviewed
P08833	BXGT006827	Insulin-like growth factor-binding protein 1	3484	reviewed	Enzyme modulator
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P08913	BXGT006841	Alpha-2A adrenergic receptor	150	reviewed	G-protein coupled receptor
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09237	BXGT006874	Matrilysin	4316	reviewed	Enzyme
P09455	BXGT006890	Retinol-binding protein 1	5947	reviewed
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P09917	BXGT006941	Arachidonate 5-lipoxygenase	240	reviewed	Enzyme
P10070	BXGT007534	Zinc finger protein GLI2	2736	reviewed
P10109	BXGT007538	Adrenodoxin, mitochondrial	2230	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10635	BXGT007595	Cytochrome P450 2D6	1565	reviewed
P10646	BXGT007598	Tissue factor pathway inhibitor	7035	reviewed	Enzyme modulator
P10826	BXGT007622	Retinoic acid receptor beta	5915	reviewed	Nuclear receptor
P10909	BXGT007630	Clusterin	1191	reviewed
P11021	BXGT007644	Endoplasmic reticulum chaperone BiP	3309	reviewed
P11215	BXGT007672	Integrin alpha-M	3684	reviewed
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P11509	BXGT007716	Cytochrome P450 2A6	1548	reviewed
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P11717	BXGT007740	Cation-independent mannose-6-phosphate receptor	3482	reviewed	Receptor
P12004	BXGT007766	Proliferating cell nuclear antigen	5111	reviewed	Nucleic acid binding
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P12830	BXGT007852	Cadherin-1	999	reviewed
P12931	BXGT007859	Proto-oncogene tyrosine-protein kinase Src	6714	reviewed	Kinase
P13236	BXGT007891	C-C motif chemokine 4	6351	reviewed
P13489	BXGT007913	Ribonuclease inhibitor	6050	reviewed	Transcription factor
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P13945	BXGT007972	Beta-3 adrenergic receptor	155	reviewed	G-protein coupled receptor
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14550	BXGT008019	Aldo-keto reductase family 1 member A1	10327	reviewed	Enzyme
P14555	BXGT008020	Phospholipase A2, membrane associated	5320	reviewed	Enzyme
P14616	BXGT008026	Insulin receptor-related protein	3645	reviewed	Kinase
P14621	BXGT008028	Acylphosphatase-2	98	reviewed	Enzyme
P14625	BXGT008029	Endoplasmin	7184	reviewed	Chaperone
P14672	BXGT008037	Solute carrier family 2, facilitated glucose transporter member 4	6517	reviewed	Transporter
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14902	BXGT008065	Indoleamine 2,3-dioxygenase 1	3620	reviewed
P15086	BXGT008078	Carboxypeptidase B	1360	reviewed	Enzyme
P15090	BXGT008079	Fatty acid-binding protein, adipocyte	2167	reviewed
P15104	BXGT008081	Glutamine synthetase	2752	reviewed	Enzyme
P15559	BXGT008139	NAD(P)H dehydrogenase [quinone] 1	1728	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15735	BXGT008151	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	5261	reviewed	Kinase
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P15907	BXGT008168	Beta-galactoside alpha-2,6-sialyltransferase 1	6480	reviewed
P16066	BXGT008185	Atrial natriuretic peptide receptor 1	4881	reviewed	Kinase
P16070	BXGT008186	CD44 antigen	960	reviewed
P16109	BXGT008194	P-selectin	6403	reviewed
P16234	BXGT008209	Platelet-derived growth factor receptor alpha	5156	reviewed	Kinase
P16278	BXGT008213	Beta-galactosidase	2720	reviewed	Enzyme
P16442	BXGT008227	Histo-blood group ABO system transferase	28	reviewed	Enzyme
P16455	BXGT008229	Methylated-DNA--protein-cysteine methyltransferase	4255	reviewed
P16930	BXGT008272	Fumarylacetoacetase	2184	reviewed
P17405	BXGT008304	Sphingomyelin phosphodiesterase	6609	reviewed	Enzyme
P17844	BXGT008346	Probable ATP-dependent RNA helicase DDX5	1655	reviewed
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P17936	BXGT008357	Insulin-like growth factor-binding protein 3	3486	reviewed	Enzyme modulator
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	2321	reviewed	Kinase
P18075	BXGT008375	Bone morphogenetic protein 7	655	reviewed	Signaling
P18825	BXGT008426	Alpha-2C adrenergic receptor	152	reviewed	G-protein coupled receptor
P18887	BXGT008437	DNA repair protein XRCC1	7515	reviewed
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19440	BXGT008481	Glutathione hydrolase 1 proenzyme	2678	reviewed	Enzyme
P19883	BXGT008528	Follistatin	10468	reviewed	Enzyme modulator
P19971	BXGT008537	Thymidine phosphorylase	1890	reviewed	Enzyme
P20813	BXGT008603	Cytochrome P450 2B6	1555	reviewed
P20933	BXGT008618	N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	175	reviewed	Enzyme
P21439	BXGT008649	Phosphatidylcholine translocator ABCB4	5244	reviewed	Transporter
P21580	BXGT008666	Tumor necrosis factor alpha-induced protein 3	7128	reviewed	Enzyme
P21589	BXGT008669	5'-nucleotidase	4907	reviewed	Enzyme
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P22087	BXGT008729	rRNA 2'-O-methyltransferase fibrillarin	2091	reviewed	Enzyme
P22303	BXGT008751	Acetylcholinesterase	43	reviewed	Enzyme
P22830	BXGT008809	Ferrochelatase, mitochondrial	2235	reviewed	Enzyme
P22894	BXGT008815	Neutrophil collagenase	4317	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P24530	BXGT008975	Endothelin receptor type B	1910	reviewed	G-protein coupled receptor
P25101	BXGT009018	Endothelin-1 receptor	1909	reviewed	G-protein coupled receptor
P26358	BXGT009104	DNA (cytosine-5)-methyltransferase 1	1786	reviewed	Epigenetic regulator
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	328	reviewed
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	3356	reviewed	G-protein coupled receptor
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28676	BXGT009284	Grancalcin	25801	reviewed
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P29508	BXGT009358	Serpin B3	6317	reviewed	Enzyme modulator
P30101	BXGT009402	Protein disulfide-isomerase A3	2923	reviewed
P30279	BXGT009415	G1/S-specific cyclin-D2	894	reviewed	Enzyme modulator
P30518	BXGT009428	Vasopressin V2 receptor	554	reviewed	G-protein coupled receptor
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P31153	BXGT009512	S-adenosylmethionine synthase isoform type-2	4144	reviewed	Enzyme
P31350	BXGT009526	Ribonucleoside-diphosphate reductase subunit M2	6241	reviewed	Enzyme
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P31997	BXGT009593	Carcinoembryonic antigen-related cell adhesion molecule 8	1088	reviewed
P32241	BXGT009613	Vasoactive intestinal polypeptide receptor 1	7433	reviewed	G-protein coupled receptor
P33261	BXGT009707	Cytochrome P450 2C19	1557	reviewed
P34949	BXGT009775	Mannose-6-phosphate isomerase	4351	reviewed	Enzyme
P34969	BXGT009777	5-hydroxytryptamine receptor 7	3363	reviewed	G-protein coupled receptor
P34972	BXGT009779	Cannabinoid receptor 2	1269	reviewed	G-protein coupled receptor
P35052	BXGT009788	Glypican-1	2817	reviewed
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35557	BXGT009846	Glucokinase	2645	reviewed	Kinase
P35613	BXGT009856	Basigin	682	reviewed
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P36955	BXGT009946	Pigment epithelium-derived factor	5176	reviewed	Enzyme modulator
P36969	BXGT009949	Phospholipid hydroperoxide glutathione peroxidase	2879	reviewed	Enzyme
P37023	BXGT009953	Serine/threonine-protein kinase receptor R3	94	reviewed	Kinase
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P38571	BXGT010054	Lysosomal acid lipase/cholesteryl ester hydrolase	3988	reviewed	Enzyme
P38936	BXGT010074	Cyclin-dependent kinase inhibitor 1	1026	reviewed
P39060	BXGT010088	Collagen alpha-1(XVIII) chain	80781	reviewed
P40225	BXGT010168	Thrombopoietin	7066	reviewed
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P41143	BXGT010223	Delta-type opioid receptor	4985	reviewed	G-protein coupled receptor
P41180	BXGT010230	Extracellular calcium-sensing receptor	846	reviewed	G-protein coupled receptor
P41222	BXGT010237	Prostaglandin-H2 D-isomerase	5730	reviewed	Enzyme
P41235	BXGT010241	Hepatocyte nuclear factor 4-alpha	3172	reviewed	Nuclear receptor
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	6772	reviewed	Nucleic acid binding
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43220	BXGT010367	Glucagon-like peptide 1 receptor	2740	reviewed	G-protein coupled receptor
P43405	BXGT010386	Tyrosine-protein kinase SYK	6850	reviewed	Kinase
P45452	BXGT010462	Collagenase 3	4322	reviewed	Enzyme
P46019	BXGT010498	Phosphorylase b kinase regulatory subunit alpha, liver isoform	5256	reviewed	Kinase
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P46940	BXGT010556	Ras GTPase-activating-like protein IQGAP1	8826	reviewed	Enzyme modulator
P47712	BXGT010577	Cytosolic phospholipase A2	5321	reviewed	Enzyme
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P48544	BXGT010641	G protein-activated inward rectifier potassium channel 4	3762	reviewed	Ion channel
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49281	BXGT010689	Natural resistance-associated macrophage protein 2	4891	reviewed	Transporter
P49747	BXGT010732	Cartilage oligomeric matrix protein	1311	reviewed
P49763	BXGT010737	Placenta growth factor	5228	reviewed	Signaling
P49767	BXGT010739	Vascular endothelial growth factor C	7424	reviewed	Signaling
P49789	BXGT010742	Bis(5'-adenosyl)-triphosphatase	2272	reviewed
P49908	BXGT010760	Selenoprotein P	6414	reviewed	Extracellular structure
P49917	BXGT010765	DNA ligase 4	3981	reviewed
P50281	BXGT010788	Matrix metalloproteinase-14	4323	reviewed	Enzyme
P50591	BXGT010814	Tumor necrosis factor ligand superfamily member 10	8743	reviewed	Signaling
P51531	BXGT010851	Probable global transcription activator SNF2L2	6595	reviewed	Epigenetic regulator
P51532	BXGT010852	Transcription activator BRG1	6597	reviewed	Epigenetic regulator
P51580	BXGT010864	Thiopurine S-methyltransferase	7172	reviewed
P51857	BXGT010899	Aldo-keto reductase family 1 member D1	6718	reviewed	Enzyme
P51884	BXGT010903	Lumican	4060	reviewed
P52790	BXGT010955	Hexokinase-3	3101	reviewed	Kinase
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P54802	BXGT011081	Alpha-N-acetylglucosaminidase	4669	reviewed
P54868	BXGT011090	Hydroxymethylglutaryl-CoA synthase, mitochondrial	3158	reviewed
P55040	BXGT011099	GTP-binding protein GEM	2669	reviewed
P55157	BXGT011108	Microsomal triglyceride transfer protein large subunit	4547	reviewed	Transporter
P55789	BXGT011126	FAD-linked sulfhydryl oxidase ALR	2671	reviewed	Enzyme
P60568	BXGT011315	Interleukin-2	3558	reviewed
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P61024	BXGT011350	Cyclin-dependent kinases regulatory subunit 1	1163	reviewed	Enzyme modulator
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P61086	BXGT011357	Ubiquitin-conjugating enzyme E2 K	3093	reviewed
P62993	BXGT011480	Growth factor receptor-bound protein 2	2885	reviewed
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
P63104	BXGT011499	14-3-3 protein zeta/delta	7534	reviewed	Chaperone
P68871	BXGT011615	Hemoglobin subunit beta	3043	reviewed
P78396	BXGT011842	Cyclin-A1	8900	reviewed	Enzyme modulator
P78417	BXGT011843	Glutathione S-transferase omega-1	9446	reviewed
P78504	BXGT011844	Protein jagged-1	182	reviewed
P78536	BXGT011847	Disintegrin and metalloproteinase domain-containing protein 17	6868	reviewed
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
P81172	BXGT011935	Hepcidin	57817	reviewed
P98160	BXGT012228	Basement membrane-specific heparan sulfate proteoglycan core protein	3339	reviewed	Enzyme modulator
Q00059	BXGT012512	Transcription factor A, mitochondrial	7019	reviewed
Q00266	BXGT012515	S-adenosylmethionine synthase isoform type-1	4143	reviewed	Enzyme
Q00535	BXGT012534	Cyclin-dependent-like kinase 5	1020	reviewed	Kinase
Q00610	BXGT012539	Clathrin heavy chain 1	1213	reviewed	Transporter
Q00987	BXGT012559	E3 ubiquitin-protein ligase Mdm2	4193	reviewed	Nucleic acid binding
Q01082	BXGT012567	Spectrin beta chain, non-erythrocytic 1	6711	reviewed
Q01094	BXGT012568	Transcription factor E2F1	1869	reviewed	Nucleic acid binding
Q01118	BXGT012570	Sodium channel protein type 7 subunit alpha	6332	reviewed	Ion channel
Q02083	BXGT012633	N-acylethanolamine-hydrolyzing acid amidase	27163	reviewed	Enzyme
Q02763	BXGT012667	Angiopoietin-1 receptor	7010	reviewed	Kinase
Q04446	BXGT012764	1,4-alpha-glucan-branching enzyme	2632	reviewed	Enzyme
Q04609	BXGT012768	Glutamate carboxypeptidase 2	2346	reviewed	Enzyme
Q04756	BXGT012780	Hepatocyte growth factor activator	3083	reviewed	Enzyme
Q04760	BXGT012782	Lactoylglutathione lyase	2739	reviewed
Q06278	BXGT012869	Aldehyde oxidase	316	reviewed	Enzyme
Q06828	BXGT012893	Fibromodulin	2331	reviewed
Q08345	BXGT012982	Epithelial discoidin domain-containing receptor 1	780	reviewed	Kinase
Q09472	BXGT013038	Histone acetyltransferase p300	2033	reviewed
Q12866	BXGT013273	Tyrosine-protein kinase Mer	10461	reviewed	Kinase
Q12879	BXGT013275	Glutamate receptor ionotropic, NMDA 2A	2903	reviewed	Ion channel
Q13224	BXGT013328	Glutamate receptor ionotropic, NMDA 2B	2904	reviewed	Ion channel
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13427	BXGT013354	Peptidyl-prolyl cis-trans isomerase G	9360	reviewed
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q13501	BXGT013365	Sequestosome-1	8878	reviewed
Q13547	BXGT013373	Histone deacetylase 1	3065	reviewed	Epigenetic regulator
Q14108	BXGT013440	Lysosome membrane protein 2	950	reviewed	Receptor
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14457	BXGT013472	Beclin-1	8678	reviewed	Enzyme modulator
Q14653	BXGT013494	Interferon regulatory factor 3	3661	reviewed	Transcription factor
Q14749	BXGT013503	Glycine N-methyltransferase	27232	reviewed
Q14973	BXGT013515	Sodium/bile acid cotransporter	6554	reviewed	Transporter
Q14995	BXGT013520	Nuclear receptor subfamily 1 group D member 2	9975	reviewed	Nuclear receptor
Q15389	BXGT013564	Angiopoietin-1	284	reviewed	Signaling
Q15485	BXGT013574	Ficolin-2	2220	reviewed	Signaling
Q15582	BXGT013581	Transforming growth factor-beta-induced protein ig-h3	7045	reviewed	Signaling
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16549	BXGT013637	Proprotein convertase subtilisin/kexin type 7	9159	reviewed
Q16637	BXGT013646	Survival motor neuron protein	6607	reviewed	Epigenetic regulator
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16698	BXGT013659	2,4-dienoyl-CoA reductase, mitochondrial	1666	reviewed	Enzyme
Q16790	BXGT013670	Carbonic anhydrase 9	768	reviewed
Q16853	BXGT013683	Membrane primary amine oxidase	8639	reviewed
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q53TN4	BXGT015019	Cytochrome b reductase 1	79901	reviewed	Enzyme
Q5T6L4	BXGT015848	Argininosuccinate synthase 1 isoform 1	445	unreviewed
Q658P3	BXGT016142	Metalloreductase STEAP3	55240	reviewed
Q676U5	BXGT016177	Autophagy-related protein 16-1	55054	reviewed
Q6ZQY3	BXGT016636	Acidic amino acid decarboxylase GADL1	339896	reviewed
Q6ZVN8	BXGT016641	Hemojuvelin	148738	reviewed
Q76LX8	BXGT016870	A disintegrin and metalloproteinase with thrombospondin motifs 13	11093	reviewed	Enzyme
Q7L266	BXGT016993	Isoaspartyl peptidase/L-asparaginase	80150	reviewed	Enzyme
Q7LG56	BXGT016999	Ribonucleoside-diphosphate reductase subunit M2 B	50484	reviewed	Enzyme
Q7Z494	BXGT017254	Nephrocystin-3	27031	reviewed
Q86TM3	BXGT017607	Probable ATP-dependent RNA helicase DDX53	168400	reviewed
Q86V24	BXGT017615	Adiponectin receptor protein 2	79602	reviewed	Receptor
Q8IXJ6	BXGT018362	NAD-dependent protein deacetylase sirtuin-2	22933	reviewed	Epigenetic regulator
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q8TD30	BXGT018805	Alanine aminotransferase 2	84706	reviewed	Enzyme
Q8TDQ0	BXGT018810	Hepatitis A virus cellular receptor 2	84868	reviewed
Q8WXD0	BXGT019009	Relaxin receptor 2	122042	reviewed	G-protein coupled receptor
Q8WY64	BXGT019017	E3 ubiquitin-protein ligase MYLIP	29116	reviewed
Q92887	BXGT019389	Canalicular multispecific organic anion transporter 1	1244	reviewed	Transporter
Q92905	BXGT019393	COP9 signalosome complex subunit 5	10987	reviewed	Enzyme
Q969Q1	BXGT019610	E3 ubiquitin-protein ligase TRIM63	84676	reviewed
Q96A70	BXGT019615	Antizyme inhibitor 2	113451	reviewed	Enzyme
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96GD4	BXGT019667	Aurora kinase B	9212	reviewed	Kinase
Q96J02	BXGT019679	E3 ubiquitin-protein ligase Itchy homolog	83737	reviewed	Enzyme
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96QV1	BXGT019722	Hedgehog-interacting protein	64399	reviewed
Q96RI1	BXGT019727	Bile acid receptor	9971	reviewed	Nuclear receptor
Q99418	BXGT019920	Cytohesin-2	9266	reviewed
Q99873	BXGT019972	Protein arginine N-methyltransferase 1	3276	reviewed	Epigenetic regulator
Q9BQ65	BXGT020107	U6 snRNA phosphodiesterase	79650	reviewed
Q9BY32	BXGT020179	Inosine triphosphate pyrophosphatase	3704	reviewed	Enzyme
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9BZZ2	BXGT020205	Sialoadhesin	6614	reviewed
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9H0A0	BXGT020434	RNA cytidine acetyltransferase	55226	reviewed
Q9H9B1	BXGT020501	Histone-lysine N-methyltransferase EHMT1	79813	reviewed	Epigenetic regulator
Q9HAW7	BXGT020508	UDP-glucuronosyltransferase 1-7	54577	reviewed
Q9HBE5	BXGT020518	Interleukin-21 receptor	50615	reviewed	Receptor
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9HC97	BXGT020527	G-protein coupled receptor 35	2859	reviewed	G-protein coupled receptor
Q9HCN6	BXGT020535	Platelet glycoprotein VI	51206	reviewed	Receptor
Q9NP58	BXGT021143	ATP-binding cassette sub-family B member 6, mitochondrial	10058	reviewed	Transporter
Q9NPH5	BXGT021159	NADPH oxidase 4	50507	reviewed	Enzyme
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NRF2	BXGT021185	SH2B adapter protein 1	25970	reviewed
Q9NRR6	BXGT021193	Phosphatidylinositol polyphosphate 5-phosphatase type IV	56623	reviewed
Q9NTG7	BXGT021211	NAD-dependent protein deacetylase sirtuin-3, mitochondrial	23410	reviewed	Epigenetic regulator
Q9NV35	BXGT021222	Nucleotide triphosphate diphosphatase NUDT15	55270	reviewed
Q9NWX6	BXGT021238	Probable tRNA(His) guanylyltransferase	54974	reviewed
Q9NYA1	BXGT021254	Sphingosine kinase 1	8877	reviewed	Kinase
Q9NYK1	BXGT021258	Toll-like receptor 7	51284	reviewed
Q9UBC3	BXGT021650	DNA (cytosine-5)-methyltransferase 3B	1789	reviewed
Q9UJS0	BXGT021727	Calcium-binding mitochondrial carrier protein Aralar2	10165	reviewed	Transporter
Q9UK80	BXGT021739	Ubiquitin carboxyl-terminal hydrolase 21	27005	reviewed	Enzyme
Q9UM47	BXGT021772	Neurogenic locus notch homolog protein 3	4854	reviewed
Q9Y275	BXGT022223	Tumor necrosis factor ligand superfamily member 13B	10673	reviewed
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y3B4	BXGT022255	Splicing factor 3B subunit 6	51639	reviewed
Q9Y5K2	BXGT022293	Kallikrein-4	9622	reviewed	Enzyme
Q9Y5L0	BXGT022296	Transportin-3	23534	reviewed	Transporter
Q9Y5S1	BXGT022300	Transient receptor potential cation channel subfamily V member 2	51393	reviewed	Ion channel
Q9Y5S8	BXGT022302	NADPH oxidase 1	27035	reviewed
Q9Y5W5	BXGT022303	Wnt inhibitory factor 1	11197	reviewed	Calcium-binding protein
Q9Y5Y6	BXGT022308	Suppressor of tumorigenicity 14 protein	6768	reviewed	Enzyme
Q9Y6K1	BXGT022331	DNA (cytosine-5)-methyltransferase 3A	1788	reviewed
Q9Y6X2	BXGT022343	E3 SUMO-protein ligase PIAS3	10401	reviewed
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
P35232	BXGT022663	Prohibitin	5245	reviewed
Q9Y6T7	BXGT022665	Diacylglycerol kinase beta	1607	reviewed	Enzyme
P52429	BXGT022667	Diacylglycerol kinase epsilon	8526	reviewed	Enzyme
P24462	BXGT022674	Cytochrome P450 3A7	1551	reviewed
P43146	BXGT022852	Netrin receptor DCC	1630	reviewed
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
P16284	BXGT022972	Platelet endothelial cell adhesion molecule	5175	reviewed	Cell adhesion
Q9UK05	BXGT023094	Growth/differentiation factor 2	2658	reviewed	Signaling
O14793	BXGT023280	Growth/differentiation factor 8	2660	reviewed	Signaling
O60502	BXGT023392	Protein O-GlcNAcase	10724	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P35670	BXGT023695	Copper-transporting ATPase 2	540	reviewed	Transporter
Q9HAU4	BXGT024040	E3 ubiquitin-protein ligase SMURF2	64750	reviewed	Enzyme
O60232	BXGT024169	Protein ZNRD2	10534	reviewed
O95399	BXGT024237	Urotensin-2	10911	reviewed
Q9UKP6	BXGT024239	Urotensin-2 receptor	2837	reviewed	G-protein coupled receptor
Q9ULV5	BXGT024442	Heat shock factor protein 4	3299	reviewed	Transcription factor
P08123	BXGT024477	Collagen alpha-2(I) chain	1278	reviewed
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme
Q99536	BXGT024609	Synaptic vesicle membrane protein VAT-1 homolog	10493	reviewed
Q9BYE2	BXGT024631	Transmembrane protease serine 13	84000	reviewed	Enzyme
Q7L8A9	BXGT025010	Tubulinyl-Tyr carboxypeptidase 1	22846	reviewed
Q9GZV5	BXGT025439	WW domain-containing transcription regulator protein 1	25937	reviewed	Enzyme modulator
Q9Y6M1	BXGT025468	Insulin-like growth factor 2 mRNA-binding protein 2	10644	reviewed	Enzyme
Q9UGM3	BXGT025543	Deleted in malignant brain tumors 1 protein	1755	reviewed	Enzyme
Q86SQ9	BXGT025875	Dehydrodolichyl diphosphate synthase complex subunit DHDDS	79947	reviewed	Enzyme
P61916	BXGT025881	NPC intracellular cholesterol transporter 2	10577	reviewed
Q92888	BXGT026130	Rho guanine nucleotide exchange factor 1	9138	reviewed
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme
Q08477	BXGT026164	Docosahexaenoic acid omega-hydroxylase CYP4F3	4051	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}