Showing entry for Protein arginine N-methyltransferase 3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004893
Protein NameProtein arginine N-methyltransferase 3
Uniport IdO60678
GenePRMT3
Gene Id10196
DomainPrmA
Pfam -  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0031397 negative regulation of protein ubiquitination
Biological Process GO:0006479 protein methylation
molecular function GO:0046872 metal ion binding
molecular function GO:0008168 methyltransferase activity
molecular function GO:0016274 protein-arginine N-methyltransferase activity
molecular function GO:0043022 ribosome binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
Reactome
Pathway Id Pathway Name
R-HSA-3214858 RMTs methylate histone arginines
R-HSA-3247509 Chromatin modifying enzymes
R-HSA-392499 Metabolism of proteins
R-HSA-4839726 Chromatin organization
R-HSA-597592 Post-translational protein modification
R-HSA-8876725 Protein methylation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003872 BXGD000235 Arthritis, Psoriatic Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0037369 BXGD002691 Smoking Behavior and Behavior Mechanisms
C0202236 BXGD004086 Triglycerides measurement
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C1260899 BXGD011841 Anemia, Diamond-Blackfan Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1519383 BXGD013237 Smoking Behaviors Behavior and Behavior Mechanisms
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C3548532 BXGD019121 response to alcohol
C4529962 BXGD023178 Fatty Liver Disease
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein