Showing entry for Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005149
Protein NamePhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma
Uniport IdO75747
GenePIK3C2G
Gene Id5288
DomainC2; PI3Ka; PI3K_rbd; PI3_PI4_kinase; PX
Pfam PF00168   PF00454   PF00794   PF00613   PF00787  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00562 Inositol phosphate metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
3. Environmental Information Processing 3.2 Signal transduction hsa04070 Phosphatidylinositol signaling system
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0016477 cell migration
Biological Process GO:0006935 chemotaxis
Biological Process GO:0014065 phosphatidylinositol 3-kinase signaling
Biological Process GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process
Biological Process GO:0006661 phosphatidylinositol biosynthetic process
Biological Process GO:0048015 phosphatidylinositol-mediated signaling
Biological Process GO:0046854 phosphatidylinositol phosphorylation
Biological Process GO:0039694 viral RNA genome replication
molecular function GO:0016303 1-phosphatidylinositol-3-kinase activity
molecular function GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity
molecular function GO:0005524 ATP binding
molecular function GO:0035091 phosphatidylinositol binding
molecular function GO:0052742 phosphatidylinositol kinase activity
molecular function GO:0016307 phosphatidylinositol phosphate kinase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0016020 membrane
cellular component GO:0005942 phosphatidylinositol 3-kinase complex
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1483255 PI Metabolism
R-HSA-1483257 Phospholipid metabolism
R-HSA-1660499 Synthesis of PIPs at the plasma membrane
R-HSA-1660514 Synthesis of PIPs at the Golgi membrane
R-HSA-556833 Metabolism of lipids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0020473 BXGD001396 Hyperlipidemia Nutritional and Metabolic Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0038868 BXGD002781 Progressive supranuclear palsy Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0523465 BXGD009209 Serum albumin measurement
C0596887 BXGD009648 mathematical ability
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein